The present disclosure relates to hollow fiber tangential flow filters, including hollow fiber tangential flow depth filters, for various applications, including bioprocessing and pharmaceutical applications, systems employing such filters, and methods of filtration using the same.

Algae harvesting and cultivating systems and methods for producing high concentrations of algae product with minimal energy. In an embodiment, a dead-end filtration system and method includes at least one tank and a plurality hollow fiber membranes positioned in the at least one tank. An algae medium is pulled through the hollow fiber membranes such that a retentate and a permeate are produced.

Algae harvesting and cultivating systems and methods for producing high concentrations of algae product with minimal energy. In an embodiment, a dead-end filtration system and method includes at least one tank and a plurality hollow fiber membranes positioned in the at least one tank. An algae medium is pulled through the hollow fiber membranes such that a retentate and a permeate are produced.

This disclosure relates to the use of a hydrophobic hollow fiber filter for the filtration of cell cultures and other biological perfusions, due to its resistance to fouling, as well as the ability to filter solutions with a high solid content. A hydrophobic hollow fiber filter may be used within a filter housing in conjunction with a process vessel and a traditional separation system. When the system is used with alternating tangential flow or tangential flow filtration, the hydrophobic hollow fiber filter results in more effective filtration of the filtrate, leading to greater concentration of the retentate, even in solution containing high levels of solids.

Disclosed are methods of treating wastewater using a membrane bioreactor and achieving a target phosphorus concentration for the membrane permeate stream. These methods include the steps of dosing a wastewater stream with a rare earth clarifying agent and passing the dosed wastewater stream through the membrane to obtain a membrane permeate stream with a permeate concentration that is less than the phosphorus concentration of the influent stream. This permeate concentration also can be equal to or less than a target phosphorus concentration. In the methods as disclosed herein, the rare earth clarifying agent can be chloride salts of one or more rare earth elements and in certain embodiments, the rare earth clarifying agent can be CeCl.sub.3 and LaCl.sub.3.

A method of removing carbon dioxide from a carbonate-containing diaminoalkane solution, the method including passing the carbonate-containing diaminoalkane solution through a membrane module, and a method of preparing diaminoalkane including the same.

A biological reactor system treats concentrated contaminated water with a combination of upflow and downflow bioreactors that are downstream from a reverse osmosis or other concentrator. The system may have a fail safe configuration where flush water may be introduced to the reactors in the event of a power failure or when taking the reactors offline. Many reverse osmosis systems introduce antiscalant treatments upstream so that the reverse osmosis filters do not scale. However, such treatments result in superconcentrated conditions of the antiscalants in the contaminated water processed by the bioreactors. A flushing system may deconcentrate the bioreactors to prevent the antiscalants from precipitating and fouling the bioreactors.

A biological reactor system treats concentrated contaminated water with a combination of upflow and downflow bioreactors that are downstream from a reverse osmosis or other concentrator. The system may have a fail safe configuration where flush water may be introduced to the reactors in the event of a power failure or when taking the reactors offline. Many reverse osmosis systems introduce antiscalant treatments upstream so that the reverse osmosis filters do not scale. However, such treatments result in superconcentrated conditions of the antiscalants in the contaminated water processed by the bioreactors. A flushing system may deconcentrate the bioreactors to prevent the antiscalants from precipitating and fouling the bioreactors.

A desalination system (100) having an intake unit (110) providing seawater to a pre-treatment unit (120) connected to a reverse osmosis (RO) desalination unit (130) and a post treatment unit (150). The desalination system (100) is configured to operate without any external addition of chemicals to simplify logistics and regulation concerns. The units of the system are configured to prevent biofouling, scaling and corrosion by mechanical and biological means including high flow speeds, biological flocculation of colloids, and making the water entering the RO units inhospitable to bacteria and other organisms that cause biofouling, hence preventing their settlement and removing them with the brine. Recovery rate is lowered and energy is recovered to increase the energetic efficiency and minerals that are added to the product water are taken from the brine.

A desalination system (100) having an intake unit (110) providing seawater to a pre-treatment unit (120) connected to a reverse osmosis (RO) desalination unit (130) and a post treatment unit (150). The desalination system (100) is configured to operate without any external addition of chemicals to simplify logistics and regulation concerns. The units of the system are configured to prevent biofouling, scaling and corrosion by mechanical and biological means including high flow speeds, biological flocculation of colloids, and making the water entering the RO units inhospitable to bacteria and other organisms that cause biofouling, hence preventing their settlement and removing them with the brine. Recovery rate is lowered and energy is recovered to increase the energetic efficiency and minerals that are added to the product water are taken from the brine.