An expandable intervertebral implant is provided for insertion into an intervertebral space defined by adjacent vertebrae. The expandable intervertebral implant includes a pair of outer sleeve portions and an inner core disposed between the outer sleeve portions. Movement of the inner core relative to the outer sleeve portions causes the outers sleeve portions to deflect away from each other, thereby engaging the expandable intervertebral implant with the vertebrae and adjusting the height of the intervertebral space.

A collapsible and expandable prosthetic heart valve stent is provided and comprising an outer section, a valve support defining a flow channel therethrough, a transition section configured to smoothly transition the outer section to the valve support. The valve support is disposed within an interior defined by the outer section, with the inflow end of the valve support disposed inside the outer section's interior. In some cases, the outflow end of the valve support is at least partially defined by the transition section. The prosthetic leaflets are disposed on the inner surface of the valve support's flow channel and are located at or above the annulus of the heart chamber. A prolapse prevention system is attached to the stent to mitigate native valve leaflet prolapse.

An ophthalmic implant including an intraocular lens (IOL) and at least one drug delivery device. The IOL including an anterior side, a posterior side, a lens, and at least one haptic extending outwardly from the lens and including a first haptic extending from the lens at a first optic-haptic junction. The at least one drug delivery device including a first drug delivery device including a pad and a fixation portion extending from the pad. The pad including at least one therapeutic agent contained therein, an anterior surface, a posterior surface, and a sidewall extending around the pad and between the anterior surface and the posterior surface. The drug delivery device configured for attachment to the IOL via the fixation portion. In an assembled state of the implant, the first drug delivery device is attached to the IOL and the pad overlays the first optic-haptic junction.

An intervertebral spacer implant (80) is provided with a retention mechanism (86) to help alleviate expulsion and movement of the implant when placed in the spine while providing an implant that is easier to insert in the spine. In one embodiment the retention mechanism comprises a keel on at least one of the inferior or superior faces of the spacer implant preferably extending in an anterior-posterior direction. In another embodiment the implant comprises a spacer (84) and a plate (82), the plate comprising a supplemental or alternative retention mechanism. In one embodiment the retention mechanism comprises one or more holes (88) in the anterior end of the plate. In yet another embodiment, the retention mechanism comprises one or more blades that are in a first position when inserted and are preferably rotated to a second position that engages the superior and inferior vertebrae.

Devices, systems and/or methods for repairing soft tissue adjacent a soft tissue repair site. In one embodiment, the repair device includes an anchor member having a base with at least four legs extending from the base. The base extends with a generally flat circular profile defining an upper surface and an underside surface with a central opening extending therethrough. Further, the at least four legs extend from the base with an elongated angled portion, the elongated angled portion being oriented at an angle less than seventy-five degrees relative to the underside surface of the base. With this arrangement, the anchor member may be fixated to soft tissue by rotating the base with a delivery tool so that the elongated angled portion of the at least four legs facilitates the anchor member sinking into the soft tissue and fixating thereto.

Disclosed herein are embodiments related to a method for performing a minimally invasive procedure, the method including delivering an annuloplasty ring in a linear shape using a delivery system. In some embodiments, the delivery of the annuloplasty ring may utilize a trans-septal approach or a trans-apical. In some embodiments, the delivery system may position the annuloplasty ring using a flexible stabilizing mechanism and/or activate one or more anchors to extend outward from the annuloplasty ring.

An implantable medical device for transcatheter delivery, which includes an anchor unit (100) configured to be anchored at an annulus of a cardiac valve of a patient, at least one coupling unit (200) that extends along a first length radially from said anchor unit (100) towards a coaptation line of said valve and including an extension unit (400) extending along a second length. The extension unit (400) is configured to cross between the leaflets of the cardiac valve in order to fill out for an insufficient closing of the valve leaflets of said cardiac valve.

A valve prosthesis (10), comprising a stent (1), a leaflet (2), and a skirt (3); the stent (1) comprises an inflow end, an outflow end, and a plurality of wavy segments axially connected; the wavy segments comprise a plurality of reticular structure units disposed circumferentially; the leaflet (2) and the skirt (3) are fixed on the stent (1) respectively; the upper portion of the skirt (3) is provided with indentations (321); the skirt (3) is fixed with the leaflet (2) by means of the indentations (321); the skirt (3) further comprises first protrusion portions (323) extending toward the direction of the outflow end of the stent; one ends of the first protrusion portions (323) are connected with the indentations (321), and the other ends of the first protrusion portions are fixed to the stent (1); by such a way, the connection strength of the skirt (3) and the stent (1) is enhanced; and besides, when the valve prosthesis (10) is implanted at a lower position, perivalvular leakage preventing height can be increased by means of the first protrusion portions (323), thereby avoiding the leakage of a part of blood from the stent (1) and further improving the perivalvular leakage preventing effect.

A valve clamping device (100) includes a fixing base (20), a pair of clamping arms (40), an actuator assembly (70) and a locking mechanism (80). The actuator assembly (70) includes an actuator shaft (72) movably inserted into the fixing base (20), the actuator shaft (72) moves axially to actuate the clamping arms (40) to be open and closed relative to the fixing base (20), and a positioning portion (720) is provided on the outer peripheral surface of the actuator shaft (72). The locking mechanism (80) includes a locking member (82) and a pushing member (84), a locking hole (820) is provided axially in the locking member (82), the actuator shaft (72) passes through the locking hole (820), and the pushing member (84) abuts against the locking member (82) and is provided obliquely in the fixing base (20), so that an edge (281) of the locking hole (820) is engaged with the positioning portion (720).

An intervertebral implant component of an intervertebral implant includes an outer surface for engaging an adjacent vertebra and an inner surface. A keel extends from the outer surface and is designed to be disposed in a slot provided in the adjacent vertebra. This keel extends in a plane which is non-perpendicular to the outer surface; and preferably there are two of the keels extending from the outer surface which are preferably offset laterally from one another. In another embodiment, an anterior shelf is provided at an anterior end of the outer surface, and this anterior shelf extends vertically away from the inner surface in order to help prevent bone growth from the adjacent vertebra towards the inner surface. Further in accordance with disclosed embodiments, various materials, shapes and forms of construction of the component and/or keel provide various benefits.