An aerator device and a filter system including the same are provided. The aerator device includes: a housing having an inner cavity defined therein, the housing including at least one sidewall and an upper surface connected to the at least one sidewall; a first partition formed within the inner cavity and extending from an upper end to a lower end to define a first cavity and a second cavity; and a second partition formed within the inner cavity between the first partition and a first sidewall of the at least one sidewall and extending from an upper end to a lower end to define a first chamber and a second chamber of the second cavity, and the housing includes an inlet opening communicating with the first cavity and an outlet opening communicating with the second chamber, and the second chamber gradually narrows towards the upper surface of the housing.

Header-equipped air diffusion devices includes, in the header, an air storage unit, on its lower end including inlet(s) for water to be treated, and air supply part(s) and air sending part(s) on the air storage unit upper section. The air diffusion device's air sending part and horizontal tube are connected, air sent from the header being diffused by the air diffusion device, and air sending in the air storage unit is above the air supply part's air supply port. The air storage portion's partition portion, with a 50+mm height, partitions the upper portion into an air supply and an air feeding portion side. The partition portion forms a cylindrical portion and an upper plate portion and the air storage portion's trunk portion serves as part of the air supply portion, and an opening end on a lower end side of the partition portion serves as the air supply port.

A method for modifying the flow capabilities of an existing tangential flow filtration (TFF) system is contemplated in which the processing capabilities of the existing static TFF system may be increased without requiring the addition of additional systems running in parallel. This may be achieved via adjusting or replacing certain of the components of the TFF skid to accommodate a tubing set having a larger (or smaller) internal diameter than the existing tubing set or the tubing set for which the TFF system was originally manufactured. In this fashion, it may be seen that an existing skid may have its flow capabilities dramatically increased. It is further contemplated that a retrofit kit for an existing TFF system for use according to the described method may be provided.

A method for modifying the flow capabilities of an existing tangential flow filtration (TFF) system is contemplated in which the processing capabilities of the existing static TFF system may be increased without requiring the addition of additional systems running in parallel. This may be achieved via adjusting or replacing certain of the components of the TFF skid to accommodate a tubing set having a larger (or smaller) internal diameter than the existing tubing set or the tubing set for which the TFF system was originally manufactured. In this fashion, it may be seen that an existing skid may have its flow capabilities dramatically increased. It is further contemplated that a retrofit kit for an existing TFF system for use according to the described method may be provided.

Disclosed herein are robust disposable alternating tangential flow (ATF) housing and diaphragm pump units and associated methods of manufacturing, testing, wetting, and using the same.

The invention concerns a set of tubular elastic coupling bodies arranged opposing at inlet and outlet of a filter cartridge.

The tubular elastic end coupling, comprises a tube end adapted to fit on the filter cartridge inlet/outlet. The elastic end coupling comprises one or more tubular fluid connections for conveying fluid to and from external means for fluid content separation purposes by said membrane filter cartridge.

The invention concerns a set of tubular elastic coupling bodies arranged opposing at inlet and outlet of a filter cartridge.

The tubular elastic end coupling, comprises a tube end adapted to fit on the filter cartridge inlet/outlet. The elastic end coupling comprises one or more tubular fluid connections for conveying fluid to and from external means for fluid content separation purposes by said membrane filter cartridge.

An automated single-use filtration device, in particular for large-volume filtration processes, comprises an unfiltrate inlet, one or more filter elements, a filtrate outlet and sensors for detecting specific process parameters and regulating mechanisms for adjusting specific process parameters. The sensors and regulating mechanisms are connected to an external monitoring and control system, which is adapted for evaluating and processing sensor data and for piloting the regulating mechanisms based on one or more control algorithms.

An automated single-use filtration device, in particular for large-volume filtration processes, comprises an unfiltrate inlet, one or more filter elements, a filtrate outlet and sensors for detecting specific process parameters and regulating mechanisms for adjusting specific process parameters. The sensors and regulating mechanisms are connected to an external monitoring and control system, which is adapted for evaluating and processing sensor data and for piloting the regulating mechanisms based on one or more control algorithms.

A membrane element having a filtration main body, a header (a water collection portion) that collects treated water from an end portion of the filtration main body and a treated water lead-out portion that leads out the treated water is used. The treated water lead-out portion is connected to a tubular peripheral wall of a water collection pipe that collects treated water solid-liquid-separated by the membrane element, and communicates with an inside of the tubular peripheral wall. The tubular peripheral wall has a thick portion that is thicker in a horizontal direction at an upper-side peripheral wall portion located at an upper side (or at a lower-side peripheral wall portion located at a lower side) in the radial direction of the tubular peripheral wall, and a connecting hole that penetrates the thick portion.