The present disclosure relates to a hemodialysis membrane for the treatment of vascular calcification in hemodialysis patients, especially in chronic hemodialysis patients. The present disclosure further relates to methods of treating vascular calcification in hemodialysis patients, wherein the hemodialysis membrane is characterized in that it comprises at least one hydrophobic polymer and at least one hydrophilic polymer and in that it has a MWRO of between 15 and 20 kD and a MWCO of between 170-320 kD or that the hemodialysis membrane comprises at least one hydrophobic polymer and at least one hydrophilic polymer and has a MWRO of between 8.5 kD and 14.0 kD and a MWCO of between 55 kD and 130 kD.

The present disclosure relates to diffusion and/or filtration devices comprising hollow fiber membranes, e.g., ultrafilters for water purification, plasma filters, or capillary dialyzers for blood purification; housings and end caps for the devices; and methods for the production of the devices.

Hollow-fibre membrane having at least one first curl in the form of a first wave which is characterized by a first oscillation plane and a first wavelength and at least one second curl in the form of a second wave which is characterized by a second oscillation plane and a second wavelength, characterized in that the first oscillation plane and the second oscillation plane confine an angle with one another which is different from zero.

The present invention concerns a filtration membrane bundle (30) comprising a plurality of elongated filtration fibers (40) arranged in a spiraled coil (34); and one or more filaments (50) woven around the plurality of elongated filtration fibers (40) binding one or more adjacent elongated filtration fibers (40) at a predetermined and homogeneous spacing (44,48) from one another wherein each elongated filtration fiber (40) is bound to respective adjacent elongated filtration fibers (40) in a co-planar configuration, and wherein the co-planar configuration of filtration fibers (40) are rolled into a coil (34). Furthermore, a filtration membrane assembly comprising the filtration membrane bundle (30) and a housing and method of providing the filtration membrane bundle (30) are disclosed.

The present invention relates to a method for manufacturing a hollow fiber membrane module by using an open hollow fiber membrane cartridge, and a hollow fiber membrane module manufactured by same, the method for manufacturing a hollow fiber membrane module according to an embodiment of the present invention comprising the steps of: preparing a hollow fiber membrane cartridge; opening the hollow fiber membrane cartridge; arranging a hollow fiber membrane on the opened hollow fiber membrane cartridge; and closing the hollow fiber membrane cartridge on which the hollow fiber membrane is arranged.

Disclosed is a hollow fiber membrane module including a case and a hollow fiber membrane built in the case, wherein the hollow fiber membrane contains a polysulfone-based polymer and a hydrophilic polymer, and satisfies the following (A) and (B), and an amount of an eluted substance contained in a liquid obtained by circulating ultrapure water heated at 37° C. through a passage of an inner surface side of the hollow fiber membrane for 4 hours at 200 mL/min is 1.0 mg/m.sup.2 or less: (A) an insoluble component accounts for less than 3% by mass of the total mass of the hollow fiber membrane when the hollow fiber membrane is dissolved in N,N-dimethylacetamide; and (B) a flexible layer exists on a surface of a functional layer in a wet state and the flexible layer has a thickness of 7 nm or more. The present invention provides a hollow fiber membrane module including a hollow fiber membrane containing a polysulfone-based polymer and a hydrophilic polymer built therein, which elutes little eluted substance and exhibits high biocompatibility, while change in performance due to crosslinking of the hydrophilic polymer is suppressed.

The present invention relates to a composite hollow fiber membrane, a manufacturing method therefor, a hollow fiber membrane cartridge including same, and a fuel cell membrane humidifier, the composite hollow fiber membrane comprising a hollow fiber membrane and a contaminant collection layer coated on the inner surface of the hollow fiber membrane. The composite hollow fiber membrane can prevent performance deterioration of a fuel cell by removing, without a separate gas filtering device, contaminants such as nitrogen oxide (NO.sub.x), sulfur oxide (SO.sub.x), and ammonia (NH.sub.3) during a humidifying process.

The present disclosure relates to devices and processes for the production of hollow fiber membrane bundles. The bundles are used for the manufacture of filtration and/or diffusion devices, e.g., capillary dialyzers.

The present disclosure relates to bundles of hollow fiber membranes and a process for their production. The bundles are used for the manufacture of filtration and/or diffusion devices, e.g., capillary dialyzers.

The invention relates to a method of determining a permeation property of hollow-fibre membranes wherein the permeation property of the hollow-fibre membrane is determined on a hollow-fibre membrane bundle which has been introduced into a housing and has terminally open hollow-fibre membranes at a first end of the hollow-fibre membrane bundle and terminally closed hollow-fibre membranes at a second end of the hollow-fibre membrane bundle. The invention more particularly relates to a method of determining the clearance, more particularly the diffusive clearance of hollow-fibre membranes.