Material comprising a flexible porous hydrophilic polymer foam or fibre matrix comprising two matrix faces and therebetween a structural matrix framework defining a network of cells, having a cell network surface and therein a network of pores and a powder charge comprising antimicrobial additive and/or wound dressing additive, wherein said powder charge is comprised at said matrix face or faces and/or within said cell network or within said structural matrix framework and wherein said additive is micronized, wherein said micronized additive has single particle size population greater than or equal to 1 micron and/or has loss on drying (L.O.D) less than 2% and/or said powder charge additionally comprises and flowing agent and/or bulking agent wherein micronized additive is co-located with said flowing agent and/or bulking agent, method for the preparation thereof comprising micronizing said additive and dosing powder charge to said matrix or a reactive phase for the manufacture of said matrix, devices comprising said material and uses thereof.

An interface dressing (1) comprising an elastomeric matrix (5), the elastomeric matrix (5) being provided with a plurality of through-holes (6), each through-hole (6) having a contour (C) around a central axis (A), in which at least some of the plurality of through-holes (6) are arranged so as to form at least one pattern in which each through-hole (6) is adjacent to at least one other through-hole (6), the adjacent through-holes (6) having contours (C), images of which, when moved in translation in a plane perpendicular to the central axes (A) in order to merge images of said central axes (A) by means of said translational movement, do not become superposed.

Hydration-responsive shape-memory keratin composite fibers are provided. These fibers have a keratin network structure formed by keratin -helices bonded by disulfide bonds. Incorporated within the structure are cellulose nanocrystals (CNCs), which provide hydrogen bonds and stabilize the -helix structure, introducing a hydration-responsive switch. Specifically, the CNCs are configured to arrange and connect the keratin -helices, aligning their coil axis along the fiber axis.

A knit hemostatic bandage provided herein can include a continuous rayon fiber and a continuous glass fiber. The knit hemostatic bandage can have a gauge of between 10 and 30 stitches per inch. The knit hemostatic bandage can have a Young's modulus of elasticity of less than 50 MPa.

The present disclosure provides a medical grade nanofibrilar cellulose hydrogel comprising plant-based chemically and enzymatically unmodified nanofibrillar cellulose hydrogel having a concentration of the nanofibrillar cellulose in the range of 1.4-3.4% by weight, the nanofibrillar cellulose having a number-average diameter of fibrils and/or fibril bundles of 100 nm or less, and a storage modulus in the range of 1-35 Pa. The present disclosure also provides a method for treating a subject in need of treatment of body with implantable material, and a method for manufacturing medical grade nanofibrilar cellulose hydrogel.

An apparatus for promoting circulation through a subcutaneous lymph vascular network may comprise a first manifold layer, a second manifold layer coupled to the first manifold layer, and a cover layer coupled to the second manifold layer. The first manifold may have a first stiffness, and the second manifold may have a second stiffness greater than the first stiffness. In some embodiments, the apparatus may additionally have a fluid interface configured to fluidly couple at least one of the first manifold layer and the second manifold layer to a fluid conductor through the cover layer. The fluid conductor may be coupled to or configured to be coupled to a source of negative pressure.

A wound dressing system includes a control/monitor subsystem with a microprocessor configured for optimizing, wound healing based on wound condition parameters and medication concentrations. An intelligent, wound dressing includes: an inner, patient contact layer; and intermediate reservoir layer configured for retaining a quantity of medication; and an outer cover layer. The control/monitor subsystem can utilize artificial intelligence for optimizing, wound healing outcomes, and can interface with the wound dressing via a hardwired connection, a wireless (RF) connection or via the Internet (cloud).

Illustrative embodiments of a dressing for treating a tissue site may include a fluid transport layer, an offloading layer, and a liquid deflector. The offloading layer may be in fluid communication with the fluid transport layer, and the offloading layer may include a force offloading region and a target region. The liquid deflector may be positioned between the fluid transport layer and the offloading layer. The liquid deflector may be configured to deflect a liquid from the tissue site into contact with the target region of the offloading layer. The target region may be configured to expand for offloading forces at the tissue site. Other dressings, systems, and methods are disclosed.

Absorbent composites suitable for a wide variety of uses (e.g., sorbent drapes, sorbent patches around a fenestration area, tray liners for surgical tools, incontinence pads and liners, other liners, etc.) are provided. The composite includes an absorbent nonwoven. The absorbent nonwoven may comprise a hydroentangled spunbond web. The composite also may comprise a liquid-impermeable film. One or more absorbent nonwovens of a composite may additionally comprise a three-dimensional pattern, for example, a three-dimensional pattern that has been imaged using hydroentanglement. Optionally, any one or more layers of the composites may comprise an antimicrobial additive.

In some embodiments, a dressing assembly may include a dressing bolster, an interface seal, and a base layer. The dressing bolster may include a first side, a second side, and a periphery. The interface seal may be coupled at the periphery of the dressing bolster. The base layer may include a base layer flange configured to be coupled to the dressing and to extend beyond the periphery of the dressing bolster. The dressing assembly may be suitable for treating a tissue site with reduced pressure and for creating an apposition force between a first portion of the tissue site and a second portion of the tissue site. Other systems, apparatus, and methods are disclosed.