An annuloplasty ring for repair of mitral valves whose shape can be altered directly or remotely to perform post-implant size and/or shape adjustments. One version of the annuloplasty ring has a size-adjustable remodeling inner core within an outer suture-permeable interface for attaching the ring to an annulus. The inner core has a size-adjustable segment formed by short spaced-apart tubular sections that can move toward and way from one another such as on rails. Alternatively, short sections separated by compressible connectors may be used. One or more tethers may be attached to one side of the size-adjustable segment and pulled from the other side to constrict the segment. Multiple tethers may be connect at different locations around the ring to provide some control over where the ring constricts. An adjustment handle with a flexible shaft may be operated from outside the body to adjust the ring post-implant.

A cardiovascular implant device includes an expandable annular frame and a flow conditioner. The expandable annular frame is formed of a plurality of struts and is configured to conform to an interior shape of a blood vessel or a chamber of a heart when expanded inside the blood vessel or the chamber of the heart. The flow conditioner is connected to the plurality of struts of the expandable annular frame. The flow conditioner is positioned to modify a hemodynamic characteristic of a flow of blood through or out of the expandable annular frame.

A flow diverting apparatus includes a stent frame body, and a stent frame extension.

The stent frame body includes an inlet opening, an outlet opening, and a cavity extending from the inlet opening to the outlet opening. The stent frame body is configured to pass a flow of fluid from the inlet opening to the outlet opening through the cavity. The stent frame body includes a first portion having the inlet opening, and a second portion having the outlet opening. The second portion is tapered from one end of the second portion to a first location of the second portion, thereby forming an indented portion having a plurality of pores. The stent frame extension is configured to be disposed between at least a portion of the indented portion and a vessel wall, thereby preventing a migration of vessel wall cells onto the indented portion.

A stent for a respiratory organ, the stent having an inside surface and an outside surface, includes a base member and a hydrophilic polymer layer. The hydrophilic polymer layer contains a hydrophilic polymer having a hydroxy group and an amide group. The hydrophilic polymer layer is provided on at least a part of the inside surface and/or on at least a part of the outside surface.

A transcatheter heart valve includes a paravalvular seal that is configured for transfemoral delivery. The valve includes a frame and the seal is formed from a plurality of outwardly extending fibers.

A self-expanding biological valve has a fixed support (1), an inflow end support structure (5), an outflow end support structure (3) and a silica gel suture ring (4). The fixing support (1) has a stretching part (2), which is disconnected after being subjected to an expansion force, and then the valve expands at a predetermined position. In an unfolded state, the inflow end support structure (5) and the outflow end support structure (3) extend outwards relative to the fixing support (1) in the radial direction for supporting the valve at the preset position, and continuously applying outward and/or downward force to surrounding tissues, so as to ensure reliable fixation of the valve. The present valve can achieve valve replacement without a complex suture, the operation time is shortened, the risk of complications after operation is reduced.

An annuloplasty ring includes an elastic elongated core having first regions and second regions, wherein the first regions are more stretchable than the second regions and are adapted for positioning at the commissures of a target native heart valve. The first regions and the second regions may enable the annuloplasty ring to both re-establish coaptation of the leaflets of a diseased native heart valve and establish a seal around a prosthetic replacement heart to prevent paravalvular leakage after a Valve In Ring Procedure.

Polymeric heart valve systems having a supportive frame embedded in a polymeric sleeve and a plurality of polymeric leaflets forming a continuum with the polymeric sleeve are described herein. The polymeric leaflets are designed to possess variable thickness throughout and typically are formed having a semi-open profile to reduce stress. Methods of making and using such polymeric heart valve systems are also described.

The present invention discloses a presettable artificial biological aortic valve which comprises a valve seat (1), a valve leaflet stent (2) and three valve leaflets (3), wherein the valve seat (1) is a one-way limiting expandable annular metal seat; the head end of each seat body unit (4) is sequentially provided with a first rivet (7), a limiting protrusion (6) and a first long circular groove (5) from the outside to the inside; the tail end of each seat body unit (4) is sequentially provided with a second long circular groove (8), a second limiting hole (10) and a first limiting hole (9) matched with the limiting protrusion (6), and a second rivet (11) matched with the first long circular groove (5). The presettable artificial biological aortic valve has an original preset state and a normal use state after one-way limiting expansion.

A body implantable penile prosthetic assembly includes a reservoir, a penile implant, and a pump. The reservoir is for containing a saline solution. The penile implant is penile implant operable to shift between a flaccid state in which the penile implant is at least partially depleted of the saline solution and an erect state in which the penile implant receives the saline solution from the one or more reservoirs. The pump is configured to generate pressure that causes the saline solution to flow from the reservoir to the penile implant to cause the penile implant to form the erect state. The penile implant includes a cylinder for receiving the saline solution. The cylinder is formed from a multilayered material having an inner layer comprising polyester and an outer layer comprising silicone.