This disclosure provides, among other things, a filtration device comprising an open bottomed multi-well plate, a planar spacer that comprises apertures, and a porous capillary membrane. In the device, the planar spacer is sandwiched between the multi-well plate and the porous capillary membrane and the planar spacer is bonded to both the multi-well plate and the porous capillary membrane via an adhesive. Kits and methods of making the device are also provide.

A filtration element has one or more rigid inserts in a housing. The inserts are covered with membranes. The element is configured to provide open feed channels beside the inserts. The membranes and inserts are potted at an edge, optionally at only part of an edge such as a corner. Permeate flows between the membrane and the insert to the potted edge. The membranes may be potted in a centrifuge.

An apparatus, comprising a film (103) comprising a network of conductive and/or semi-conductive high aspect ratio molecular structures is presented. The apparatus also comprises a frame (102) arranged to support the film (103) at least at least two support positions so that a free-standing region (101) of the film (103) extends between the at least two support positions. The two or more electrical contact areas electrically coupled to the film (103), and these electrical contact areas are arranged to pass electric charge across the free-standing region (101) of the film (103) at a current between 0.01 and 10 amperes.

An additive manufacturing system including a base assembly and a tray assembly. The base assembly includes a build window, substantially transparent to electromagnetic radiation; a projection system configured to project electromagnetic radiation toward an upper surface of the build window; and a tray seat arranged around a perimeter of the build window. The tray assembly is configured to engage with the base assembly in an engaged configuration and includes: a tray structure defining a registration feature configured to engage the tray seat to locate an aperture proximal to the upper surface of the build window in the engaged configuration; and a separation membrane that is configured to laminate across the upper surface of the build window in response to an evacuation of gas from an interstitial region and configured to separate from the build window in response to injection of gas into the interstitial region.

A filter system (100) for biopharmaceutical processes includes: at least one filter unit (10); and at least one distributor plate (200), against which the filter unit rests. A tubeless distributor unit (202) is arranged within the distributor plate and is fluidically connected to the filter unit. The distributor unit guides the fluid to be filtered to the filter unit and/or receives and discharges the filtered fluid from the filter unit. The distributor unit includes at least one active control element (232; 238), with which a fluid flow (14) through the distributor unit) and the filter unit is controlled in an open loop flow or a closed loop flow. The fluid connection between the filter unit and the distributor plate is tubeless. Also provided are a distributor plate (200) for a filter system (100) for biopharmaceutical processes and a method for producing a filter system (100) for biopharmaceutical processes.

Provided is a sheet laminate that enables the purification performance of a wastewater treatment apparatus to be maintained. A sheet laminate 21 is used in a wastewater treatment apparatus for purifying wastewater using action of microorganisms in the wastewater. The sheet laminate 21 comprises a base material 211 and a gas-permeable non-porous layer 212, the base material 211 being a microporous membrane.

A microfilter, a manufacturing method thereof, and a microfiltration unit for holding the microfilter are provided. The microfilter has: a non-epoxy based microfilm; and a plurality of microholes provided on the surface of the non-epoxy based microfilm and penetrating therethrough via UV laser ablation, wherein the surface of the non-epoxy based microfilm is patterned into predetermined sections for locating isolated targets and quick enumeration.

The invention concerns a filtration assembly (1) for microbiological testing and a method of using the filtration assembly for that purpose. The filtration assembly (1) comprises a ring-like membrane support (10) holding a filtration membrane (11), a cylindrical reservoir (20) of which opposite axial ends have openings and one axial opening is removably and fluid-tightly attachable to the membrane support (10) to define a sample volume adjacent to the filtration membrane (11) on one axial side of the membrane support (10); and a drain member (30) removably and fluid tightly attachable to the membrane support (10) to define a drain channel space adjacent to the filtration membrane (11) on an opposite axial side of the membrane support (10).

Disclosed is a method for manufacturing an analysis chip for analysing a biological sample (1), which method comprises providing a matrix (10) formed in a solid support material in which at least one through hole has been formed (11) and at least one pellet (3), cut out of a sheet (6) of solid and porous analysis material; inserting at least one pellet (3) into the at least one through hole (11) of the matrix (10) by translation of the pellet (3) in a direction at right angles to the lower and upper surfaces of the matrix (10); mechanically assembling at a temperature lower than the melting points of the support and analysis materials by means of a pressing force applied at right angles to the upper surface of the matrix.

The present disclosure relates more to processes for making a filter element that includes a filter membrane having a strip of thermoplastic polymer material laminated thereto, for example, as a strip along an edge of the filter membrane. For example, one such process includes providing a sheet of filter membrane having a first surface and an opposed second surface; providing a strip of thermoplastic polymer material having a first surface and an opposed second surface; contacting the first surface of the strip of thermoplastic polymer material with the first surface of the filter membrane; and softening the strip of thermoplastic polymer material at at least its first surface by irradiation with laser radiation; such that the softened polymer material of the first surface of the strip of thermoplastic polymer material bonds to the first surface of the filter membrane upon hardening.