A prosthetic heart valve for implant in a human. The valve includes a wireform with undulating inflow cusps and outflow commissure posts to which flexible leaflets attach and coapt in a flow area. Each leaflet may drape over the top of the wireform in the cusp area, but have tabs that each extend underneath the wireform at the commissure posts to be secured along with a tab of an adjacent leaflet. The prosthetic heart valve may also be a dual-wire wireform, with the leaflets sandwiched therebetween. One wireform may be larger than the other, with the leaflets extending over the smaller wireform. The smaller wireform may have commissures that bend radially outward from the larger wireform to provide structure to which the leaflet tabs attach.

Provided is a bioresorbable stent including a stent substrate including a bioresorbable polymer and a contrast medium containing an iodine component, coated on the stent substrate. Since the stent according to the present invention is absorbed in and removed from the human body after a predetermined time, it has excellent biodegradability since it has improved radiopacity by iodine contrast medium coating, it has a high radiography contrast and is very efficient even when a procedure is performed with real time radiography, and since it has low foreshortening and high flexibility, radial force, and re-coil, it may be useful for insertion into a blood vessel having a small diameter, an acute occlusive lesion, an imminent occlusive lesion, and the like.

Interbody fusion devices and related methods of manufacture are described herein. An example interbody fusion device can include a plurality of vertebral endplates, and a body extending between the vertebral endplates. The body and the vertebral endplates can define an internal cavity. Additionally, each of the vertebral endplates can include a lattice structure and a frame surrounding the lattice structure, where the lattice structure being configured to distribute load. Each of the vertebral endplates can also include a plurality of micro-apertures having an average size between about 2 to about 10 micrometers (m), and a plurality of macro-apertures having an average size between about 300 to about 800 micrometers (m).

A system for managing female incontinence includes a body of biocompatible material configured to fit between the labia minora and the vestibule floor, the body having a surface configured to occlude the urethral meatus, an adhesive carried on at least a first portion of the surface and configured to provide a sealing engagement between the body and the urethral meatus, and a substance carried by at least one of the body and the adhesive and configured for controlling the odor of the general vaginal-urethral area of a female.

An intradiscal shield and an exterior shield configured to prevent re-herniation and to provide structural integrity to a spinal defect within or on a spinal disc. An insertion instrument to insert the intradiscal shield within the spinal defect and attach the intradiscal shield or exterior shield to the spinal disc. The insertion instrument having a distal tip for spraying a protein crosslinking reagent within the spinal defect. The exterior shield configured for attaching to the exterior wall of the spinal disc and blocking an exterior opening of the spinal defect.

A hip prosthesis device including a femoral stem, the femoral stem including an elongate stem sleeve having a blind hole extending in a longitudinal direction and a hole opening at an upper frontal end of the stem sleeve; a stem core having an elongate stem shaft inserted in the blind hole and slidable in the longitudinal direction, a neck having a lower neck portion and an upper neck portion, a lower end of a lower neck portion attached to an upper end of the stem shaft, the upper neck portion attachable to a femoral head; a shock absorber mechanism operatively provided between the stem shaft and the stem sleeve to act against a downwardly directed longitudinal sliding motion of the stem shaft relative to the stem sleeve; and a closure cap positioned to close the hole opening with a through hole which the neck extends with its lower neck portion.

Implantable devices such as stents, coils, implantable contraceptives, vascular plugs, vena cava filters, left atrial appendage (LAA) closure devices employing an adhesive component to assist in securing or holding the implant in place within a lumen of a patient's body.

An artificial femoral ball head having a multilayer shell-core composite structure includes a spherical shell layer, a transition layer and an inner core. The inner core is made of a toughened ceramic, the spherical shell layer is made of a ceramic material, and the transition layer is made of a composite material comprising materials of the inner core and the spherical shell layer. The artificial femoral ball head is manufactured through sintering a green body of successively stacked layers of the spherical shell layer, the transition layer and the inner core, and the green body of successively stacked layers is obtained through a powder co-injection molding process. The spherical shell layer of the artificial femoral head has a high rigidness, corrosion-proof and wear-proof performance. The inner core of the artificial femoral head has a high toughness and shockresistant performance.

Medical devices that include a tubular member with a plurality of braided filaments, each filament crossing another of the filaments at a respective crossing point forming sidewall and a plurality of pores in the sidewall that are sized to inhibit flow of blood through the sidewall into an aneurysm to a degree sufficient to lead to thrombosis and healing of the aneurysm when the tubular member is positioned in a blood vessel and adjacent to the aneurysm, the pores have an average pore size that is less than or equal to about 500 microns when the tubular member is in an expanded state, the filaments possessing antithrombogenic surfaces to increase antithrombogenicity of the medical device with pores substantially free of webs formed by antithrombogenic material, such that fewer than 5% of the crossing points have webs formed by antithrombogenic material thereby permitting the pores to be substantially free of webs.

Interbody fusion devices and related methods of manufacture are described herein. An example interbody fusion device can include a plurality of vertebral endplates, and a body extending between the vertebral endplates. The body and the vertebral endplates can define an internal cavity. Additionally, each of the vertebral endplates can include a lattice structure and a frame surrounding the lattice structure, where the lattice structure being configured to distribute load. Each of the vertebral endplates can also include a plurality of micro-apertures having an average size between about 2 to about 10 micrometers (?m), and a plurality of macro-apertures having an average size between about 300 to about 800 micrometers (?m).