A deep fryer device, the deep fryer device comprising an enclosure delimited by outer walls and a container suitable for containing a liquid, the liquid being preferably an oil, the deep fryer being connected to a filtration system, the filtration system is configured to receive continuously a flow of the liquid in a closed loop configuration, the filtration system comprising a filter element, wherein the filter element is a membrane filter.

A method and a system for purification of contaminated oil, said method comprising at least two phases: a filter preparation phase which comprises the steps of: ? providing a depth filter by building at least a part of the depth filter from a filter material; and ? impregnating at least a part of said depth filter with a separation aid, and an oil filtering phase comprising the step of filtering contaminated oil through said depth filter which has been prepared during the filter preparation phase.

Depth filters with optimized head space are provided, as well as methods of optimizing the head space in depth filters, and methods of filtration with depth filters having optimized head space, including clarification of flocculated feed streams where pretreatment may include any of lowering cell culture pH, addition of polymers (uncharged or charged), or addition of salts to precipitate out solubilized impurities resulting in high insoluble biomass.

Disclosed herein are methods for removing at least one viral contaminant from a concentrated composition, comprising filtering the concentrated composition through a virus prefilter and a virus filter over one or more filtration cycles, wherein a ratio of the virus prefilter area to the virus filter area in each filtration cycle is at least about 2:1, as well as viral filtration skids for use in such methods.

A method of making depth filtration media, such as for use in a depth filter, are described. The resulting depth filtration media includes a core tube having two or more different layers. The layers can be fibers, such as polymeric or inorganic fibers, wrapped layers of a filter material, or pleated and folded layers of a filter material.

A ballast water production method is provided. The method includes a filtering step that passes raw water supplied into a housing through a filter from a primary side that is upstream of the filter to a secondary side that is downstream of the filter; a volume-increasing step after the filtering step that increases a volume of water present in a space on the secondary side of the housing while the supply of the raw water into the housing is stopped; a pressurizing step after the volume-increasing step that pressurizes an inside of the housing from the secondary side while the supply of the raw water into the housing is stopped; and a rinsing step after the pressurizing step that passes a fluid through the filter from the secondary side to the primary side while the supply of the raw water into the housing is stopped.

According to embodiments of the present disclosure, apparatuses, systems, and methods (e.g., an end-to-end manufacturing platform) for viral vectors are provided that include upstream production and downstream purification to the drug substance stage that is not impacted by the therapeutic vector payload.

A liquid composition for use in purifying an oil contains a polar polymer, a surface active hydrotrope/solubilizer, and a co-tenside. The polar polymer may be a polyalkylene glycol, such as polyethylene glycol. The hydrotrope/solubilizer may be an anionic sulfonic acid, a phosphate ester-based substance or a non-ionic surfactant from the poly-glycoside family. The co-tenside may be at least one amphoteric co-surfactant, such as sodium caprylimino dipropionate.

A modular connector for filtration devices is provided, where each modular connector includes a T-junction, sterile connectors, and a valve. The modular connector may be attached to ports of a filtration device and are configured to be coupled to other identical modular connectors of other filtration devices to facilitate the assembly of a modular manifold assembly that is more compact and has a smaller footprint than convention manifold assemblies. The valves of the modular connectors may be utilized, once the filtration devices are coupled to one another via the modular connectors, to direct a flow path in parallel through the filtration devices or in series through the filtration devices. The modular connectors may further facilitate the connection of any number of filtration devices to create a modular manifold assembly.