The present disclosure relates to a cassette assembly. An inlet cassette plate defines an inlet cassette inlet flow path and an inlet cassette outlet flow path. An outlet cassette plate is configured to be arranged in a stack with the inlet cassette plate. The outlet cassette plate defines an outlet cassette inlet flow path configured to be laterally aligned with the inlet cassette inlet flow path, and an outlet cassette outlet flow path configured to be laterally aligned with the inlet cassette outlet flow path. An inlet plug is configured to be inserted in the outlet cassette inlet flow path. An outlet plug is configured to be inserted in the inlet cassette outlet flow path. The inlet and outlet plugs are configured to be removable and reinsertable. A separation layer is disposed between the inlet cassette plate and the outlet cassette plate.

A membrane module includes a housing, a membrane structure housed in the housing, a sealing portion configured to seal a gap between the housing and the membrane structure, and a cooling portion configured to cool a portion of the housing in contact with the sealing portion.

In some embodiments thereof, the present invention describes TFF (Tangential Flow Filtration) filtration devices that utilize tubular membranes for the separation of cells and particles. These devices encompass several innovative features, including the use of membrane tubes with either circular or non-circular cross-sections. These tubes are closely surrounded by both tube housing and filter housing to regulate the pressure of the liquid exiting the filter housing. Additionally, the membrane tubes may feature internal cores within their lumens and/or structures along their inner walls. These internal features serve to regulate flow patterns and pressures within the tubes. One notable aspect of this invention is the inclusion of features on the tube housing or tube core that effectively regulate pressure resistance and feed flow patterns. These features lead to a reduction in the required recirculation rate and contribute to improved transmembrane pressure profiles, making these membrane filters highly effective for cell retention in cell culture and other applications. The patent also introduces various filter designs that incorporate tubular membranes into TFF filtration devices to achieve multiple goals, including a more consistent TMP (Transmembrane Pressure) profile for efficient separation, reduced recirculation rates to generate adequate shear rates, higher packing densities of membrane surface areas within the same filter design, and enhanced manufacturability and recyclability of the filters. Overall, this invention represents a significant advancement in the field of TFF filtration, offering innovative solutions for a wide range of applications in the separation of cells and particles.

A filter assembly adapted for insertion into an inner chamber of a pressure vessel, wherein the assembly includes: a spiral wound membrane module (2) comprising at least one membrane envelope (4) and feed spacer sheet (6) concentrically wound about a central permeate tube (8) extending along an axis (X) forming an inlet scroll face (30) and outlet scroll face (32) and a cylindrical outer peripheral surface (38), an end cap (33) having a surface (72) covering a portion of the inlet scroll face (30) and at least one opening (76) in the end cap surface (72) near the permeate tube for permitting fluid to flow through the inlet scroll face (30) and into the feed spacer sheet (6) of the module (2), and a brine seal (65) having a radially extending flexible lip (70) defining a maximum outer diameter adapted to engage the inner chamber of the pressure vessel; wherein the brine seal is sealed to the end cap (33).

A filter module has hollow fibers which are combined into fiber bundles having end face pottings. The pottings of the fiber bundles are received into a common end disk.

A process for producing nitrogen-rich air by feeding high temperature air at 150? C. or more to an air separation membrane module is described. After being placed at 175? C. for two hours, the air separation module exhibits a shape-retention ratio of 95% or more in one embodiment. The nitrogen-rich air can be fed to a fuel tank for an aircraft, for example.

The present invention relates to novel cartridges and modules for separation of fluid mixtures, especially for gas separation, to a process for production thereof and to a method of use thereof.

Proposed is a fuel cell membrane humidifier which includes a main housing, a hollow fiber membrane cartridge including a seal mount and a fixing layer, an inlet housing including a coupling portion, a seal ground portion, and a main chamber, an outlet housing including a coupling portion, a gas inflow port, a second chamber, and a cartridge insertion portion, a variable seal including a body portion, and a rib elastically transformed with respect to the body portion and being in close contact with the seal ground portion, and a back pressure passage communicating between the main chamber and the seal ground portion, wherein the ground pressure of the rib on the seal ground portion is formed to increase in correspondence to the pressure of dry air of the main chamber introduced through the back pressure passage when the dry air is supplied.

The present invention relates to novel cartridges and modules for separation of fluid mixtures, especially for gas separation, to a process for production thereof and to a method of use thereof.

A gas separation membrane module includes a seal between a higher pressure gas and a lower pressure gas. The seal includes a compressible sealing member in between sealing surfaces. At least one of the sealing surfaces has corrosion-resistant cladding provided over either low alloy steel or high alloy steel. The cladding reduce the possibility of a seal failure due to corrosion of low alloy or high alloy steel exposed to acid gases or condensed moisture containing acid gases dissolved therein while at the same not requiring that all surfaces of the membrane module exposed to acid gases be provided with cladding.