An embolic protection device for use in a patient's blood vessel, such as the aorta, has an approximately cylindrical outer structure made of a filter mesh material and an approximately conical inner structure also made of a filter mesh material. On the downstream end of the embolic protection device, the wider end of the conical inner structure is joined to the cylindrical outer structure. The upstream end of the embolic protection device is open for blood to flow between the conical inner structure and the cylindrical outer structure. The space between the conical inner structure and the cylindrical outer structure defines a collection chamber for captured emboli. The narrow upstream end of the conical inner structure has a catheter port with a resilient seal that is sized for passage of a catheter shaft. The filter mesh material may be self-supporting or it may be supported on a resilient-framework or an inflatable framework.

Systems for mitral valve repair are disclosed where one or more mitral valve interventional devices may be advanced intravascularly into the heart of a patient and deployed upon or along the mitral valve to stabilize the valve leaflets. The interventional device may also facilitate the placement or anchoring of a prosthetic mitral valve implant. The interventional device may generally comprise a distal set of arms pivotably and/or rotating coupled to a proximal set of arms which are also pivotably and/or rotating coupled. The distal set of arms may be advanced past the catheter opening to a subannular position (e.g., below the mitral valve) and reconfigured from a low-profile delivery configuration to a deployed securement configuration. The proximal arm members may then be deployed such that the distal and proximal arm members may grip the leaflets between the two sets of arms to stabilize the leaflets.

Expandable prosthetic devices used for treating a variety of conditions, including rotator cuff injuries, broken and/or depressed bone fractures, infection and/or inflammation in the body. In one embodiment, a prosthesis includes an implant having a pressure regulating valve. The implant is capable of being positioned between a first tissue and an opposing second tissue in a void space and of deforming under pressure in response to articulation of a joint. The pressure regulating valve is configured to open based on a predetermined pressure in the implant.

A positioning anchor is provided for a stent-graft for implantation to treat a damaged body lumen. The positioning anchor is generally tubular surrounding a primary fluid conduit. Arms extend laterally from the generally tubular structure of the anchor surrounding lateral fluid conduits. The form of these arms is preferably custom configured to match a particular patient's luminal geometry. The anchor thus fits within the luminal geometry to remain in a desired fixed position for implantation of the anchor and any stent-graft coupled to the anchor. The anchor is most preferably formed with two walls having a void therebetween which can be filled with fixation media to further secure the anchor at the desired implantation site. A lumen shaper balloon and delivery catheter are also disclosed for proper delivery, expansion and inflation of the positioning anchor and stent-graft elements according to this invention.

An intravascular cuff acts as a lining between a native vessel and an intravascular prosthetic device. During deployment, the ends of the cuff curl back upon themselves and are capable of trapping native tissue, such as valve leaflet tissue, between the ends. The cuff creates a seal between the vessel and the prosthetic, thereby preventing leakage around the prosthetic. The cuff also traps any embolic material dislodged from the vessel during expansion of the prosthetic.

In various embodiments, implants including reservoirs, such as intraocular lenses, feature flexible membranes and valves integrated therewith, the valves having apertures that are normally closed.

An injection port assembly for a tissue expander and/or mammary prosthesis comprising a composite silicone matrix having embedded fiber layers. The composite matrix materials may cover or extend from the outside perimeter of the injection port assembly and provide self sealing polymeric materials if punctured by a needle. The tissue expander and injection port assemblies and structures may be formed of MR scannable materials. The injection port structures may have palpation lumps for locating the injection port structure subsequent implantation. The injection port structure may be remotely located from the tissue expander and connected thereto via tubing.

An apparatus for delivery of a device into a hollow organ and a method of delivery are provided. The apparatus includes an elongated tube having proximal and distal openings and being configured for carrying the device on a distal portion thereof. The apparatus further includes a tubular cover for covering at least a portion of the device when mounted on the elongated tube, the tubular cover being radially elastic and axially non-elastic. The tubular cover is retrievable into the elongated tube through the distal opening, such that when the device is mounted on the elongated tube and covered by the tubular cover, retrieval of the tubular cover into the elongated tube uncovers the device for delivery into the hollow organ.

A prosthesis has a tubular body having a proximal end, a distal end, and a lumen extending through the tubular body and open at each of the proximal end and the distal end. The tubular body defines a longitudinal axis and has a first width in a direction perpendicular to the longitudinal axis. The prosthesis also includes a first flange at one of the proximal end and the distal end with the lumen extending through the first flange. The first flange has a second width in the direction perpendicular to the longitudinal axis that is greater than the first width. The tubular body and the first flange form a structurally self-supporting, body compatible, and body absorbable device. The device is formed of a composite structure and is adapted for insertion into an opening through a tympanic membrane.

The present invention is an anatomic system which uses the principle of applying higher elastic tonus than the rest tonus of the agonist muscles to provide the function of the antagonist muscles, and which is designed in a simplest way to provide the said purpose and which can be integrated to the body. The static mechanism of the invention is an elastic mechanism which applies a continuous stable tension in order to keep the joints open. The tension of the mechanism is calibrated by increasing or decreasing the amount of the liquid in a chamber which has flexible and elastic walls up to a certain via a port. In the dynamic mechanism of the invention, the tension applied by the elastic mechanism can be changed according to the motion the patient wants to perform.