A device for improving the function of a heart valve comprises: a support member formed from a shape memory material, and a restraining member providing a restraining action on a course of the support member. The support member may abut one side of the valve conforming to the shape of the valve annulus upon said shape memory material assuming an activated shape while the restraining member restrains the course of the support member. The restraining action is removable for allowing the support member to assume a desired, altered course. The restraining member may be biodegradable to be degraded within a patient or may be detachable from the support member to be withdrawn. The support member according to another embodiment presents a shape change in that an increased cross-section is associated with a shortened length of the support member. The support member according to yet another embodiment has a first and a second activated shape.

A device for adjusting a shape of a coronary sinus in a heart of a patient, the device comprising a flexible tube having: an outer wall extending between a proximal end and a distal end; a first bore extending from the proximal end to the distal end; a proximal flange attached to the proximal end; a distal flange attached to the distal end; wherein, the outer wall includes at least one accordion-like hinge region.

A method of restraining expansion of an atrium of a heart involves accessing a heart of a patient, applying a coating over at least a portion of a surface of an atrium of the heart, and at least partially curing the coating to increase the rigidity thereof. Atrial fibrillation prevention.

Inflatable multi-chambered devices are provided for repairing or replacing spinal discs and distracting neighboring vertebral elements. Also included are cushioning devices that may be used in a joint replacement device cushioning system. Further included are kits and systems that include such devices, methods for making such devices, and methods of treating patients in need of such devices. Examples further include cosmetic augmentation and restoration devices.

Various polymeric materials and delivery systems are described, along with systems and methods for using them for bone and tissue augmentation, such as for the stabilization and/or correction of spinal compression fractures.

A mould adapted to be introduced into a joint of a human patient for resurfacing at least one carrying contacting surface of said joint is provided. The mould is adapted to receive material for resurfacing at least one carrying contacting surface of said joint. The mould is further adapted to be resorbed by the human body or melt after having served its purpose.

An apical implantation mitral valve balloon closure plate blocking body and an implantation method, for human heart repair are disclosed. A balloon closure plate made from an elastic plastic material which may be filled with a gas or a curable liquid is implanted via a small incision on the left side of the chest, enters the left ventricle via the apex, and is placed and fixed at a backflow hole position of a front and rear leaflet closure point of the mitral valve. The present disclosure treats diseases such as functional mitral valve regurgitation, and the success rate for repairing functional mitral valve backflow is more than 90%.

A bone void plug includes a plug body that extends along a longitudinal axis between a proximal face and a distal opening and a recessed opening that extends from the distal opening toward the proximal face. The recessed opening is configured to receive a bone void filler.

Systems, devices and methods for repairing a native heart valve. In one embodiment, a repair device for repairing a native mitral valve having an anterior leaflet and a posterior leaflet between a left atrium and a left ventricle comprises a support having a contracted configuration and an extended configuration, and an appendage, such as a flap or apron extending from the support. In the contracted configuration, the support is sized to be inserted under the posterior leaflet between a wall of the left ventricle and chordae tendineae. In the extended configuration, the support is configured to project anteriorly with respect to a posterior wall of the left ventricle by a distance sufficient to position at least a portion of the posterior leaflet toward the anterior leaflet, and the appendage is configured to extend beyond an edge of the posterior leaflet toward the anterior leaflet.

An orthopedic device for implanting between adjacent vertebrae comprising: an arcuate balloon and a hardenable material within said balloon.

In some embodiments, the balloon has a footprint that substantially corresponds to a perimeter of a vertebral endplate. An inflatable device is inserted through a cannula into an intervertebral space and oriented so that, upon expansion, a natural angle between vertebrae will be at least partially restored. At least one component selected from the group consisting of a load-bearing component and an osteobiologic component is directed into the inflatable device through a fluid communication means.