An implant or endoprosthesis suitable to be implanted in human or animal tissue includes two (or more than two) parts to be joined in situ. Each one of the parts includes a joining location, the two joining locations facing each other when the device parts are positioned for being joined together, wherein one of the joining locations includes a material which is liquefiable by mechanical vibration and the other one of the joining locations includes a material which is not liquefiable by mechanical vibration and a structure (e.g. undercut cavities or protrusions) suitable for forming a positive fit connection with the liquefiable material. The joining process is effected by pressing the two device parts against each other and by applying ultrasonic vibration to one of the device parts when the two parts are positioned relative to each other such that the two joining locations are in contact with each other.

An eye drop guide for instilling eye drops to an eye includes an eye cup housing and an eye drop dispenser holder. The eye cup housing includes an eye cup at a first end of the eye cup housing configured to be placed over an eye, a hole through the eye cup housing at a second end of the eye cup housing, and a magnet fixed to the eye cup housing at the second end. The eye drop dispenser holder may include a magnet fixed to the eye drop dispenser holder. The magnet in the eye cup housing and the magnet in the eye drop dispenser holder are configured to be attracted to one another so as to removably attach the eye cup housing to the eye drop dispenser holder.

A catheter for prevention of stroke by diverting and filtering the blood flow to carotid and vertebral arteries is provided. The catheter includes at least one balloon with an outer mesh cover that expands upon the balloon inflation and collapses upon balloon deflation. Partial inflation of balloons provides for full mesh expansion in the target vessel with resulting capturing and retrieval of embolic particles. The inflation of the balloon in the aortic arch or head vessels expands the balloon associated filtering mesh leading to both filtering and deflection of embolic particles from the cerebral circulation, while balloon deflation triggers the mesh collapse and promotes its recapturing and retrieval while minimizing the risk of spillage of captured emboli.

The present disclosure provides aortic valve prosthetic devices that are constructed in a non-axisymmetric shape, or are expandable to a non-axisymmetric shape for improved results in the repair of defective aortic valves. The devices can be surgically implanted, or they can be implanted percutaneously through an insertion catheter. The expandable devices can be self-expanding or expanded by an inflatable balloon to a non-axisymmetric cross-section geometry.

A kit and method are presented for making a mobile injury protection device, such as a splint, for protecting an injured body part, such as a limb. The kit includes a formable object and a heating source. The heating source is used to selectively heat the formable object to an elevated temperature, molding the formable object into a required shape for the injury protection device and allowing the molded object to cool to room temperature and become hard again. The formable object may be molded on or around and be in contact with the desired body part. The heating source may include a selectively activated chemical composition, for example by adding water or air to it.

The invention primarily relates to fastening and stabilizing tissues, implants, and/or bondable materials, such as the fastening of a tissue and/or implant to a bondable material, the fastening of an implant to tissue, and/or the fastening of an implant to another implant. This may involve using an energy source to bond and/or mechanically to stabilize a tissue, an implant, a bondable material, and/or other biocompatible material. The invention may also relate to the use of an energy source to remove and/or install an implant and/or bondable material or to facilitate solidification and/or polymerization of bondable material.

The fusion device for fusing a synovial joint of a human or animal patient, in particular a human facet joint, finger joint or toe joint, includes two pin-shaped anchorage portions and arranged therebetween a stabilization portion. The anchorage portions include a thermoplastic material which is liquefiable by mechanical vibration. The stabilization portion preferably has a surface which is equipped for enhancing osseointegration. The anchorage portions have a greater thickness and a greater depth than the stabilization portion. Then the fusion device is pushed between the articular surfaces and mechanical vibration, in particular ultrasonic vibration, is applied to the proximal face of the fusion device. Thereby the liquefiable material is liquefied where in contact with the bone tissue and penetrates into the bone tissue, where after re-solidification it constitutes a positive fit connection between the fusion device and the bone tissue.

Implantable devices including conduits that have markings along the length of the conduit are described herein.

An orthopedic device for implanting between adjacent vertebrae comprising: an arcuate balloon and a hardenable material within said balloon. In some embodiments, the balloon has a footprint that substantially corresponds to a perimeter of a vertebral endplate. An inflatable device is inserted through a cannula into an intervertebral space and oriented so that, upon expansion, a natural angle between vertebrae will be at least partially restored. At least one component selected from the group consisting of a load-bearing component and an osteobiologic component is directed into the inflatable device through a fluid communication means.

The invention relates to an implant for implanting in and/or an eye using fixing means enabling improved fixing, in particular with respect to the natural variability of the anatomical conditions of the eye. According to the invention, the fixing means comprise at least one support element which can be mounted on a tissue structure in the direction traverse to the optical axis of the eye.