Described are filter cartridges, filter apparatuses, and related methods that involve a filter cartridge that includes a cartridge support that includes centering surfaces, a helical strand, or both.

A single-stage water treatment system may include a fine filtration module configured for receiving process material with a high suspended and/or dissolved solids content and for producing a concentrate and a permeate. The fine filtration module may include an elongate housing member, a plurality of tubular membranes arranged within the elongate housing member and comprising elongate tubular members having membranous sidewalls with a selected permeability, a pair of end caps configured for controlling the flow of the process material within the plurality of tubular membranes, and an adjustment mechanism configured to adjust the elongation of the plurality of tubular membranes thereby adjusting the permeability thereof.

A support apparatus for a filter membrane comprises a base support and a disc-shaped porous support member. The member is removably received in a seat portion of the base support in fluid communication with a drain. A bottom side of the disc-shaped porous support member is supported in a support plane. The bottom side of the member is unsupported in an area and the unsupported area is adjacent to a space in the seat portion of the base support that is located and dimensioned such that application of a force, onto the top side of the member at a location substantially within the boundaries of the unsupported area at the bottom side will cause the member to pivot/tilt into the space and lift above the support plane at a diagonally opposite side from the location where the force is applied so that it can be easily grasped and removed.

A filtration apparatus according to an embodiment of the present invention includes at least one filtration module including a plurality of hollow-fiber membranes arranged by being pulled in one direction and a pair of holding members that fix both ends of the plurality of hollow-fiber membranes, and at least one cleaning module that supplies air bubbles from below the filtration module. In the filtration apparatus, the filtration module has a structure in which the plurality of hollow-fiber membranes are arranged to form a curtain-like shape on the holding members each having a shape of a bar, and the holding members each have a plurality of regions in which the plurality of hollow-fiber membranes are densely arranged and which are disposed at intervals in a longitudinal direction.

A sealing case for a filtration cassette that reliably prevents leaks after assembly and installation into a filtration system. The sealing case fits on the filtration cassette and provides a fluid-tight seal between the sealing case and around at least one port in the filtration cassette when installed in a filtration system. The sealing case may comprise two halves that mate together, and each half may be identical. The internal surface of the sealing case is flat or substantially flat.

A membrane-based separation device comprises multiple interconnected flat sheets of membrane bonded to a flexible film. The bonded films are bonded in a way to create an accordion or zig-zag shape. In certain embodiments, the first or upstream layer is affixed to a suitable housing, and the last or most downstream layer is also affixed to the suitable housing. The housing may contain an inlet port for the introduction of sample, and an outlet port for the removal of filtered sample. Flow through the segments is in parallel. Since the membranes are not folded or pleated, higher performance membranes (e.g., polysulfone based membranes with some degree of asymmetry) than those usable in pleated or folded systems can be used.

Filtering systems, methods, and devices, particularly adapted for apheresis of cellular bodies and more specifically for apheresis of circulating tumor cell bodies (CTCs) employs a cross-flow channel. Systems and methods as well as devices for such a system are described. Embodiments include a cylindrical filter that employs a thin micro-machined porous filter membrane with a regular array of pores and reliably pass blood while trapping CTCs.

A filtration assembly includes at least one membrane assembly, where the membrane assembly includes a membrane and at least one end cap device. The end cap device is defined in part by a longitudinal axis and extends from a first end to a second end along the longitudinal axis. The end cap device includes an intermediate profile between the first end and the second end, and the second end has a smaller inner diameter than the first end.

A filtration filter is suitable for performing cross-flow filtration by using a metallic porous membrane. A metallic porous membrane has a membrane portion for filtering filtration objects contained in a fluid and a held portion provided at its outer periphery. A first frame member and a second frame member hold the held portion of the metallic porous membrane there between. The held portion has a bent portion bent to a second principal surface side opposing a first principal surface of the membrane portion. The first frame member is in contact with the held portion at the first principal surface side of the metallic porous membrane. The second frame member is disposed at an inner side portion of the first frame member and is in contact with the held portion at the second principal surface side of the metallic porous membrane.

A method for lifting a membrane separation device immersed in liquid to be treated so as to obtain permeated liquid passed through a filtration membrane provides a method for lifting the membrane separation device in a visible state without lowering the liquid level of a treatment tank. The method includes injecting a gas into a predetermined region of the membrane separation device, thereby raising the membrane separation device by a buoyancy generated by the injected gas through the liquid to be treated, and engaging an engaging portion of a lifting apparatus with an engageable portion provided to an upper portion of the membrane separation device, thereby lifting up the membrane separation device. The predetermined region may be a space constituting a flow path for the permeated liquid permeated through the filtration membrane.