Systems and methods provide automated parameter assurance features and results for consumables used in bioprocessing and particularly for purifying, filtering, harvesting and collecting bioprocessing fluids. Consumables having these features are sized, shaped, configured and constructed to interface with and be a component of such a bioprocessing system that includes a multi-use component or device with which it operatively engages such as by docking, engagement with a connector or other approach that allows for insertion and removal of the consumable. The consumable may be a component having a single-use life or a limited life. Each consumable has a median by which information, which can include use limits and specifications, is associated with that specific consumable, and those limits and specifications are communicated to the multi-use component which indicates any inappropriateness for use with the multi-use component.

An automated modular filtration system, particularly for low volume tangential flow filtration processes, comprises a plurality of filtration modules formed as separate assemblies and at least one control unit for jointly controlling filtration processes of individual filtration units. Each filtration module contains at least one individual filtration unit for executing a filtration process independent of the other filtration units, first input ports for receiving a first type of fluids, second input ports for receiving a second type of fluids, and exit ports for outputting unused system fluids. First type fluids are process fluids are specific to the filtration processes executed in individual filtration units. Second type fluids are system fluids not specific to filtration processes executed in the individual filtration units. The second input and exit ports establish inter-module connections so system fluids can be forwarded from one filtration module to an adjacent filtration module of the filtration system.

A filter module for a gravity-based water purification device is provided. A filter module for a gravity-based water purification device, according to one embodiment of the present invention, comprises: a support frame including a loop-shaped edge member, which includes an empty space of which both sides are open, and a dividing member, which is coupled to the edge member so as to enable the empty space to be divided into a plurality of storage spaces; a pair of filtering members which are formed in a plate shape having a predetermined area, and which are coupled to the support frame so as to enable filtered water to be produced from raw water moving from the outside toward the plurality of storage spaces; and water-collecting ports for discharging, to the outside, the filtered water stored in the plurality of storage spaces, wherein the plurality of storage spaces communicate with each other through at least one communication passage formed at the dividing member.

A ceramic membrane filtration assembly includes a housing and a membrane assembly. The membrane assembly includes at least one membrane with channels therein. A first inner end cap device is disposed within the housing and is coupled with the membrane assembly. The housing has a bypass near an outer perimeter of the first inner end cap device, the first inner end cap device has an inner port, the inner port fluidly coupled with the channels of the membrane, where the bypass includes a space between the housing and the first inner end cap device. A first outer end cap device is coupled with the first inner end cap device; the first outer end cap device has a first port and a second port, where the first port is fluidly separate from the second port, and the first port is fluidly coupled with the inner port.

The invention relates to filtration system (20), comprising a tank (40) filled at least partly with water to be filtered, and at least one filtration module (30), the at least one filtration module (30) comprising at least one filter membrane (10) for filtering the water comprising a substrate (12) which is penetrated by at least one capillary (16), and at least one filtrate pipe (32) for drawing filtered water out of the tank (40), whereat the at least one filtration module (30) is arranged in the tank (40) such that the at least one filter membrane (10) is submerged at least partly in the water to be filtered. The at least one filtration module (30) is designed and arranged such that water to be filtered flows into the at least one capillary (16) and from the at least one capillary (16) through the substrate (12) into the filtrate pipe (32). The invention also relates to a method for filtering water by means of a filtration system (20) according to the invention, whereat the water to be filtered is drawn into the at least one capillary (16) and from the at least one capillary (16) through the substrate (12) into the filtrate pipe (32) and from the filtrate pipe (32) out of the tank (40).

The invention relates to liquid purification systems with filtration membranes application, intended for liquid purification and desalination, predominantly water from different recourses, including drinking water, process medium, drainage, drinks and other liquids in household or technical conditions, in country and suburban and garden plots. Liquid purification system comprising raw liquid supply line, liquid purification unit, connected to raw liquid supply line, purified liquid line, connected to purified liquid outlet of the liquid purification unit, and drainage liquid line, connected to drainage liquid outlet of the liquid purification unit, besides liquid purification unit comprises at least two membranes in a shells and connected to each other through two collectors, characterized in that collector is formed by at least two elements, communicating between each other through the adapter plugs and connected between each other with fastener.

Affinity chromatography devices that include a fibrillated heat treated polymer membrane that contains inorganic particles having a spherical shape and a particle size distribution that has a D90/D10 less than or equal to 3 are disclosed. A blend or combination of spherical inorganic particles having a nominal particle size from about 5 microns to about 20 microns may be utilized. Also, the devices have a hydraulic permeability from about 200(10.sup.12 cm.sup.2) to about 700(10.sup.12 cm.sup.2). The affinity chromatography devices have a dynamic binding capacity (DBC) greater than 35 mg/ml at 10% breakthrough at a residence time of 20 seconds. Additionally, the affinity chromatography devices have a cycling durability of at least 100 cycles without exceeding an operating pressure of 0.3 MPa. Manifolds containing multiple affinity chromatography devices and manifolds in a parallel configuration are also disclosed.

A filter device includes an inlet manifold, an outlet manifold and membrane filter units. Each membrane filter unit has an inlet opening for a fluid flow to be processed, a first outlet opening for a retentate portion of the fluid flow, and a second outlet opening for a remaining portion of the fluid flow. Each inlet opening is fluidly connected to the inlet manifold, and each first outlet opening is fluidly connected to the outlet manifold. The two membrane filter units are staggered and are not axially aligned with respect to each other. One of the membrane filter units is fluidly connected to the inlet manifold and to the outlet manifold via a first set of conduits, and the other membrane filter unit is fluidly connected to the inlet manifold and to the outlet manifold via a second set of conduits.

Hemofilters for in vivo filtration of blood are disclosed. The hemofilters disclosed herein provide an optimal flow of blood through the filtration channels while maintaining a pressure gradient across the filtration channel walls to enhance filtration and minimize turbulence and stagnation of blood in the hemofilter.

A vacuum manifold for filtration microscopy includes a manifold top having multiple openings, and a capture membrane positioned above and spaced apart from the manifold top, where the capture membrane is configured to deflect into contact with a surface of the manifold top when a negative pressure is applied to the multiple openings. A method for filtration microscopy includes the steps of providing a vacuum manifold including a manifold top having a plurality of openings, and a capture membrane positioned above and spaced apart from the manifold top; applying sample drops to sample spots on the membrane, the sample spots positioned above the plurality of openings; applying a negative pressure to the openings such that the capture membrane contacts a surface of the manifold top; and optically imaging particulates on the capture membrane.