The reverse osmosis centrifuge converts rotational energy into fluid velocity and conserves the energy placed into the concentrate. As concentrate travels back towards the center of the reverse osmosis centrifuge, the velocity of the fluid is converted into rotational force, thus conserving energy. To accomplish this, the reverse osmosis centrifuge includes a stationary cylindrical housing having a vacuum chamber and a vacuum pump for generating vacuum pressure in the vacuum chamber, a driveshaft coupled to a membrane cylinder rotatable within the stationary cylindrical housing, the membrane cylinder having a plurality of vertical desalination membranes, and an energy recovery turbine. The reverse osmosis centrifuge can be placed on the concentrate or waste stream outlet of a desalination or reverse osmosis facility to increase freshwater production. Through using the methods described above, plant water production can be increased up to 40%, which in turn has a dramatic effect on plant profitability.

The present disclosure provides a cell separation apparatus for a bioreactor. The cell separation apparatus may be disposed outside the bioreactor and in fluid connection with the bioreactor, the cell separation apparatus may be in a shape of a box body, the cell separation apparatus may include a liquid buffer device including a first liquid cavity disposed in the box body; a filter device including a filter channel and a filter membrane disposed in the box body, the filter membrane may be disposed above the filter channel; and a first liquid channel may be configured in the box body to facilitate a fluid communication between the first liquid cavity and the filter channel. A power system for filtering and microfluidic channels are integrated in the cell separation apparatus that is of a box shape, thereby reducing the volume and production cost thereof.

A gas trap assembly including a base connector housing including an inflow port and an outflow port, a reservoir fluidly connecting the inflow port to the outflow port, and a grooved porous media located within the reservoir. The grooved porous media including a plurality of grooves and composed of a material having a plurality of pores of a selected size. The grooved porous media fluidly divides the reservoir into two portions in such a way that a working fluid flowing from the inflow port to the outflow port must flow through the plurality of grooves and the plurality of pores of the grooved porous media. The plurality of grooves and the plurality of pores are configured to prevent gas from passing through the grooved porous media.

Presteralized manifolds are provided which are designed for sterile packaging and single-use approaches. Disposable tubing and flexible-wall containers are assembled via aseptic connectors. These manifolds are adapted to interact with other equipment which can be operated by a controller which provides automated and accurate delivery of biotechnology fluid. The manifold also can be used in conjunction with one or more sensors such as pressure and conductivity sensors that interact with the controller or are connected to a separate user interface. An aseptic environment obtains avoiding or reducing cleaning and quality assurance procedures.

The present disclosure provides a cell separation apparatus for a bioreactor. The cell separation apparatus may be disposed outside the bioreactor and in fluid connection with the bioreactor, the cell separation apparatus may be in a shape of a box body, the cell separation apparatus may include a liquid buffer device including a first liquid cavity disposed in the box body; a filter device including a filter channel and a filter membrane disposed in the box body, the filter membrane may be disposed above the filter channel; and a first liquid channel may be configured in the box body to facilitate a fluid communication between the first liquid cavity and the filter channel. A power system for filtering and microfluidic channels are integrated in the cell separation apparatus that is of a box shape, thereby reducing the volume and production cost thereof.

Methods of filtering a liquid feed are disclosed. In one version, the method comprises passing a liquid feed through a single pass tangential flow filtration (SPTFF) system and recovering the retentate and permeate from the system in separate containers without recirculation through the SPTFF system. In another version, the method of filtering a liquid feed, comprises passing a liquid feed through a tangential flow filtration (TFF) system, recovering permeate and a portion of the retentate from the system in separate containers without recirculation through the TFF system, and recirculating the remainder of the retentate through the TFF system at least once. The methods can be performed using an SPTFF or a TFF system that comprises manifold segments to serialize the flow path of the feed and retentate without requiring diverter plates.

The present invention relates to a double pipe and, more specifically, to a double pipe for uniformly distributing a flow, which can distribute as uniformly as possible a flow which should be distributed toward branch pipes thereof. The present invention relates to a double pipe for uniformly distributing a flow, and can be applied to a seawater desalination device or a water purification device using a membrane and can be thus employed in the water treatment plant industry.

A filter device includes an inlet manifold, an outlet manifold and membrane filter units. Each membrane filter unit has an inlet opening for a fluid flow to be processed, a first outlet opening for a retentate portion of the fluid flow, and a second outlet opening for a remaining portion of the fluid flow. Each inlet opening is fluidly connected to the inlet manifold, and each first outlet opening is fluidly connected to the outlet manifold. The two membrane filter units are staggered and are not axially aligned with respect to each other. One of the membrane filter units is fluidly connected to the inlet manifold and to the outlet manifold via a first set of conduits, and the other membrane filter unit is fluidly connected to the inlet manifold and to the outlet manifold via a second set of conduits.

Filter arrangements comprising a plurality of radially arranged filters, each filter comprising a plurality of arms, each arm comprising a hollow tube having porous side wall, each hollow tube having an open first end and an open second end, and a tube inner fluid channel having an inner diameter; the filter further including a first tube connector, comprising a first hollow body having porous side walls and a first hollow body inner diameter, connected to, and in fluid communication with, the hollow tubes, and a second tube connector, comprising a second hollow body having a second hollow body inner diameter, connected to, and in fluid communication with, the first hollow body, and filter devices including filter arrangements, and methods of use are disclosed.

A hollow fiber module includes hollow fiber cartridges. A port receives a second solution to be treated in a shell side volume and another port for discharging the treated second solution. A first end cap has an inlet for a first solution and a distributer for distributing the first solution to a first end of the hollow fiber cartridges. A second end cap has a collector for collecting the treated first solution from the second end of the hollow fiber cartridges and an outlet for the treated first solution. A first connector has an inlet for the second solution and a distributer for distributing the second solution to a port of the hollow fiber cartridges. A second connector has a collector for collecting the treated second solution from the other port of the hollow fiber cartridges and an outlet for the treated second solution.