A piece of substrate material is formed under heat and pressure against a cavity into a shaped substrate sheet having one or more depressions. Two substrate sheets are bonded together to form a substrate wherein the one or more depressions form one or more interior channels. The substrate, if not formed with pre-coated substrate material, is coated with a dope and quenched to form a filtering membrane. A plurality of membranes may be placed side by side to form a bundle with permeating ends of the membrane, which are open to the one or more interior channels, separated by gaps or spacers. The bundle is connected to a header to produce a module. The module can be assembled into a cassette.

A molecular filtration device and method of use capable of filtering and purifying molecules of a particular characteristic, wherein the amount of molecule to be filtered may be in the nanogram range and may be dispersed in a relatively large volume of solution. The resultant elution may include a relatively high concentration of desired molecule, due to a relatively small volume.

The present invention is related to a new membrane cartridge system comprising hollow fiber membranes, a special new end cap for the production of the new cartridge, membrane separation devices comprising the new membrane cartridges and a process for manufacture of the new cartridges.

Provided is a filtration device exhibiting a high water treatment capacity and capable of increasing the longevity of a hollow-fiber filter, in a water purification device not requiring a purification material and requiring a high water treatment capacity. The filtration device (3) has: a housing case (15) having a water inlet unit and a water outlet unit arranged on one end side thereof; and a membrane module (17) provided inside this housing case (15). A first flow path (31) for causing raw water that has flowed in from the water inlet unit (21) to flow further to the other end side of the housing case (15) than the membrane module (17), and a second flow path (33) for causing the raw water that has flowed further to the other end side of the housing case (15) along this first flow path (31) to pass through the membrane module (17) and flow to the water outlet unit (23) are provided inside the housing case (15). A spacer (19) is provided on the upstream side of the membrane module (17) in the second flow path (33).

The disclosure relates to a membrane leaf packet, and a spiral membrane element including a plurality of such membrane leaf packets, including such elements exhibiting enhanced sanitary properties. Such membrane elements can be used for filtration, for example, in food-related fields, including filtering dairy, sugar and/or other liquid streams.

A gas-permeable well for use with a bioreactor may include a reinforced gas-permeable membrane. The gas-permeable membrane may include an integrated reinforcing structure such as a stainless steel mesh or perforated screen, and may include an integrated gasket or O-ring, or other regions of increased thickness. A sensor brought into close proximity to the reinforced gas-permeable membrane may take an indirect measurement of a condition of process medium on the other side of the gas-permeable membrane, such as a measurement of dissolved oxygen or carbon dioxide.

A housing (30) of a hollow-fiber membrane module (101) is so configured as to have a small-diameter part (3B) having an inner diameter smaller than an inner diameter of a flow regulation cylinder (9) facing a part of the housing (30) on which a nozzle (8) is provided, and which is arranged on a lower side than a lower end of the flow regulation cylinder (9) in an axial direction of the hollow-fiber membrane module (101); or the flow regulation cylinder (9) is so configured as to have a small-diameter part (9G) which has an inner diameter smaller than the inner diameter of the flow regulation cylinder (9) facing the part of the housing (30) on which the nozzle (8) is provided, and which is arranged on a lower side than the existing region of the flow regulation holes (10) in the axial direction of the hollow-fiber membrane module (101).

The gas separation membrane element contains a gas separation membrane, and a sealing portion for preventing mixture of a source gas and a specific gas permeated through a gas separation membrane. The gas separation membrane has a first porous layer including a porous membrane, and a hydrophilic resin composition layer disposed on the first porous layer. The sealing portion is a region in which a cured material of a sealant penetrates in at least the first porous layer in the gas separation membrane, and a thermal expansion coefficient A of the sealing portion and a thermal expansion coefficient B of a material forming the first porous layer satisfy a relation (I):

0.35A/B1.0 (I).

A process for producing nitrogen-rich air by feeding high temperature air at 150 C. or more to an air separation membrane module is described. After being placed at 175 C. for two hours, the air separation module exhibits a shape-retention ratio of 95% or more in one embodiment. The nitrogen-rich air can be fed to a fuel tank for an aircraft, for example.

A spiral wound membrane module adapted for hyperfiltration and including at least one membrane envelope and feed spacer sheet wound about a central permeate tube to form an inlet and outlet scroll face and an outer periphery, wherein the feed spacer sheet includes: i) a feed entrance section extending along the permeate collection tube from the inlet scroll face toward the outlet scroll face, ii) a feed exit section extending along the outer periphery from the outlet scroll face toward the inlet scroll face, and iii) a central feed section located between the feed entrance section and the feed exit section; and wherein the feed entrance section has a median resistance to flow in a direction parallel to the permeate collection tube that is less than 25% of the median resistance to flow of the central feed section in a direction perpendicular to the permeate collection tube.