The invention relates to a multistage membrane distillation apparatus (5000), comprising a plurality of multistage membrane distillation modules (500, 600), the modules being configured to be flowed through in parallel by a liquid (F) to be concentrated. Each module comprises a plurality of serial condensation/evaporation stages (50, 60) configured to be flowed through in series by the liquid to be concentrated. Each condensation/evaporation stage comprises a plurality of parallel condensation/evaporation elements (101, 102) configured to be flowed through in parallel by the liquid to be concentrated. Each condensation/evaporation element comprises at least one condensation unit and at least one evaporation unit. The apparatus further comprises at least one of: a centralized heating stage configured to generate steam and to provide the steam to each of the modules in parallel, and a centralized condensation stage configured to receive steam from each of the modules in parallel and to condensate the steam.

Devices and methods are provided that permit efficient and selective separation of liquid biological specimens into at least two constituent components to facilitate subsequent quantitative and qualitative analysis on at least one analyte of interest in at least one of the components. The devices generally include one or more sample deposition regions supported on a base. Each sample deposition region includes a separation membrane for separating the liquid biological specimen into two different fractions. The first fraction is trapped by the separation membrane while the second fraction passes through the separation membrane and into a respective collection membrane. The separation and collection membranes are easily separable from the devices and can be utilized for further processing and analysis.

The invention relates to a cross flow filtration unit, which provides a planar, rigid filter plate for filtration of liquid media, said plate having a planar membrane, which is fluid tight bonded at its edges to the surface of a partly hollow supporting plate comprising exit openings, internal flow channels, and flow areas for a first liquid medium, and the membrane being in fluid contact with said first liquid medium at its internal surface and being in fluid contact with a second liquid medium at its external surface.

The present invention relates to separation of desired target products from biological, plant, and waste-type material, wherein the desired target products include renewable fuels such as ethanol, biobutanol, and biodiesel, wherein the separation is conducted with a cross-flow filtration system having the ability to separate desired products from both non-viscous and viscous medium.

This disclosure generally relates to purification systems using tangential flow filtration (TFF) (TFF systems) that include at least one single-use, disposable flow path wherein the disposable flow path is comprised of a disposable cassette manifold, disposable tubing (including associated components) and a disposable reactor vessel.

Membrane cell stack arrangement comprising a housing, a stack of membranes defining flow compartments and a fluid manifold system, wherein the direction of flow through the flow compartments is different to the direction of flow through entry and exit openings and the width of the entry and exit openings are each larger than 45% of the width of the flow compartment.

The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methodsincluding high throughput methodsfor screening cells that have been subjected to editing and identifying cells that have been properly edited.

The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methodsincluding high throughput methodsfor screening cells that have been subjected to editing and identifying cells that have been properly edited.

The present disclosure provides for devices, systems and methods for fractionation and concentration of particles from a fluid sample. This includes a cartridge containing staged filters having porous surface in series of decreasing pore size for capture of particles from a fluid sample; and a permeate pressure source in fluid communication with the cartridge; wherein the particles are eluted from the porous surfaces and dispensed in a reduced fluid volume.

The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methodsincluding high throughput methodsfor screening cells that have been subjected to editing and identifying cells that have been properly edited.