A D-allulose syrup including, besides D-allulose, a D-allulose dimer mass content, expressed in terms of dry mass, greater than 1.5%. Also, a method for producing the syrup and the use thereof for producing food or pharmaceutical products.

The present disclosure relates to methods and systems for the continuous production of recombinant proteins. In particular embodiments, the disclosure relates to methods and systems using capture chromatography, post-capture chromatography, virus filtration, and ultrafiltration/diafiltration for the continuous production of recombinant proteins.

The present invention discloses a process for preparing high-purity raffinose from defatted wheat germ comprising the steps of percolate extraction of raffinose from defatted wheat germ, decoloration by extraction from the abstraction liquid, electrodialysis desalination, impurity removal by simulated moving bed, concentration and crystallization, with the absolute purity of raffinose as high as 98% and the recovery up to 75%. The process is not only reliable and easy to operate, but also easy to realize industrial production and control the parameters.

In various embodiments, the present invention provides a process for separating target proteins from non-target proteins in a sample comprising increasing the concentration of the target proteins and non-target proteins in the sample and subsequently delivering the concentrated sample to a chromatography device. In other embodiments, the invention relates to a process for increasing the capacity of a chromatography device for a target protein by delivering a concentrated sample comprising the target protein to a chromatography device.

It is an object of the invention to provide a process for producing an organic acid, comprising: providing an incoming stream containing an organic acid and impurities; subjecting said incoming stream to a step of chromatographic separation, using a solution of mineral acid as an eluent, so as to collect an extract and a raffinate, the organic acid being recovered in the extract; and subjecting the raffinate to an electrodialysis step, so as to collect a diluate and a concentrate, the mineral acid being concentrated in the concentrate. The invention also provides an installation for implementing this process.

The invention relates to methods for preparing a concentrated cannabinoid product optionally also containing an array of terpenes, flavonoids, and other phytoconstituents from a cannabinoid-containing extract feed. The cannabinoid-containing extract feed is contacted with an adsorbent to produce a pre-treated extract which is then subjected to one or more filtration steps, and recovering the concentrated cannabinoid product utilizing an extractant or an evaporator.

Methods of regenerating a strong base anion resin are described. The method comprises collecting a salt-containing product from a chromatographic system configured to process a biomass derived material. The salt-containing product is processed through a nanofiltration membrane to collect a salt-containing permeate, which is used to regenerate a spent strong base anion resin. The biomass may be a plant-based material, such as sugar beets or sugar cane. A system for regenerating a strong base anion resin is also described.

A new method for producing D-allulose crystals that allows for a continuous production process and ensures a high yield. Also, new D-allulose crystals. Further, the use of a nanofiltration unit in a method for producing D-allulose crystals to improve the yield and/or quality of the resulting crystals.

Methods and procedures for operating biologics or biopharmaceutical purification protocols where disparate process steps requiring significantly different process parameters (e.g., pressure and flow rate) as continuous processes without the use of surge tanks, holding tanks or similar.

It is an object of the invention to provide a process for producing an organic acid, comprising: providing an incoming stream containing an organic acid and impurities; subjecting said incoming stream to a step of chromatographic separation, using a solution of mineral acid as an eluent, so as to collect an extract and a raffinate, the organic acid being recovered in the extract; and subjecting the raffinate to an electrodialysis step, so as to collect a diluate and a concentrate, the mineral acid being concentrated in the concentrate. The invention also provides an installation for implementing this process.