A preparation method of sodium hyaluronate with a full molecular weight distribution (MWD) is provided, including: step 1): spraying hydrogen peroxide on a sodium hyaluronate solid raw material, and conducting an ultraviolet (UV) irradiation treatment; step 2): dissolving a sodium hyaluronate degradation material in water, and adjusting a pH to higher than 7.0; step 3): subjecting a sodium hyaluronate alkaline solution to an ultrasonic treatment; step 4): preparing the sodium hyaluronate solid raw material into a sodium hyaluronate solution with a concentration of 0.1% to 1% (w/v), and thoroughly mixing the sodium hyaluronate solution in an addition proportion of 20% to 60% (v/v) with the sodium hyaluronate alkaline solution obtained after the ultrasonic treatment; and step 5): subjecting a resulting mixed solution to an adsorption treatment with diatomaceous earth and activated carbon, filtering for concentration, and drying a resulting concentrate to obtain the sodium hyaluronate with a full MWD.

Disclosed is a continuous process for the purification of steviol glycosides extracted from the dried stevia leaves using continuous simulated moving bed processes and nanofiltration without the addition of organic solvents to obtain a purified steviol product comprising sweet steviol glycosides. The sweet steviol glycosides can be used as substitutes for caloric sweeteners in beverages and in other food items.

A process for preparing a metal hydroxide comprising (i) at least one metal chosen from nickel and cobalt and optionally (ii) at least one metal chosen from manganese, lithium and aluminum. The process comprises: reacting a metal sulfate comprising (i) at least one metal chosen from nickel and cobalt and optionally (iii) at least one metal chosen from manganese and aluminum with sodium hydroxide and optionally a chelating agent in order to obtain a solid comprising the metal hydroxide and a liquid comprising sodium sulfate; separating the liquid and the solid from one another to obtain the metal hydroxide; submitting the liquid comprising sodium sulfate to an electromembrane process for converting the sodium sulfate into sodium hydroxide; and reusing the sodium hydroxide obtained by the electromembrane process for reacting with the metal sulfate.

The invention relates to a method for recovery and purification of a neutral or sialylated human milk oligosaccharide (HMO) from a fermentation broth, comprising the steps of separating the fermentation broth to form a separated HMO-containing stream and a biomass waste stream, purifying the HMO-containing stream by ultrafiltration using an ultrafiltration membrane having a MWCO of 500 Da to 5 kDa, purifying the HMO-containing stream by nanofiltration, concentrating the purified HMO-containing stream, and drying the purified HMO-containing stream to obtain a solidified neutral or sialylated HMO. Moreover, the invention also concerns a neutral or sialylated human milk oligosaccharide obtained by the inventive method, as well as its use in food, feed, and medical application.

A process for preparing metal oxide comprising (i) at least one metal chosen from nickel and cobalt and optionally (ii) at least one metal chosen from manganese, lithium and aluminum. The process comprising: reacting a metal sulfate comprising (i) at least one metal chosen from nickel and cobalt and optionally (ii) at least one metal chosen from manganese, lithium and aluminum with lithium hydroxide and optionally a chelating agent to obtain a solid comprising a metal hydroxide comprising (i) at least one metal chosen from nickel and cobalt and optionally (ii) at least one metal chosen from manganese, lithium and aluminum, and a liquid comprising lithium sulfate, the metal sulfate comprising (i) at least one metal chosen from nickel and cobalt and optionally (ii) at least one metal chosen from manganese, lithium and aluminum; separating the liquid and the solid from one another to obtain the metal hydroxide; submitting the liquid comprising lithium sulfate to an electromembrane process for converting the lithium sulfate into lithium hydroxide; and reusing at least a first portion of said lithium hydroxide obtained by the electromembrane process for reacting with the metal sulfate; reacting at least a second portion of said lithium hydroxide obtained by the electromembrane process with the obtained metal hydroxide to obtain a mixture of metal hydroxides; and roasting said mixture of metal hydroxides to obtain the metal oxide.

Disclosed by the invention is a method for preparing lithium carbonate from lithium ore, comprising the steps of: preparing lithium sulfate leachate from lithium ore concentrate, removing Fe.sup.2+ and Al.sup.3+ from the lithium sulfate leachate by adding alkali, removing Ca.sup.2+ and Mg.sup.2+ from the lithium sulfate leachate by an ion exchange method, adding a saturated solution of soda ash into the obtained concentrated solution of lithium sulfate leachate, precipitating lithium carbonate, filtering and separating the lithium carbonate precipitate, washing with hot water and drying to obtain a finished lithium carbonate product. The invention saves the production cost, and obviously improves the purity of lithium carbonate as a final product. In addition, disclosed by the invention is also a system for realizing the method for preparing lithium carbonate from lithium ore.

Disclosed is a continuous process for the purification of steviol glycosides extracted from the dried stevia leaves using continuous simulated moving bed processes and nanofiltration without the addition of organic solvents to obtain a purified steviol product comprising sweet steviol glycosides. The sweet steviol glycosides can be used as substitutes for caloric sweeteners in beverages and in other food items.

The present invention provides a method for extracting ?-polylysine (?-PL) and its hydrochloride salt from fermentation broth, which belongs to the field of bio-separation engineering. ?-PL and its hydrochloride salt are produced from fermentation broth through sequential solid-liquid separation, ultrafiltration, two-stage ion exchange, nanofiltration, evaporation concentration and drying techniques. Technologies of membrane filtration and two-stage ion exchange are applied to the preparation of ?-PL and its hydrochloride salt in the present invention, and the invention are characterized by reduced cost, improved automation, and increased product yield and purity, and the method of the present invention would be more suitable for industrial production.

A system and process for removing divalent ions from a MEG feed stream is presented. Embodiments of the system include a chemical treatment tank where chemicals are mixed with the feed stream to form insoluble carbonate and hydroxide salts. The system also includes a solid-liquid separation unit that receives the feed stream from the chemical treatment tank and separates it into a liquids portion containing MEG and a insoluble salts portion. The system may also include washing the insoluble salts portion to remove additional MEG, which is then recycled to a MEG regeneration or reclamation process. The system may also include a dryer that receives waste slurry from the solid-liquid separation unit and dries it to form a solid waste, thereby facilitating its handling, storage, and disposal.

A process for preparing a sunflower seed protein isolate and a protein isolate which is obtainable by such process. The process comprises the following steps: mixing a defatted seed meal with an aqueous NaCl solution at a basic pH; separating said solubilised protein solution from solids; diafiltering said solubilised protein solution through an ultrafiltration membrane system using an aqueous NaCl diafiltration NaCl solution and at least 2 diavolumes of said aqueous NaCl diafiltration solution, diafiltering said NaCl-diafiltered protein; concentrating said purified protein solution; and drying said purified protein concentrate to obtain a protein isolate.