The present invention relates to a biocompatible membrane, specifically to a minimally swellable biocompatible membrane and the preparation method thereof. The preparation method of the minimally swellable biocompatible membrane comprises the following steps: synthesis of a copolymer containing a skeleton and a hydrophilic group, the introduction of a biocompatible property, the preparation of a biocompatible membrane solution, and the coating of the biocompatible membrane. The present invention can effectively regulate glucose, and has high biocompatibility (long service life) as well, thereby improving the sensitivity, accuracy, reproducibility, stability, specificity and anti-interference ability in a continuous glucose monitoring (CGM) system, prolonging the life time of the CGM, and greatly reducing the cost of the CGM.

Cationically charged membranes obtainable from curing a composition comprising an aromatic heterocyclic compound, wherein the aromatic heterocyclic compound comprises: a) an aromatic heterocyclic ring: b) at least two polymerisable groups: and c) a cationically charged nitrogen atom. The membranes are mechanically strong, have a high charge density and maintain good permselectivity even after exposure to harsh conditions such as extremes of pH.

A method for forming an isoporous graded film comprising multiblock copolymers and isoporous graded films. The films have a surface layer and a bulk layer. The surface layer can have at least 1?10.sup.14 pores/m.sup.2 and a pore size distribution (d.sub.max/d.sub.min)) of less than 3. The bulk layer has an asymmetric structure. The films can be used in filtration applications.

A method for forming an isoporous graded film comprising multiblock copolymers and isoporous graded films. The films have a surface layer and a bulk layer. The surface layer can have at least 1?10.sup.14 pores/m.sup.2 and a pore size distribution (d.sub.max/d.sub.min)) of less than 3. The bulk layer has an asymmetric structure. The films can be used in filtration applications.

A crosslinked protein-based separation membrane and application thereof. The separation membrane is formed by attaching a crosslinked protein nanomembrane to a porous membrane, the crosslinked protein nanomembrane is formed by crosslinking a two-dimensional nanomembrane which is formed by phase transition of a protein with a crosslinking agent, the separation membrane contains a dense surface layer and a support layer, the dense surface layer is the crosslinked protein nanomembrane, and the support layer is the porous membrane; the protein is any one of lysozyme, bovine serum albumin, insulin, and ?-lactalbumin; the crosslinked protein-based separation membrane has a good biocompatibility, may serve as a dialysis membrane for blood purification, and has a higher retention ratio for large molecular proteins.

Membranes, methods of making the membranes, and methods of using the membranes are described herein. The membranes can comprise a support layer, and a selective polymer layer disposed on the support layer. In some cases, the support layer can comprise a gas permeable polymer and hydrophilic additive dispersed within the gas permeable polymer. In some cases, the selective polymer layer can comprise a selective polymer matrix and carbon nanotubes dispersed within the selective polymer matrix. The membranes can exhibit selective permeability to gases. As such, the membranes can be for the selective removal of carbon dioxide and/or hydrogen sulfide from hydrogen and/or nitrogen.

Disclosed are crosslinked copolymer network, comprising a copolymer, comprising a plurality of zwitterionic repeat units, and a plurality of a first type of hydrophobic repeat units; a plurality of crosslinking units; and a plurality of crosslinks; wherein each crosslinking unit comprises a first terminal thiol moiety and a second terminal thiol moiety; each hydrophobic repeat unit comprises an alkene; and each crosslink is formed from (i) the first terminal thiol moiety of a crosslinking unit and the alkene of a first hydrophobic repeat unit, and (i) the second terminal thiol moiety of the crosslinking unit and the alkene of a second hydrophobic repeat unit; and the method of making such cross-linked copolymer network. Also disclosed are the thin film composite membrane comprising the cross-linked copolymer network; and methods for using such thin film composite membrane.

Disclosed are crosslinked copolymer network, comprising a copolymer, comprising a plurality of zwitterionic repeat units, and a plurality of a first type of hydrophobic repeat units; a plurality of crosslinking units; and a plurality of crosslinks; wherein each crosslinking unit comprises a first terminal thiol moiety and a second terminal thiol moiety; each hydrophobic repeat unit comprises an alkene; and each crosslink is formed from (i) the first terminal thiol moiety of a crosslinking unit and the alkene of a first hydrophobic repeat unit, and (i) the second terminal thiol moiety of the crosslinking unit and the alkene of a second hydrophobic repeat unit; and the method of making such cross-linked copolymer network. Also disclosed are the thin film composite membrane comprising the cross-linked copolymer network; and methods for using such thin film composite membrane.

A multi-layer membrane which has a mixed polyamide selective layer supported on a porous polysulfone layer. The mixed polyamide selective layer includes reacted units of a polyfunctional acyl halide (e.g. trimesoyl chloride) and a diamine mixture containing 4,7,10-trioxa-1,13-tridecanediamine and a cyclic diamine (e.g. piperazine). Methods of fabricating the multi-layer membrane via techniques such as phase inversion and interfacial polymerization are described. The inventive membrane is evaluated on its water flux and salt rejection (e.g. sulfate and chloride salts) capabilities. A water desalination system containing the multi-layer membrane(s) is also provided.

Poly(aryl piperidinium) polymers are provided which have an alkaline-stable cation, piperidinium, introduced into a rigid aromatic polymer backbone free of ether bonds. Hydroxide exchange membranes or hydroxide exchange ionomers formed from these polymers exhibit superior chemical stability, hydroxide conductivity, decreased water uptake, good solubility in selected solvents, and improved mechanical properties in an ambient dry state as compared to conventional hydroxide exchange membranes or ionomers. Hydroxide exchange membrane fuel cells comprising the poly(aryl piperidinium) polymers exhibit enhanced performance and durability at relatively high temperatures.