The specification discloses a portable dialysis machine having a detachable controller unit and base unit. The controller unit includes a door having an interior face, a housing with a panel, where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The base unit has a planar surface for receiving a container of fluid, a scale integrated with the planar surface, a heater in thermal communication with the planar surface, and a sodium sensor in electromagnetic communication with the planar surface. Embodiments of the disclosed portable dialysis system have improved structural and functional features, including improved modularity, ease of use, and safety features.

A method of filtering a liquid feed is described, comprising passing a liquid feed through a single pass tangential flow filtration (SPTFF) system and recovering the retentate and permeate from the system in separate containers. A method of filtering a liquid feed is also described comprising passing a liquid feed through a tangential flow filtration (TFF) system, recovering permeate and a portion of the retentate from the system in separate containers without recirculation through the TFF system, and recirculating the remainder of the retentate through the TFF system at least once. The methods of the invention can be performed using an SPTFF or a TFF system that comprises manifold segments to serialize the flow path of the feed and retentate without requiring diverter plates.

A method of operating an immersed microporous membrane module includes a step of monitoring membrane performance to sense the onset of sludging in the module. Differences in permeability between permeation in backwashes, or trends in permeability during backwashing and permeability during permeation, or both, are monitored. Solid deposits formed during the onset of sludging may be removed with an in situ de-sludging process. For example, the deposits may be removed by stopping permeation while aerating the module, optionally at an increased rate. At other times, the module is optionally aerated while permeate is withdrawn at an aeration rate correlated to flux. The method may be used in particular with a membrane module having parallel textured flat sheet membranes suspended between a pair of vertically oriented headers. An aerator may be made from an open bottomed channel having an array of holes rising and concentrated towards the center of the channel.

A water drain management apparatus used in clinical facility (43) or other facility includes a manifold plumbing fitting (32, 272, 384). The fitting includes a plurality of drain outlet connections for water discharge devices (40, 42, 222, 226, 230, 234). Such water discharge devices may include devices such as autoclaves, sterilizers, cleaners, washers, filters, humidifiers, condensing devices and other devices used in the facility. A plurality of drain fitting openings in the body of the fitting are connectable to respective water discharge devices, and openings that are not utilized are closable with plugs. Some manifold fittings (272, 344, 384, 482) include an air gap opening (288, 360, 392, 530). These configurations provide an air gap that prevents contamination due to back flow of water within the fitting reaching water discharge devices or the body inlet of the manifold fitting.

Stack assembly comprising a hollow external housing having a central axis, the external housing extending from a first end to a second end and enclosing a housing space, and a membrane stack comprising a plurality of membranes, wherein the membrane slack is positionable inside the external housing and a number of side plates extending substantially parallel to the central axis, wherein each side plate of the number of side plates is associated with a side of the membrane stack and extending along the associated side and a number of sealing connectors that extend substantially parallel to the central axis and adjacent with an inner surface of the external housing, wherein each sealing connector of the number of sealing connectors is configured to connect two side plates to each other, wherein the sealing connectors and the side plates cooperate to form an enclosing structure, and wherein, in use of the stack assembly, the enclosing structure encloses the membrane stack. The invention also relates to a method for assembling a stack assembly and a method for generating energy or performing an electrodialysis process.

A vacuum manifold for filtration microscopy includes a manifold top having multiple openings, and a capture membrane positioned above and spaced apart from the manifold top, where the capture membrane is configured to deflect into contact with a surface of the manifold top when a negative pressure is applied to the multiple openings. A method for filtration microscopy includes the steps of providing a vacuum manifold including a manifold top having a plurality of openings, and a capture membrane positioned above and spaced apart from the manifold top; applying sample drops to sample spots on the membrane, the sample spots positioned above the plurality of openings; applying a negative pressure to the openings such that the capture membrane contacts a surface of the manifold top; and optically imaging particulates on the capture membrane.

A filtration cassette including a multilaminate array of sheets including filter sheets alternating with permeate sheet members and retentate sheet members, and a cross-flow filter device comprising a multiplicity of stacked filtration cassettes of such type. The improvements associated with the filtration cassettes described herein include, but are not limited to, at least one of: reinforced inlet(s) providing for longevity and improved cleanability of the cassettes; spacer permeate screens to limit throughput restriction; stainless steel or otherwise stiffened permeate sheets to prevent movement and increase flux; and stainless steel permeate sheets that can be used with ultrasonic transmission to minimize fouling of the filter sheets and extend cleaning cycles. Advantageously, the filtration cassettes are more resistant to higher temperatures than the filtration cassettes of the prior art.

A manifold for domestic water purification systems having flow paths that can be redirected without having to change the physical structure of the manifold or water purification systema structure to assist with proper installation of specific filter cartridges, a memory reader for processing data relating to the state of the filter cartridges, a hinge system to allow for easier installation/removal of new and replacement filter cartridges, and a flow path structure to assist in adding accessories to the water filtration system without requiring a modification to the manifold structure.

Provided is a spiral membrane module which is suitable for being set up in the vertical direction since at one end of its pressure vessel, the supply of feed liquid and the discharge of concentrated liquid can be attained.

The invention relates to filtration system (20), comprising a tank (40) filled at least partly with water to be filtered, and at least one filtration module (30), the at least one filtration module (30) comprising at least one filter membrane (10) for filtering the water comprising a substrate (12) which is penetrated by at least one capillary (16), and at least one filtrate pipe (32) for drawing filtered water out of the tank (40), whereat the at least one filtration module (30) is arranged in the tank (40) such that the at least one filter membrane (10) is submerged at least partly in the water to be filtered. The at least one filtration module (30) is designed and arranged such that water to be filtered flows into the at least one capillary (16) and from the at least one capillary (16) through the substrate (12) into the filtrate pipe (32). The invention also relates to a method for filtering water by means of a filtration system (20) according to the invention, whereat the water to be filtered is drawn into the at least one capillary (16) and from the at least one capillary (16) through the substrate (12) into the filtrate pipe (32) and from the filtrate pipe (32) out of the tank (40).