Embodiments of the present invention provide the integration of arbitrary flow directing patterns, deposited or integrated on or into the porous permeate spacer in a spiral-wound membrane separation element.

Methods of filtering a liquid feed are disclosed. In one version, the method comprises passing a liquid feed through a single pass tangential flow filtration (SPTFF) system and recovering the retentate and permeate from the system in separate containers without recirculation through the SPTFF system. In another version, the method of filtering a liquid feed, comprises passing a liquid feed through a tangential flow filtration (TFF) system, recovering permeate and a portion of the retentate from the system in separate containers without recirculation through the TFF system, and recirculating the remainder of the retentate through the TFF system at least once. The methods can be performed using an SPTFF or a TFF system that comprises manifold segments to serialize the flow path of the feed and retentate without requiring diverter plates.

Methods of filtering a liquid feed are disclosed. In one version, the method comprises passing a liquid feed through a single pass tangential flow filtration (SPTFF) system and recovering the retentate and permeate from the system in separate containers without recirculation through the SPTFF system. In another version, the method of filtering a liquid feed, comprises passing a liquid feed through a tangential flow filtration (TFF) system, recovering permeate and a portion of the retentate from the system in separate containers without recirculation through the TFF system, and recirculating the remainder of the retentate through the TFF system at least once. The methods can be performed using an SPTFF or a TFF system that comprises manifold segments to serialize the flow path of the feed and retentate without requiring diverter plates.

A filter device includes an inlet manifold, an outlet manifold and membrane filter units. Each membrane filter unit has an inlet opening for a fluid flow to be processed, a first outlet opening for a retentate portion of the fluid flow, and a second outlet opening for a remaining portion of the fluid flow. Each inlet opening is fluidly connected to the inlet manifold, and each first outlet opening is fluidly connected to the outlet manifold. The two membrane filter units are staggered and are not axially aligned with respect to each other. One of the membrane filter units is fluidly connected to the inlet manifold and to the outlet manifold via a first set of conduits, and the other membrane filter unit is fluidly connected to the inlet manifold and to the outlet manifold via a second set of conduits.

A spiral wound membrane module including a specialized endcap assembly including a connecting conduit defining a passageway extending radially inward from its outer periphery, and a differential pressure sensor connected to the passageway of the connecting conduit.

A spiral wound membrane module including a specialized endcap assembly including a connecting conduit defining a passageway extending radially inward from its outer periphery, and a differential pressure sensor connected to the passageway of the connecting conduit.

A filter element comprises a membrane layer; and a feed spacer on the membrane layer, wherein the feed spacer comprises a plurality of unit cells arranged in three dimensions, wherein each of the plurality of unit cells comprises a cavity defined by a triply periodic minimal surface, and wherein the cavities of the plurality of unit cells are interconnected to allow a fluid to pass through the cavities of the plurality of unit cells.

A filter element comprises a membrane layer; and a feed spacer on the membrane layer, wherein the feed spacer comprises a plurality of unit cells arranged in three dimensions, wherein each of the plurality of unit cells comprises a cavity defined by a triply periodic minimal surface, and wherein the cavities of the plurality of unit cells are interconnected to allow a fluid to pass through the cavities of the plurality of unit cells.

A spiral wound membrane module including a specialized end cap assembly including a connecting conduit defining a passageway extending radially inward from its outer periphery, and a differential pressure sensor connected to the passageway of the connecting conduit.

A spiral wound membrane module including a specialized end cap assembly including a connecting conduit defining a passageway extending radially inward from its outer periphery, and a differential pressure sensor connected to the passageway of the connecting conduit.