Disclosed are an extendable pressurized-type hollow fiber membrane module which facilitates improvement of filtrate quality through a multistep-filtration, enhanced easiness of installation and maintenance, decrease of footprint, and/or enlargement of filtration apparatus (without causing decrease of permeate flux of a unit hollow fiber membrane), and a filtration apparatus manufactured using the same. The filtration apparatus of the present invention comprises first and second pressurized-type hollow fiber membrane modules, wherein an inlet port of the first pressurized-type hollow fiber membrane module for introducing feed water and an outlet port of the second pressurized-type hollow fiber membrane module for discharging filtrate or air are coupled to each other.

Devices and methods for the filtration of particulates from a liquid stream are provided. A filter cartridge includes a housing configured to be placed in-line with a stream of liquid and a plurality of hollow fiber filter members disposed within the housing. The hollow fiber filter members are potted at one end of the housing and configured to capture particulates from the stream of liquid via surface energy. The filter cartridge can provide low pressure loss filtering and is capable of being placed within a small space.

The present disclosure relates to processes for the production of capillary dialyzers. The processes involve contact-free thermoforming of bundles of hollow fiber membranes. The present disclosure also relates to an apparatus for contact-free thermoforming of bundles of hollow fiber membranes.

An external-pressure type hollow fiber membrane module in which fouling is not likely to occur in a hollow fiber membrane at the time of filtering operation, and which exhibits excellent washability of the hollow fiber membrane is provided. The first end side and the second end side of a plurality of hollow fiber membrane bundles 60 are fixed with adhesive, together with an inner wall surface of the tubular housing 10 or an inner wall surface of the cap. The adhesive-fixed part of the first end side includes a plurality of raw water introduction holes 65 which are formed therethrough in a thickness direction. An external-pressure type hollow fiber membrane module in which the plurality of raw water introduction holes 65 include first group raw water introduction holes 66 formed at positions including central parts of the plurality of hollow fiber membrane bundles 60, respectively, and second group raw water introduction holes 67 formed between the plurality of hollow fiber membrane bundles 60 and between the plurality of hollow fiber membrane bundles 60 and the inner wall surface of the tubular housing 10.

Aspects of the present disclosure relate to filtration systems and methods for production of biologically-produced products, which may include pharmaceutical and/or protein products. Certain biomanufacturing systems described herein comprise a bioreactor (e.g., a perfusion bioreactor, a chemostat) and a filter probe comprising a filter bundle comprising a plurality of hollow fibers (e.g., longitudinally aligned hollow fibers). According to some embodiments, a center-to-center distance between any two hollow fibers within the fiber bundle at one or more points along a length of the fiber bundle is relatively large (e.g., greater than or equal to an average outer diameter of the hollow fibers of the fiber bundle, greater than or equal to 1.1 times a minimum diameter of the two hollow fibers). In some embodiments, the hollow fibers within the fiber bundle are arranged in an array (e.g., a hexagonal, linear, annular, or square array).

Described herein are fluid treatment devices for use in tangential flow filtration, comprising a housing unit and a composite material, wherein the composite material comprises: a support member comprising a plurality of pores extending through the support member; and a non-self-supporting macroporous cross-linked gel comprising macropores having an average size of 10 nm to 3000 nm, said macroporous gel being located in the pores of the support member. The invention also relates to a method of separating a substance from a fluid, comprising the step of placing the fluid in contact with an inventive device, thereby adsorbing or absorbing the substance to the composite material contained therein.

A filtration device includes features for robust filtering capability. In particular, the filtration device includes a filter medium having mixed matrix membranes that include hollow fiber membranes embedded with adsorbents such that the filter medium provides both mechanical and adsorption capability.

The invention relates to a hollow fiber membrane filter for purifying liquids with improved separation properties, comprising a cylindrical housing, first inflow or outflow spaces and second inflow or outflow spaces, each of which surrounds a first and a second end region of the cylindrical housing, the cylindrical housing being embodied in at least one end region such that improved flow of a liquid against the hollow fiber membranes in the interior of the cylindrical housing can take place.

A membrane filter for filtering a liquid by submerged operation, the membrane filter comprising membrane elements arranged horizontally adjacent to one another and including headers, each membrane element including membranes arranged in a vertical longitudinal direction and filtering a liquid permeate from the liquid, a header of the headers that is arranged at a uniform header level and includes a permeate collection cavity, wherein the membranes are connected at a permeate side of the permeate collection cavity, a permeate outlet draining the liquid permeate in an outlet direction horizontally from the permeate collection cavity, and a tube connected at a top of the header and laterally enveloping the membranes of the membrane element, wherein the permeate outlet of each of the membrane elements is connected at a horizontally extending common permeate collector that drains the liquid permeate from the membrane filter.

A hollow fiber membrane restraining apparatus comprising: first and second horizontal wall parts having slits therethrough, wherein the inner walls face one another; and two vertical wall parts erected facing both end parts of the first horizontal wall parts in a horizontal axis direction, wherein a mat stacking part is formed and stacked on the first horizontal wall part such that end parts of mats on which hollow fiber membranes are arranged in a row can be aligned, and the second horizontal wall part is locked onto the vertical wall parts by pushing and restraining the mat stacking part; a header apparatus comprising the same; a hollow fiber membrane module; and a method for manufacturing a hollow fiber membrane module are provided.