An exemplary valve repair device for repairing a native valve of a patient includes a coaption element, a pair of paddles, and barb portions. The barb portions extend directly from at least one of the coaption element and the pair of paddles.

Intraocular lenses that include a central portion and one or more peripheral portions. The IOLs includes a sensor housing and a communication member, both of which are secured to the central portion.

The described invention provides an endovascular device comprising a tube comprising at least one side-hole, a first segment comprising a primary opening and a second segment. The side-hole and the first segment form a working lumen. The second segment forms a support lumen where the support lumen is curved to effect: (i) to provide stability to the working lumen of the endovascular device; (ii) to anchor the endovascular device within a blood vessel; (iii) to prevent kickback by resting on an arched anatomical structure; and (iv) to facilitate placement of a second endovascular device distally.

An illustrative stent may comprise an elongated tubular member having a longitudinal axis, the elongated tubular member comprising at least one knitted filament forming a plurality of twisted knit stitches with intermediate rung portions extending circumferentially between radially adjacent twisted knit stitches. Each twisted knit stitch may be interconnected with a longitudinally adjacent twisted knit stitch forming a series of linked stitches. The elongated tubular member may be configured to move between a collapsed configuration and an expanded configuration, wherein in the collapsed configuration the series of linked stitches form longitudinal columns and in the expanded configuration the series of linked stitches extend helically around the elongated tubular member.

The present disclosure provides a method for contracting heart tissue using a transcatheter annuloplasty system. The system includes a plurality of anchoring components, a flexible tightening string and a flexible delivery member. The tightening string is coupled with a first anchoring component and the delivery member. The method includes: implanting the first anchoring component into the heart tissue, the tightening string entering a body along with the first anchoring component, and a proximal end of the delivery member extending outside the body; delivering each of remaining anchoring components, along the delivery member, to the tightening string and implanting it into the heart tissue; and tightening the tightening string. Therefore, after the plurality of anchoring components are implanted at different positions, along a circumferential direction of the mitral annulus, the tightening string is tightened to adjust a spacing of the anchoring components so as to contract the heart tissue.

A stent delivery device having a delivery configuration for delivering a stent to a treatment location and a deployment configuration for deploying the stent at the treatment location may include an outer sheath, an inner shaft slidably disposed within a lumen of the outer sheath, and a distal tip member fixedly attached to a distal end of the inner shaft. A distal portion of the outer sheath may include a plurality of longitudinal strips circumferentially disposed about the lumen of the outer sheath. At least a portion of the distal tip member may be configured to slide over a distal end of the outer sheath in the delivery configuration.

A heart valve anchor apparatus may include a body having a proximal portion and a distal portion. The body may include a first radially expandable portion at the proximal portion of the body, a second radially expandable portion at the distal portion of the body, and a root portion extending from the first radially expandable portion to the second radially expandable portion, the root portion having an outer extent. The first radially expandable portion may be configured to self-expand to an outer extent greater than the outer extent of the root portion when radially unconstrained. The second radially expandable portion may be configured to self-expand to an outer extent greater than the outer extent of the root portion when radially unconstrained. In an unstressed configuration, the body may define a longitudinal centerline that extends away from a plane tangent to the root portion.

An assembly (10) for crimping a frame (56) of an implant (58) comprises a crimping device (20) with a base (22) and a crimping mechanism (24) that defines a crimping aperture (26). A bath (28) having a floor (30), and one or more side-walls (32) extending upward from the floor to a side-wall height defines a receptacle (18) that is shaped to receive a portion of the crimping device. The apparatus has an assembled state in which the portion of the crimping device has been received by the receptacle, the crimping device is held securely by the bath, and the aperture is below the side-wall height. Other embodiments are also described.

Coaptation assist device for repairing cardiac valves and associated systems and methods are disclosed herein. A coaptation assist device configured in accordance with embodiments of the present technology can include, for example, a fixation member configured to press against cardiac tissue proximate to a native valve annulus, and a stationary coaptation structure extending away from the fixation member. The coaptation structure can include an anterior surface configured to coapt with a first native leaflet during systole and a posterior surface configured to displace at least a portion of a second native leaflet. The device also includes at least one sensor configured to detect parameters associated with at least one of cardiac function and device functionality. The sensors can be pressure sensors configured to detect left atrial pressure and/or left ventricular pressure.

The present disclosure relates to an intravascular stent, preparation method and use thereof, and the intravascular stent comprises a positioning segment and a supporting segment, the positioning segment comprising a plurality of first repeating elements, the supporting segment comprising at least two supporting units and at least one connecting unit, the supporting unit comprising a plurality of second repeating elements, the number of the first repeating elements differing from the number of the second repeating elements, a plane formed by front ends of the plurality of first repeating elements being vertical to or intersecting with the axis of the intravascular stent. The intravascular stent of the present disclosure is particularly suitable for iliac vein, with good supporting effect for iliac vein and less damage to venous wall, and can effectively avoid forming in-stent secondary thrombosis after intravascular stent implantation. Moreover, the intravascular stent of the present disclosure can be well positioned in the iliac vein to improve the accuracy of the release, and it is simple for operation. The vascular stent of the present disclosure has the advantages of simple structure, convenient production and low cost, and thereby has important practical significance and good prospect in clinical application.