Methods for analyzing an accumulation of particles on a filter membrane involve analyzing comprise the particle accumulation in an optical analysis system using a light microscope, and then analyzing the particle accumulation in an SEM-EDX analysis system using a scanning electron microscope and energy-dispersive X-ray spectroscopy. In order to simplify and accelerate the testing of the filter membrane both in the optical analysis system and in the SEM-EDX system, the filter membrane is subject to a preparation which includes: (i) fixing the particles to the filter membrane, (ii) coating the particle accumulation with an electrically conductive coating which is produced from a conductivity solution that contains an ionic liquid, and (iii) holding the filter membrane flat or pulling the filter membrane taut.

The extent of fouling of a spiral wound membrane module such as used in water treatment plants can be monitored using one or more sensors disposed between wraps of the membrane. The sensors, including electrodes, can communicate signals to a two-part computing device. A first part is located inside the pressure vessel in which the membrane module is disposed. The first part provides input signals and power to the sensors and receives sensor signals. A second part is located on the outside of the pressure vessel and communicates power to the first part via inductive coupling. The second part wirelessly receives the sensor signals from the first part and processes the signals to determine the extent of fouling of the membrane module.

A device for measuring the membrane fouling index which can measure the modified fouling index (MFI) and the silt density index (SDI) at the same time and quantify the degree of membrane fouling caused by various kinds of membrane fouling materials, such as particulate materials, colloids, organic matters, and so on, in a short period of time.

Embodiments of the disclosure provide a method for evaluating dialyzers used in different medical applications (e.g., hemodialysis). Red blood cell volume lost in a dialyzer is monitored by obtaining blood flowrate measurements and hematocrit measurements at input ports and output ports of the dialyzer. The flowrate and hematocrit measurements are used to determine an accumulation of red cell blood volume in the dialyzer. The measurements may be obtained in a lab environment with an in-vitro blood source or may be obtained in a clinical setting with an in-vivo blood source from a patient.

A benchtop device flow setup for determining the effectiveness of magnetic treatment of feed water for reducing mineral scaling includes two similar branches, both equipped with a reverse osmosis membrane and a pump that operate in the transient regime at the same flow rate and transmembrane pressure. The flow setup is further fed with a solution at the same level of supersaturation measured in a stirred reactor, however, only one branch exposes the feed to a magnetic field.

A filtration system can comprise a pressure pump configured to apply a pressure on fluid flowing between a first chamber and a second chamber. The filtration system can also comprise a flow sensor configured to determine at least one parameter associated with fluid flowing across a membrane deposited between the first chamber and a second chamber. The filtration system can comprise a pressure sensor configured to determine pressure readings of the fluid flowing from the first chamber to the second chamber. The filtration system can comprise a filtration management system configured to cause the pressure pump to apply a constant pressure on fluid flowing across the membrane for a first predetermined time based on the pressure reading. The filtration management system can be configured to cause the pressure pump to reverse the fluid flow across the membrane.

Embodiments of the disclosure provide a method for evaluating dialyzers used in different medical applications (e.g., hemodialysis). Red blood cell volume lost in a dialyzer is monitored by obtaining blood flowrate measurements and hematocrit measurements at input ports and output ports of the dialyzer. The flowrate and hematocrit measurements are used to determine an accumulation of red cell blood volume in the dialyzer. The measurements may be obtained in a lab environment with an in-vitro blood source or may be obtained in a clinical setting with an in-vivo blood source from a patient.

A device for measuring the membrane fouling index which can measure the modified fouling index (MFI) and the silt density index (SDI) at the same time and quantify the degree of membrane fouling caused by various kinds of membrane fouling materials, such as particulate materials, colloids, organic matters, and so on, in a short period of time.

Methods of detecting, quantifying and/or characterizing the fouling of a device from a combination of pressure and spectroscopic data are provided. The device can be any device containing components susceptible to fouling. Components can include membranes, pipes, or reactors. Suitable devices include membrane devices, heat exchangers, and chemical or bio-reactors. Membrane devices can include, for example, microfiltration devices, ultrafiltration devices, nanofiltration devices, reverse osmosis, forward osmosis, osmosis, reverse electrodialysis, electro-deionisation or membrane distillation devices. The methods can be applied to any type of membrane, including tubular, spiral, hollow fiber, flat sheet, and capillary membranes. The spectroscopic characterization can include measuring one or more of the absorption, fluorescence, or raman spectroscopic data of one or more foulants. The methods can allow for the early detection and/or characterization of fouling. The characterization can include determining the specific foulant(s) or type of foulant(s) present. The characterization of fouling can allow for the selection of an appropriate de-fouling method and timing.

Methods and devices for real-time detection of fouling chemistry are described herein. In one aspect, a method of detecting and characterizing fouling of a membrane used for separation in a fluid-based system can include illuminating the membrane with one or more light sources, collecting Raman spectroscopy data from the membrane, and based on the Raman data, determining at least one selected from the group consisting of: presence or absence of membrane fouling, severity of membrane fouling, and composition of the membrane fouling, where the Raman spectroscopy is selected from the group consisting of Coherent Anti-Stokes Raman Scattering (CARS), Stimulated Raman Scattering (SRS), and spontaneous Raman Scattering.