An organ implant, such as a heart implant, including a support structure having a plurality of pores and defining passages configured for the growth of blood vessels; and stem cells from at least one soft tissue source of a patient deposited into the pores of the support structure is described. The implant is configured to repair a portion of an organ of the patient.

An interbody fusion cage having upper and lower canals for receiving the heads of bone screws that have been pre-installed in opposing vertebral body endplates. The proximal wall of the cage preferably has a vertical slot that communicates with each canal and is adapted to allow access by a screwdriver and tightening of the screws.

A surgical implant (20) comprises a flexible, areal basic structure (22) having a first face and a second face and being provided with pores (26) extending from the first face to the second face. A barrier layer (24) having a first face and a second face is placed, with its second face, at the first face of the basic structure (2) and attached to the basic structure (22). The barrier layer (24) is deformed into at least part of the pores (26) where it forms, in a respective pore (10), a barrier region (28).

Surgical constructs, assemblies, and methods for rotator cable reinforcement with a flexible coupler and an optional reinforcement material. The rotator cable between the attachment points is reinforced with a suture in different configurations. The anchor points are located at the insertion sites of the rotator cable and a continuous stitch reinforces the rotator cable. The continuous stitch bridges the cable footprint insertion points, to displace forces from the rotator cuff tendon.

A stent for anastomosis of different kinds of organs includes a main body, and at least one fixing unit provided in the main body. At least a portion of the main body is inserted into one of different kinds of organs to be anastomosed with each other, and the rest of the main body is inserted into the other of the different kinds of organs. A distance between the different kinds of organs under the anastomosis is maintained by the fixing units.

Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allows for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.

Methods and the resulting structures, like valve devices (e.g. heart or vessel) are provided made by electrospinning single shapes on mandrels with complex surface shapes. These single shapes are then shaped into valves with a plurality of leaflets. Three levels of complexity of shapes are described: 1) conical shapes, 2) a combination of conical and cylindrical shapes, and 3) a conical and/or cylindrical shape which has further complexity by one or more three-dimensional shapes. Heart valves resulting from these complex electrospun shaped mandrels have better mobility dynamics compared to heart valves electrospun on solely cylindrical mandrels.

Devices, systems, and methods to improve both the reliability of soft tissue repair procedures and the speed at which the procedures are completed are provided. The devices and systems include one or more structured tissue augmentation constructs, which include constructs that are configured to increase a footprint across which suture applied force to tissue when the suture is tied down onto the tissue. The tissue augmentation constructs can be quickly and easily associated with the repair suture and can be useful in many different tissue repair procedures that are disclosed in the application. The present disclosure includes structured tissue augmentation blocks for tendon repair that have a flexible or semi-flexible skeleton integrated into the block. The skeleton can be bioabsorbable and can create both in-plane and out-of-plane curvature in the block.

The present disclosure describes kits for surgical repair of soft tissue defects, including hernias. The kits include any combination of components selected from an implantable sheet, a central tie, a delivery device, an insertion member, and/or a rolling device. Packaging for the kits and/or components and methods of using the kits and/or components are also provided.

The invention relates to a mesh support device (10) for supporting abreast implant (40), wherein the mesh support device (10) comprises a first panel (11) and a second panel (12), of which at least the second panel (12) is a mesh panel (12), which consists of a large number of individual meshes, and wherein the mesh support device (10) further comprises a first arm (31), which has a length Li and is arranged at a first side of the first panel (11), and a second arm (32), which has a length L2 and is arranged at a second side of the first panel (11), the second side being opposite to the first side, wherein each of the first and second arms (31, 32) is configured to be threaded through anyone of said large number of individual meshes and the lengths L.sub.1 and L.sub.2 are chosen such that 30 mm <L.sub.1 <210 mm and 30 mm <L.sub.2 <210 mm. The invention also relates to a method for fixating the breast implant (40) in the support device (10).