The object of the present invention is a new cryopolymerization process that provides crosslinked polymeric materials in the form of a macroporous gel (cryogel) capable of sequestering (neutralize) the anticoagulant heparin, its low molecular weight derivatives (LMWH and ULMWH) and heparinoids, from aqueous solutions, physiological solutions and biological fluids, such as whole blood, serum and plasma. A further object of the invention are also crosslinked polymeric materials in the form of a macroporous gel (cryogel) obtained by the cryopolymerization process of the invention that, thanks to said specific process, result to be comprised of varying proportions of HEMA and HEMA-R monomers. The molar ratio between the components (HEMA/HEMA-R) may vary between 99.9% HEMA:0.1% HEMA-R and 0.1% HEMA:99.9% HEMA-R. Object of the invention is also the use of crosslinked polymeric materials in the form of a macroporous gel (cryogel) obtainable by the cryopolymerization process of the invention for the construction of filters, membranes or devices for the treatment of biological fluids. A further object of the invention are therefore filters, membranes, or devices for the treatment of biological fluids which comprise materials obtained by the cryopolymerization process of the invention.

The object of the present invention is a new cryopolymerization process that provides crosslinked polymeric materials in the form of a macroporous gel (cryogel) capable of sequestering (neutralize) the anticoagulant heparin, its low molecular weight derivatives (LMWH and ULMWH) and heparinoids, from aqueous solutions, physiological solutions and biological fluids, such as whole blood, serum and plasma. A further object of the invention are also crosslinked polymeric materials in the form of a macroporous gel (cryogel) obtained by the cryopolymerization process of the invention that, thanks to said specific process, result to be comprised of varying proportions of HEMA and HEMA-R monomers. The molar ratio between the components (HEMA/HEMA-R) may vary between 99.9% HEMA:0.1% HEMA-R and 0.1% HEMA:99.9% HEMA-R. Object of the invention is also the use of crosslinked polymeric materials in the form of a macroporous gel (cryogel) obtainable by the cryopolymerization process of the invention for the construction of filters, membranes or devices for the treatment of biological fluids. A further object of the invention are therefore filters, membranes, or devices for the treatment of biological fluids which comprise materials obtained by the cryopolymerization process of the invention.

A reverse osmosis membrane and a method for producing the composite reverse osmosis membrane are provided. The reverse osmosis membrane includes a first layer including a polyamide compound, and a second layer including acacia gum. The method includes steps of providing a trimesoyl chloride solution; adding acacia gum to the trimesoyl to form an organic solution; adding the organic solution to an m-phenylenediamine solution to form a mixture; and heating the mixture and rinsing the mixture.

A reverse osmosis membrane and a method for producing the composite reverse osmosis membrane are provided. The reverse osmosis membrane includes a first layer including a polyamide compound, and a second layer including acacia gum. The method includes steps of providing a trimesoyl chloride solution; adding acacia gum to the trimesoyl to form an organic solution; adding the organic solution to an m-phenylenediamine solution to form a mixture; and heating the mixture and rinsing the mixture.

A high-performance thin-film composite polyamide membrane upcycled from a substrate fouled with a biopolymer and a preparation method thereof are provided. The method includes fouling the substrate preferably with the biopolymer to obtain a composite of the substrate and a biopolymer foulant layer; then immersing the composite into a first solution formed by dissolving a polyamine monomer in water, followed by taking the composite out of the first solution and removing excess droplets from a surface of the composite; then immersing the composite treated in the previous step into a second solution formed by dissolving an acyl chloride monomer in n-hexane for interfacial polymerization to form a rejection layer on the surface of the composite; and after completion of the reaction, taking the composite out of the second solution, followed by drying and heat treatment, to obtain the target polyamide membrane.

The present invention is directed to rigid filtration apparatus comprising a filter support and filter membrane. Such filter support is comprised of a central core. Radiating from the central core are a plurality of pleats composed of two angled walls terminating at a contact point. Such longitudinal walls circumscribe a longitudinal channel situated between the walls wherein the longitudinal channel is in communication with the central core. The longitudinal walls are comprised of a plurality of openings along the walls. A filter membrane having biocidal components may be utilized with the filter support to effectively treat contaminated fluid, gas or air. Alternatively, the composition of the rigid central core and the rigid pleats may be composed of different materials to selectively remove chemicals, biological components or pharmaceuticals in a multi-stage treatment process.

The present invention is directed to rigid filtration apparatus comprising a filter support and filter membrane. Such filter support is comprised of a central core. Radiating from the central core are a plurality of pleats composed of two angled walls terminating at a contact point. Such longitudinal walls circumscribe a longitudinal channel situated between the walls wherein the longitudinal channel is in communication with the central core. The longitudinal walls are comprised of a plurality of openings along the walls. A filter membrane having biocidal components may be utilized with the filter support to effectively treat contaminated fluid, gas or air. Alternatively, the composition of the rigid central core and the rigid pleats may be composed of different materials to selectively remove chemicals, biological components or pharmaceuticals in a multi-stage treatment process.

A filtration vessel, having within constituent filter media is formed using plastic injection molding to meet the interior specifications of a high-pressure filtration encasement system while remaining a separate replaceable component. The encasement system supports and encases walls of the filtration vessel enabling the vessel to be designed with sufficient strength and resiliency to form a seal and constrain filter media prior to and after use without necessitating construction to endure independent high-pressure operations. The bottom or base of the vessel includes a plurality of holes through which the filtrate may flow. Interposed between the base of the vessel and the filter media is a semi-permeable barrier imbedded into the injection molded walls and base of the vessel. The barrier prevents residue from contaminating the filtrate.

Embodiments of the present disclosure describe thin-film composite membranes comprising a of the present disclosure further describe methods of preparing membranes, methods of manufacturing membranes, methods of separating chemical species, methods of using the membranes for organic solvent nanofiltration, pervaporation, and the like.

Embodiments of the present disclosure describe thin-film composite membranes comprising a of the present disclosure further describe methods of preparing membranes, methods of manufacturing membranes, methods of separating chemical species, methods of using the membranes for organic solvent nanofiltration, pervaporation, and the like.