This disclosure relates to the use of a hydrophobic hollow fiber filter for the filtration of cell cultures and other biological perfusions, due to its resistance to fouling, as well as the ability to filter solutions with a high solid content. A hydrophobic hollow fiber filter may be used within a filter housing in conjunction with a process vessel and a traditional separation system. When the system is used with alternating tangential flow or tangential flow filtration, the hydrophobic hollow fiber filter results in more effective filtration of the filtrate, leading to greater concentration of the retentate, even in solution containing high levels of solids.

This disclosure relates to the use of a hydrophobic hollow fiber filter for the filtration of cell cultures and other biological perfusions, due to its resistance to fouling, as well as the ability to filter solutions with a high solid content. A hydrophobic hollow fiber filter may be used within a filter housing in conjunction with a process vessel and a traditional separation system. When the system is used with alternating tangential flow or tangential flow filtration, the hydrophobic hollow fiber filter results in more effective filtration of the filtrate, leading to greater concentration of the retentate, even in solution containing high levels of solids.

Provided is a hollow fiber degassing module which includes a hollow fiber membrane bundle obtained by bundling a plurality of hollow fiber membranes in a cylindrical shape and a cylindrical body receiving the hollow fiber membrane bundle and extending in an axial direction and degasses a liquid by supplying the liquid to the outside of the hollow fiber membrane and depressurizing the inside of the hollow fiber membrane, in which a hollow fiber membrane packing ratio which is a ratio of a sum of an apparent cross-sectional area of the hollow fiber membrane with respect to an apparent cross-sectional area of the hollow fiber membrane bundle is in a range of 43% or less.

Provided is a hollow fiber degassing module which includes a hollow fiber membrane bundle obtained by bundling a plurality of hollow fiber membranes in a cylindrical shape and a cylindrical body receiving the hollow fiber membrane bundle and extending in an axial direction and degasses a liquid by supplying the liquid to the outside of the hollow fiber membrane and depressurizing the inside of the hollow fiber membrane, in which a hollow fiber membrane packing ratio which is a ratio of a sum of an apparent cross-sectional area of the hollow fiber membrane with respect to an apparent cross-sectional area of the hollow fiber membrane bundle is in a range of 43% or less.

A contactor module for a contactor panel includes a frame member and a contactor media coupled to the frame member. The contractor module defines a first side and a second side. The contactor media includes at least one first membrane array including a plurality of first hollow fibers extending along a first fiber axis. The at least one first membrane array defines a first axis. Further, the contactor module includes at least one second membrane array including a plurality of second hollow fibers extending along a second fiber axis. The at least one second membrane array defines a second axis. The at least one first membrane array and the at least one second membrane array is disposed such that a first inclination angle is defined between the first axis and the second axis. Moreover, the first inclination angle is greater than zero degree and less than 180 degrees.

The present invention relates to units for separation of gas mixtures using hollow fiber membranes and may be used in chemical, oil, gas and other industries. More specifically, this invention relates to the structure of the membrane gas separation module which may be applied, for instance, in membrane separation units for helium concentrate. The membrane gas separation module comprises the horizontal body with end covers and membrane cartridges made of a bundle of hollow fibers and located in an inversed manner in relation to the center. The body comprises symmetrical end sections of large diameter which are mated by conical transition sections with the central section of minor diameter. In this case length of end sections corresponds with length restricted by the body end and input area of membrane cartridges, and central section inner diameter is configured to provide both free mounting/dismounting of membrane cartridges and tight fit thereof at the sealing point with ring gaskets. Feed gas input nozzles are located on end sections of the body perpendicularly to its longitudinal axis in front of input areas of membrane cartridges, permeate output nozzles are located on end sections of the body near end covers perpendicularly to the body longitudinal axis. The technical result is reduction of weight and dimensional properties of the membrane module and the whole gas separation unit in general, as well as reduction of labor intensity of operations during mounting/dismounting of body end covers of the membrane module.

The present invention relates to units for separation of gas mixtures using hollow fiber membranes and may be used in chemical, oil, gas and other industries. More specifically, this invention relates to the structure of the membrane gas separation module which may be applied, for instance, in membrane separation units for helium concentrate. The membrane gas separation module comprises the horizontal body with end covers and membrane cartridges made of a bundle of hollow fibers and located in an inversed manner in relation to the center. The body comprises symmetrical end sections of large diameter which are mated by conical transition sections with the central section of minor diameter. In this case length of end sections corresponds with length restricted by the body end and input area of membrane cartridges, and central section inner diameter is configured to provide both free mounting/dismounting of membrane cartridges and tight fit thereof at the sealing point with ring gaskets. Feed gas input nozzles are located on end sections of the body perpendicularly to its longitudinal axis in front of input areas of membrane cartridges, permeate output nozzles are located on end sections of the body near end covers perpendicularly to the body longitudinal axis. The technical result is reduction of weight and dimensional properties of the membrane module and the whole gas separation unit in general, as well as reduction of labor intensity of operations during mounting/dismounting of body end covers of the membrane module.

The present disclosure describes a device and method to clear solutes from a patient's blood while maintaining fluid balance. In some implementations, the device and method is used to assist the filtration functions of a patient's liver or kidney. The device includes a plurality of hollow fibers that pass through a sequence of alternating filtration chambers and infusion chambers. The filtration chambers filter the patient's blood while the infusion chambers rehydrate the filtered blood.

The present disclosure describes a device and method to clear solutes from a patient's blood while maintaining fluid balance. In some implementations, the device and method is used to assist the filtration functions of a patient's liver or kidney. The device includes a plurality of hollow fibers that pass through a sequence of alternating filtration chambers and infusion chambers. The filtration chambers filter the patient's blood while the infusion chambers rehydrate the filtered blood.

A cartridge type hollow fiber membrane module includes: a cartridge type hollow fiber membrane element including a hollow fiber membrane bundle, a distribution cylinder, and an adhesive resin portion; a module case including a module case main body portion which has at least one port corresponding to a supply outlet of filtrate or an undiluted solution on a side surface, and a header which has a port corresponding to a supply outlet of filtrate or an undiluted solution, and accommodating the cartridge type hollow fiber membrane element; a first sealing member disposed to come into contact with the distribution cylinder and the header on an external side of a boundary surface between the supporting portion and the adhesive resin portion; and a second sealing member disposed to come into contact with an outer circumference portion of the distribution cylinder and the module case main body portion.