A cord for supporting a biofilm has a plurality of yarns. At least one of the yarns comprises a plurality of hollow fiber gas transfer membranes. At least one of the yarns extends along the length of the cord generally in the shape of a spiral. Optionally, one or more of the yarns may comprise one or more reinforcing filaments. In some examples, a reinforcing yarn is wrapped around a core. A module may be made by potting a plurality of the cords in at least one header. A reactor may be made and operated by placing the module in a tank fed with water to be treated and supplying a gas to the module. In use, a biofilm covers the cords to form a membrane biofilm assembly.

The present disclosure relates to hollow fiber tangential flow filters, including hollow fiber tangential flow depth filters, for various applications, including bioprocessing and pharmaceutical applications, systems employing such filters, and methods of filtration using the same.

The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.

The problem to be solved by the present invention is to provide a separation film mainly comprising a cellulose-based resin having high permeability. The present invention pertains to a separation film containing a cellulose ester, wherein the separation film is provided with a bicontinuous structure comprising voids and phases containing the cellulose ester, and the width of the voids is 1 to 200 nm inclusive.

A carbon dioxide absorption medium. The absorption medium includes a plurality of hollow fibers and a plurality of binder particles. The hollow fibers have walls comprising a selectively permeable membrane that is configured to permit passage of gaseous carbon dioxide but not liquids. The plurality bind particles are dispersed between the hollow fibers and comprise an absorbent material configured to absorb gaseous carbon dioxide and to bind the carbon dioxide in a solid state.

This disclosure relates to the use of a hydrophobic hollow fiber filter for the filtration of cell cultures and other biological perfusions, due to its resistance to fouling, as well as the ability to filter solutions with a high solid content. A hydrophobic hollow fiber filter may be used within a filter housing in conjunction with a process vessel and a traditional separation system. When the system is used with alternating tangential flow or tangential flow filtration, the hydrophobic hollow fiber filter results in more effective filtration of the filtrate, leading to greater concentration of the retentate, even in solution containing high levels of solids.

A problem to be solved by the present invention is to provide a separation membrane having excellent separation performance, having high membrane strength and high permeation performance, and mainly including a cellulose-based resin. The present invention is concerned with a separation membrane including a cellulose ester, having, in the interior thereof, voids each having a specified structure, and having a tensile elasticity of 1,000 to 6,500 MPa.

The present invention provides a porous body having high strength, a small pore size, and excellent homogeneity. The porous body of the present invention includes polytetrafluoroethylene and has a microstructure that includes nodes and fibrils. The microstructure further includes, in addition to the nodes and the fibrils, fused points where a fibril that links two nodes and another fibril that links another two nodes are fused with each other.

A whole blood hollow fiber membrane filter medium is made of a polymeric material having pores of a pore size that ensures permeability to blood plasma or serum but retains blood cells. The whole blood hollow fiber membrane filter medium is used for filtering a whole blood sample so that blood plasma or serum passes through the whole blood hollow fiber membrane filter medium and blood cells are retained. The obtained blood plasma shows no hemolysis.

Disclosed herein is a single pass cross flow diafiltration system comprising: a filtration module having; two or more filtration segments fluidly connected in series, each having an upstream side and a downstream side; wherein each filtration segment comprises hollow fiber filter membranes, and wherein each filtration segment has a selected length; wherein the hollow fiber filter membranes of each filtration segment have a selected inner diameter; wherein the selected inner diameter of each filtration segment may be the same or different, provided that at least one selected inner diameter differs from another selected inner diameter, and provided that the two or more filtration segments are arranged such that no selected inner diameter in a given filtration segment is larger on the upstream side; one or more pumps, mounted to urge fluid flow; and one or more points of introduction of a diadiluent, each of said points of introduction being fluidly connected to an upstream filtration segment.