A prosthetic spacer assembly includes a spacer body, a first anchor, and a second anchor. The first anchor and the second anchor are each connected to the spacer body. The first anchor is configured to capture a first native valve leaflet between the first anchor and the spacer body. The second anchor is configured to capture a second native valve leaflet between the second anchor and the spacer body.

A prosthetic heart valve includes a collapsible and expandable stent having a proximal end, a distal end, an annulus section adjacent the proximal end and an aortic section adjacent the distal end, the stent including a plurality of struts. A cuff may be coupled to the stent so that a flat, bottom edge of the cuff lies adjacent the proximal end of the stent. A pattern of stitches may be circumferentially disposed around the flat bottom edge of the cuff, the pattern of stitches alternating between stitches sewn to the cuff only and stitches sewn to both the cuff and the stent.

An embodiment includes a penile prosthetic comprising: an expandable conduit; a pump; a reservoir; a first conduit that couples the expandable conduit to the pump; a second conduit that couples the reservoir to the pump; and a plate that couples to the expandable conduit, wherein the plate includes a concave surface. Other embodiments are described herein.

Fixation device for fixation of leaflets of a heart valve includes a central assembly and at least one arm moveably coupled to the central assembly. The at least one arm includes a body portion having a first end and a second end and a longitudinal axis defined therebetween, the second end being moveable between a closed position and an open position, the body portion having opposing body lateral sides, each body lateral side extending between the first end and the second end, the body portion having a body portion width defined between the opposing body lateral sides. The at least one arm further includes first and second nondeformable wing extensions, each wing extension extending laterally from a respective lateral side, each wing extension having a lateral outer edge, wherein a maximum arm width is defined between the outer lateral edge of the first wing extension and the outer lateral edge of the second wing extension. The fixation device further includes at least one gripping element moveable relative to the at least one arm to capture a native leaflet therebetween.

A method of implanting a prosthetic heart valve includes advancing a delivery catheter toward a native heart valve, wherein the delivery catheter has a distal capsule containing a prosthetic valve in a compressed state. The prosthetic valve includes a self-expandable interior stent and a self-expandable exterior wire mesh surrounding the interior stent. The exterior wire mesh preferably has a lower radial strength than the interior stent for conforming to a surrounding shape of the native valve. The prosthetic valve is expelled from the distal capsule and allowed to expand within the native valve. Capturing elements extending from a ventricular end of the interior stent trap native leaflets between the capturing elements and an outer surface of the wire mesh.

A device is described. The device includes a suture guide and a tissue retracting surface to enable accurate and safe delivery of sutures through tissue.

A replacement mitral valve prosthesis includes a support structure and a valve body having three flexible leaflets. The support structure preferably includes an internal valve frame and an external sealing frame. The valve frame supports the flexible leaflets. The sealing frame is adapted to conform to the shape of the native mitral valve annulus. The sealing frame may be coupled to an inlet end of the valve frame, an outlet end of the valve frame, or both. A plurality of anchors is coupled to the outlet end of the valve frame. The anchors extend radially outwardly for placement behind native leaflets. The prosthesis preferably includes a skirt disposed along an exterior of the external sealing frame. The prosthesis is collapsible for delivery into the heart via a delivery catheter. The prosthesis is configured to self-expand for deployment in the heart when released from the delivery catheter.

Examples of the disclosure are directed toward a valve device comprising an opening and a leaflet and methods of operating and manufacturing the valve device. In some embodiments, the leaflet is a three-dimensional thin-film leaflet, and the leaflet comprises a dome portion. In a first configuration, the leaflet of the valve device may occlude the opening of the device. In a second configuration, the leaflet may not occlude the opening, and blood may flow across the opening of the device. The valve device may be collapsible for transportation in a catheter.

A side-deliverable prosthetic heart valve includes a valve frame defining an aperture that extends along a central axis and a flow control component mounted within the aperture and configured to permit selective blood flow therethrough. The prosthetic heart valve has a compressed configuration for side-delivery to a heart of a patient via a delivery catheter. The prosthetic heart valve is configured to transition to an expanded configuration when released from the delivery catheter for seating in a native annulus. The valve frame includes distal, proximal, and septal anchoring elements, each of which is insertable through the native annulus prior to seating the prosthetic heart valve therein. The septal anchoring element is configured to extend below the annulus and contact ventricular septal tissue to stabilize the prosthetic heart valve in the annulus when the prosthetic heart valve is seated in the annulus.

A hair implant includes: (a) a hair strand anchor including: an anchor body; at least one hair chamber disposed within the anchor body; and at least one tunnel through the anchor body, where the tunnel is free of a hair; and (b) at least one hair strand having a portion thereof retained in the at least one of the hair chamber; wherein the tunnel is configured to support collagen ligature growth after subcutaneous implantation by receiving and retaining collagen ligatures that anchor the hair implant to a hair implant recipient. Also disclosed is a hair implant including an anchor with first and second anchor bodies and at least one bridge connecting the anchor bodies and bridging at least one void between the anchor bodies, wherein the bridge supports and retains collagen ligature growth. One-piece implants are also disclosed, as are anchors, hair restoration and manufacturing methods.