A spiral wound membrane module, comprising a perforated core having an axially extending internal bore; at least one membrane packet comprising a folded membrane sheet defining a first outer face, a first inner face, a second outer face and a second inner face, the fold of the folded membrane sheet being a leading end of the membrane packet; a feed sheet positioned between the first and second inner faces so as to be sandwiched by the folded membrane sheet; a first permeate screen adjacent the first outer face of the membrane sheet defining a first permeate channel; a second permeate screen adjacent the second outer face of the membrane sheet defining a second permeate channel; and a fluid impermeable support coupled to the leading edge of the membrane packet. Also disclosed is a method of manufacturing the spiral wound membrane module.

A spiral wound membrane module, comprising a perforated core having an axially extending internal bore; at least one membrane packet comprising a folded membrane sheet defining a first outer face, a first inner face, a second outer face and a second inner face, the fold of the folded membrane sheet being a leading end of the membrane packet; a feed sheet positioned between the first and second inner faces so as to be sandwiched by the folded membrane sheet; a first permeate screen adjacent the first outer face of the membrane sheet defining a first permeate channel; a second permeate screen adjacent the second outer face of the membrane sheet defining a second permeate channel; and a fluid impermeable support coupled to the leading edge of the membrane packet. Also disclosed is a method of manufacturing the spiral wound membrane module.

The present invention is directed to an affinity chromatography device that has a normal flow and which separates a targeted protein from aqueous mixtures. The chromatography device includes a housing containing therein a spiral wound membrane assembly that includes at least one inner intermediate material that forms an outer flow channel, at least one polymer membrane that contains therein inorganic particles, and at least one outer intermediate material that forms an inner flow channel sequentially positioned around a central core having a solid outer wall. An aqueous mixture is passed through the outer flow channel, through the polymer membrane where the targeted protein is removed, and then through an inner flow channel. The affinity chromatography device further includes an inlet flow distributor containing an inlet and an outlet flow distributer containing an outlet. Additionally, the chromatography device has a dimensionless resistance parameter that is less than 0.08.

Provided is a feed spacer for reducing differential pressure of a reverse osmosis element, the feed spacer forming the reverse osmosis element, the feed spacer comprising a plurality of strands disposed in a mesh shape having predetermined intersection points, and wherein a vertical cross section of each of the strands has a rhombic shape such that a pressure loss in the feed spacer is minimized by an effective flow of raw water at an interface of a reverse osmosis membrane, and a nozzle for forming the feed spacer.

A cartridge filter includes a feedwater inlet, a first outlet and a second outlet, a tube arranged at the center of the cartridge filter, an interior volume of the tube being in fluid communication with the first outlet, and a spiral wound filter assembly extending radially outward from the central tube and including a prefilter, a reverse osmosis filter, and a postfilter. The prefilter is located radially outward from the reverse osmosis filter and the postfilter.

Spacers for filtration membranes that are formed from perforated films. The spacer include unperforated regions, which can serve as integrated lamination strips, advantageously omitting the need for separate lamination steps required with woven and nonwoven spacer fabrics while also providing a spacer with a uniform thickness.