Provided is a hollow fiber membrane module comprising: a hollow fiber membrane bundle; a housing; a first adhesively-fixed portion and a second adhesively-fixed portion configured to adhesively fix, at both ends of each of the hollow fiber membranes, with a potting material: the hollow fiber membranes to each other, and the hollow fiber membrane bundle to an inner wall of the housing; and a regulating member 40 configured to regulate arrangement of the hollow fiber membranes, wherein: on an end face outer than the housing of at least one of the first adhesively-fixed portion or the second adhesively-fixed portion, when a range of a circle having a center at a center of the end face and a radius equal to of a radius of the end face is defined as a central portion, and a range other than the central portion is defined as a circumferential portion, a ratio of an area ratio of the regulating member 40 and the potting material to an entire area of the central portion to an area ratio of the regulating member 40 and the potting material to an entire area of the circumferential portion is 0.8 or more and 1.2 or less.

A cartridge is provided for dialysis or other blood processing therapy. In the cartridge, fibers may be substantially uniformly distributed near a midplane, but near an end, in the inter fiber space, there may be void flow channels, which may cause fluid flow in the inter fiber space to transition within a short region to uniform flow with minimal stagnation zones. Void flow channels may be be radially oriented, introducing fluid from the outer circumference, or axially oriented, introducing fluid along the axial direction through passageways through the potting material. The fluid flow in the inter fiber space may be perpendicular to the fibers, or radial with respect to a cartridge longitudinal axis. The cartridge may have blood flow in the inter fiber space, and flow of dialysate or ultrafiltrate in the lumens of the fibers, or the opposite situation.

The present invention relates to systems and methods for filtration and/or dilution of fluids, in particular for the dialysis of blood. The systems comprise a filter device (10) having a fluid chamber (18) and comprising a first lid (20) having arranged thereon a first fluid port (22). The filter device (10) further comprises a second lid (30) having arranged thereon at least a second fluid port (32). The filter device (10) further comprises a plurality of hollow fibers (40) arranged within the housing (12), wherein each of the plurality of hollow fibers (40) comprises a semi-permeable membrane and defines a fluid channel extending longitudinally through an interior of the respective hollow fiber (40). Also, the filter device (10) comprises a fourth fluid port (50) and a fifth fluid port (52) both provided at the fluid chamber (18).

An external circulation-type hollow fiber membrane module which has a high processing capacity and which is capable of inhibiting a to-be-treated liquid within a case from flowing through a short path and efficiently bringing the liquid into contact with a hollow fiber membrane in whichever direction of a vertical direction, a horizontal direction, etc., the liquid flows. An external circulation-type hollow fiber membrane module is provided with: a hollow fiber membrane bundle; a case; and a short-path prevention body that blocks flowing of a to-be-treated liquid in a gap between the hollow fiber membrane bundle and the case, wherein a first end of the hollow fiber membrane bundle is fixed in the case, and the short-path prevention body is provided to the downstream side of a first port which is a liquid flow-in port in the case so as to project from the inner surface of the case.

A membrane distillation device, provided with a membrane distillation module including a plurality of hydrophobic porous hollow fiber membranes, and a condenser for condensing water vapor extracted from the module. The average pore diameter of the porous hollow fiber is 0.01-1 m. The filling ratio of the porous hollow fiber of the membrane distillation module is 10-80%, and the pressure condition for the membrane distillation is equal to or greater than 1 kPa and equal to or less than the saturated vapor pressure of water at the temperature of the water being treated.

An apparatus for removing water vapor from a feed gas is provided that comprises a membrane housing, a membrane that divides a first pressure side and a second pressure side of the membrane housing, a feed gas inlet and outlet on the first pressure side, a sweep gas inlet and outlet on the second pressure side, a sweep gas flow regulator, and a pump. In some embodiments the feed gas can be at ambient pressure and a pressure drop across the membrane can be less than about 1 atm.

The present disclosure relates to a filtration device comprising a plurality of hollow fiber membranes, a process for its production, and its use for the dead-end filtration of infusion liquids.

A device for extracorporeal blood circulation includes a potted body having an oxygenator module including at least two of a plurality of circular hollow fiber mat layers, a heat exchanger module including at least two of the plurality of circular hollow fiber mat layers, a blood inlet port adjacent a first end of the potted body and a blood outlet port adjacent a second end of the potted body. The device includes a gas inlet and outlet port and a fluid inlet and outlet port. A first of the plurality of hollow fiber mats includes a plurality of hollow fibers aligned in a direction that is angled relative to a direction of alignment of the plurality of hollow fibers of a second of the plurality of hollow fiber mats and, the plurality of hollow fiber mats are aligned to have the same orientation as one another.

A hollow fiber membrane element, comprising: a core tube comprising a side face having a plurality of pores; and a hollow fiber membrane group consisting of a plurality of hollow fiber membranes disposed around the core tube, the hollow fiber membrane element being a both open-ended type hollow fiber membrane element in which both ends of the core tube and the plurality of hollow fiber membranes are open. The hollow fiber membrane group includes a first hollow fiber membrane layer composed of a plurality of first hollow fiber membranes disposed so as to surround the core tube and a second hollow fiber membrane layer composed of a plurality of second hollow fiber membranes disposed so as to surround the first hollow fiber membrane layer, and a permeability coefficient of the plurality of first hollow fiber membranes is smaller than a permeability coefficient of the plurality of second hollow fiber membranes.

Disclosed is a hollow fiber membrane module. The hollow fiber membrane module includes a housing including a first fluid inlet, a first fluid outlet, a second fluid inlet and a second fluid outlet, and hollow fiber membrane bundles, each hollow fiber membrane bundle including a plurality of hollow fiber membranes, disposed within the housing so that a first fluid flows inside the hollow fiber membranes and a second fluid flows outside the hollow fiber membranes, and each hollow fiber membrane bundle further includes porous tubes having both ends closed and including a plurality of pores formed on the side surfaces thereof. The hollow fiber membrane module removes a region, into which a fluid flowing outside a hollow fiber membrane bundle has difficulty in permeating, thus allowing the fluid to uniformly flow. Therefore, even if hollow flow membranes are highly integrated, performance of the hollow fiber membrane module may be maximized.