Dressings are provided herein having a manifold and a biopolymer layer. The configuration and/or compressibility of the manifold and the biopolymer layer can allow for reduced tissue ingrowth and promote wound healing. Methods of making and using the dressings are also provided herein.

The present disclosure relates generally to wound dressing compositions that detect nitric oxide production in a wound upon application. The wound dressing composition comprises a first layer comprising an absorbent layer, a second layer comprising a reaction pad, a third layer comprising a transparent backing film, and optionally a fourth layer comprising a wicking layer. In the wound dressing composition, the second layer comprises a reaction pad of a dried reaction mixture to detect the presence of nitric oxide in a wound. The wound dressing composition can be a visual indicator of the presence of nitric oxide in a wound; a visual indicator of the wounds healing status.

A wound/bandage protector configured as a wrap, a sock/mitten, or a bandage may be made out of stretchable material. The wrap may have one or more fastening straps as well as possibly a first catch fastening surface. The sock/mitten may have a fastening strap and a sheath. The wrap, the sock/mitten, and the bandages may have apertures and aperture covers. In addition, the wound/bandage protectors as well as the bandages may have diamond or triangular gauze configurations with the gauze pad having three or four primary corners, the primary corners of the gauze pad in most instances being oriented towards edges of the body portion or length or width tangents of the body portion, preferably mid-points or mid-sections of the length or width tangents or body portion edges.