The present technology relates to intraocular shunting systems and methods. In some embodiments, the present technology includes intraocular shunting systems that include a drainage element having an inflow portion configured for placement within an anterior chamber of the eye outside of an optical field of view of the patient and an outflow portion configured for placement at a different location of the eye. The system can also include a flow control assembly having a rotational control element operably coupled to the drainage element. The flow control assembly can further include an actuation structure coupled to the rotational control element and configured to selectively change an orientation of the rotational control element. An amount of fluid through the inflow portion and/or the outflow portion can vary based on the selected orientation of the rotational control element.

Delivery devices and vascular devices are described for addressing a target site within a body lumen. The delivery device includes one or more ultrasound transducers positioned to transmit and receive ultrasound signals so as to provide an image of an interior of the patient's blood vessel within which the vascular device is disposed in real time, as the procedure is taking place. Using the images provided by the ultrasound transducers, the longitudinal and rotational position of the delivery device (and the vascular device constrained therein) may be adjusted to align the vascular device with the patient's vasculature. In some examples, the vascular device being delivered includes fenestrations, whereas in others the vascular device integral branch grafts.

A covered stent, including a proximal end surface, a distal end surface and a peripheral surface located between the proximal end surface and the distal end surface, the peripheral surface including an inner surface and an outer surface. The outer surface is covered with a first coating membrane, and the inner surface is covered with a second coating membrane. The covered stent further includes a stent main body, which is between the first coating membrane and the second coating membrane. At least one of two ends of the first coating membrane and the second coating membrane fold inward or outward so as to wrap at least one from among the proximal end surface and the distal end surface.

A percutaneous heart valve delivery system including a valve delivery catheter coupled with a first inflatable balloon positioned at a distal end of the valve delivery catheter, wherein the first inflatable balloon is configured to fracture a previously implanted prosthetic heart valve; and a replacement transcatheter heart valve positioned proximal to the first inflatable balloon, wherein the replacement transcatheter heart valve is configured to be implanted subsequently within the previously implanted, fractured prosthetic heart valve, following fracture of the previously implanted heart valve without withdrawal of the percutaneous heart valve delivery system. Also disclosed are methods of implantation of a new heart valve within a previously implanted prosthetic heart valve and methods of valvuloplasty of a native heart valve.

The disclosure relates to an intravascular functional element, in particular an implant, more particularly a Stent, flow diverter, stent graft and intravascular occlusion device, having a radially self-expandable lattice structure which is tubular at least in some regions and which has a wire or a plurality of wires, wherein the wire/at least one of the wires includes a superelastic material, in particular a superelastic material of an alloy with the alloy elements nickel and titanium, wherein a mixed oxide layer is formed on the surface of the wire the wires with a layer thickness of 150 nm to 400 nm, in particular 200 nm to 350 nm, in particular 250 nm to 300 nm.

Apparatus for repairing a heart valve and methods for implanting anchors and repairing a heart valve are provided. The apparatus comprises a body, a member attached to the body at a first end and having a plurality of positioning cords spaced laterally across the member and extending away from a second end of the member opposed to the first end, a tube suspended from the plurality of positioning cords, and an adjustment cord extending through the tube. The method comprises implanting at least one annular anchor in a mitral annulus of the heart valve, implanting a papillary anchor through each papillary muscle of the heart, delivering and positioning an apparatus for repairing a heart valve inside the heart valve using the at least one annular anchor and the papillary anchors, and adjusting the apparatus to adjust the extent of atrial displacement of the heart's mitral leaflets during ventricular contraction.

Some embodiments of the invention advantageously leverage the expansion, dilation or by-pass of the Schlemm's canal using adjustable reversible self-expanding eye stents (SES) or eye tension rings (ETRs) of desired sizes to control and improve aqueous flow throughout the range of the uveolymphatic canal. As such, some embodiments include tension ring(s) or cylinders that sits either inside or outside the Schlemm's canal wall and is at least partially within the canal and/or is partially or fully anchored, attached, adhered, or otherwise held in place with respect to the wall and/or elsewhere in the canal. The partial or complete expansion of the canal can be pre-configured based on pre-operative metrology of the Schlemm's canal to a customized and adjustable fit across the various zones within the uveolymphatic canal and based on the patient specific and evolving needs. Additionally, the SES can utilize entry/exit features for by-pass of fluid, varying control of dilation across its shape that may also allow anchoring, repositioning, and retrieval.

An adjustable valve clip and a valve clamping system are provided. The valve clamping system includes the adjustable valve clip and a pushing device. The adjustable valve clip includes a pushing rod, at least two clip arms, and at least one extension arm. The pushing rod is configured to axially move to drive the clip arm to be unfolded or folded relative to the pushing rod, and drive the extension arm to extend and retract in an axial direction of the clip arm. By setting the extendable and retractable extension arm on a surface of the clip arm of the valve clip, the extension arm can extends beyond the clip arm when the clip arm is opened relative to the pushing rod, which is equivalent to increasing an effective length for gripping the leaflet.

A valve clamping system capable of being independently controlled is provided. The valve clamping system includes a valve clip and a delivery device configured to deliver the valve clip. The valve clip includes a fixing base and proximal clamping pieces capable of being folded or unfolded relative to the fixing base. The delivery device includes a delivery sheath and control parts. The delivery sheath defines at least one pair of first cavities that are symmetrical about an axis of the delivery sheath and axially extend, and each control part movably threads the at least one pair of first cavities. Each control part is connected to one corresponding proximal clamping piece, so as to control the proximal clamping pieces to be folded or unfolded relative to the fixing base.

A method and system provide an ophthalmic lens including a lens body having a chamber therein, a reservoir module coupled with the lens body and an optical fluid. At least part of the lens body is flexible. The reservoir module includes a reservoir and a heat sensitive portion bordering the reservoir. The reservoir has a reservoir volume and is fluidically connected with the chamber. The heat sensitive portion has a shape responsive to a temperature of at least forty five degrees Celsius such that the reservoir volume changes in response to at least part of the heat sensitive portion reaching the temperature. The optical fluid resides in the chamber and the reservoir. A change in the reservoir volume flows a portion of the optical fluid between the reservoir and the chamber such that the flexible portion of the lens body undergoes a shape change corresponding to a base power change.