A potting material as for use in membrane separation modules maybe provided consisting of a tin alloy having a melting point of from 210 to 230 C., wherein the tin alloy consists, on a metals basis, of: from 95 to 97 wt. %; and from 3 to 5 wt. % of the combination of Silver (Ag) with at least one of Nickel (Ni), Copper (Cu), or Germanium (Ge).

A hollow fiber membrane module according to an aspect of the present disclosure comprises: a hollow fiber membrane bundle that has a plurality of hollow fiber membranes aligned in one direction; a housing that accommodates the hollow fiber membrane bundle; and a potting portion provided around both ends or one end of the hollow fiber membrane bundle, in which space between an outer surface of the hollow fiber membranes and an inner surface of the housing is filled with a potting agent, wherein each of the hollow fiber membranes has a body portion, and an enlarged-diameter portion provided at both ends or one end of the body portion and having an inner diameter enlarged as compared to the body portion, and the enlarged-diameter portion is buried in the potting portion.

In one embodiment is provided a polymer blend of poly(vinyl acetate) (PVAc) and poly(acrylic acid) (PAA), wherein the poly(vinylacetate) is present in an amount ranging between about 20 wt % and about 80 wt %, and poly(acrylic acid) is present in an amount ranging between about 80 wt % and about 20 wt %, based on the total weight of the blend. In another embodiment is provided a fiber produced from this polymer blend, and which has cells therein. In another embodiment is provided a flavorant release material comprising the porous fiber disclosed herein, and one or more flavorants disposed in a longitudinally extending core within the fiber. In another embodiment is provided a polymer fiber membrane containing a hollow, porous fiber formed from the polymer blend disclosed herein. In another embodiment is provided a filter containing the fiber described herein. In another embodiment is provided a process for producing the fibers disclosed herein by addition of the polymers to an extruder or blender, and extruding or melt spinning the mixture into a fiber containing cells therein.

Disclosed herein are an apparatus for heat-treating an inner side surface of a braid for a hollow fiber membrane reinforcement for a water treatment and a braid for a hollow fiber membrane reinforcement manufactured using the heat-treatment apparatus, wherein a fiber tissue forming an inner side surface of a braid becomes dense, and the inner diameter of the braid can be expanded, and the circularity of the inner and outer diameters can be accurate, and a compressive strength can be increased, whereby the physical property of a reinforcement membrane of a hollow fiber can be enhanced, and a filtration reliability and water penetration can be improved, thus obtaining an increased service life of a product and an economical saving effect.

The present invention relates to a hollow microfiber comprising (1) one or more cell-adhesive layers having a cell-adhesive hydrogel, (2) an outer shell layer having a high-strength hydrogel that covers the outer periphery of the cell-adhesive layer that is positioned farthest from the center axis among the one or more cell-adhesive layers, and (3) a cell layer that covers the inner periphery of the cell-adhesive layer that is positioned closest to the center axis among the one or more cell-adhesive layers. The present invention also relates to a method of manufacturing the hollow microfiber and a kit for carrying out the manufacturing method.

A filter module of an extracorporeal blood treatment machine with a filter casing in which a hollow fiber bundle is attached whose hollow fibers comprise a hollow fibre wall made of a semi-permeable membrane, and whereby in their longitudinal extension the hollow fibers comprise a number of changes in their diameter. An amplitude of 0.1 to 1 mm is achieved for the exterior diameter of the respective hollow fiber starting from the hollow fiber's axis, whereby the periodicity provided in the axial direction of the hollow fiber is within a range of 1 to 10 cm and on the inside of the filter casing at least one radial constriction is configured or provided by which the fiber bundle is locally constricted.

In one embodiment is provided a polymer blend of poly(vinyl acetate) (PVAc) and poly(acrylic acid) (PAA), wherein the poly(vinylacetate) is present in an amount ranging between about 20 wt % and about 80 wt %, and poly(acrylic acid) is present in an amount ranging between about 80 wt % and about 20 wt %, based on the total weight of the blend. In another embodiment is provided a fiber produced from this polymer blend, and which has cells therein. In another embodiment is provided a flavorant release material comprising the porous fiber disclosed herein, and one or more flavorants disposed in a longitudinally extending core within the fiber. In another embodiment is provided a polymer fiber membrane containing a hollow, porous fiber formed from the polymer blend disclosed herein. In another embodiment is provided a filter containing the fiber described herein. In another embodiment is provided a process for producing the fibers disclosed herein by addition of the polymers to an extruder or blender, and extruding or melt spinning the mixture into a fiber containing cells therein.

The present disclosure provides extruded or spun, semi-permeable, porous hollow fibres, comprising covalent ester, thioester and/or amide crosslinked polypeptides as well as processes for their production. The hollow fibres may be produced from protein, protein extracts, and/or protein isolates derived from plants, animals, bacteria, algae, archaea, and/or fungi, and in certain embodiments are intended to be suitable for human and/or animal ingestion. In some embodiments, the hollow fibres may be designed to be used in the production of cartridges that are compatible with existing and/or novel bioreactor platforms, for harbouring cell cultures in cultured meat production.

Provided is an isolation and purification method for isolating and purifying extracellular vesicles. In the method for isolating and purifying extracellular vesicles from a solution containing the extracellular vesicles and unnecessary substances. The isolation and purification method is an adsorbent treatment method in which a solution containing the extracellular vesicles and unnecessary substances is brought into contact with an adsorbent to cause the adsorbent to adsorb and retain the unnecessary substances other than the extracellular vesicles. The adsorbent is a porous granular material having a pore, an interior of the pore being positively charged, and the adsorbent can adsorb and retain, in the interior of the pore, negatively charged unnecessary substances other than the extracellular vesicles.

The present invention provides a porous body having high strength, a small pore size, and excellent homogeneity. The porous body of the present invention includes polytetrafluoroethylene and has a microstructure that includes nodes and fibrils. The microstructure further includes, in addition to the nodes and the fibrils, fused points where a fibril that links two nodes and another fibril that links another two nodes are fused with each other.