A filtering device is for obtaining a chemical liquid by purifying a liquid to be purified and has an inlet portion, an outlet portion, a filter A, a filter B different from the filter A, and a flow path extending from the inlet portion to the outlet portion, in which the filter A and the filter B are arranged in series between the inlet portion and the outlet portion and have, and the filter A is selected from the group consisting of predetermined filters A1, A2, and A3.

Improved methods for the manufacture of pharmaceutical compositions comprising at least one surfactant, involving prefiltration of the surfactant prior to formulation into final products.

The invention relates to the field of membrane gas separation. A method of removing components of gas mixtures which is based on passing the components of a gas mixture through a nanoporous membrane and subsequently selectively absorbing them with a liquid absorbent that is in contact with the nanoporous membrane, wherein to prevent the gas from getting into the liquid phase of the absorbent and the liquid phase of the absorbent from getting into the gas phase, a nanoporous membrane with homogeneous porosity (size distribution less than 50%) and a pore diameter in the range of 5-500 nm is used, and the pressure differential between the gas phase and the liquid absorbent is kept below the membrane bubble point pressure. An acid gas removal performance of more than 0.3 nm.sup.3/(m.sup.2 hour) in terms of CO.sub.2 is achieved at a hollow-fiber membrane packing density of up to 3200 m.sup.2/m.sup.3, which corresponds to a specific volumetric performance of acid gas removal of up to 1000 nm.sup.3 (m.sup.3 hour). The technical result is that of providing effective extraction of undesirable components from natural and process gas mixtures.

A virus removal membrane is formed from a hydrophilized synthetic polymer, in which, when a solution containing gold colloids having a diameter of 20 nm is applied through a primary surface to the virus removal membrane to allow the virus removal membrane to capture the gold colloids for measurement of brightness in a cross section of the virus removal membrane, a value obtained by dividing a standard deviation of a value of an area of a spectrum of variation in the brightness by an average of the value of the area is 0.01 or more and 1.5 or less; and a thickness of a portion, where gold colloids having a diameter of 20 nm or more and 30 nm or less are captured, in the cross section of the virus removal membrane in a wet state is 10 m or more and 30 m or less.

Asymmetric composite membranes and methods for their preparation are disclosed. The membranes comprise a cross-linked poly(vinyl alcohol) polymer coated on a film of cross-linked sulfonated poly(ether ether ketone) adhered to a sheet of hydrophilicitized microporous polyolefin. The microporous polyolefin is typically microporous poly(ethylene). The membranes have improved selectivity with the regard to the rejection of solutes in reverse osmosis and ultrafiltration applications.

Provided is a porous membrane which has a high water permeability performance, a high blocking performance, and a durability performance against loads of long-term and high operation pressures, which are suitable for filtering applications. The porous membrane includes one surface to be on a side of a filtrate; and the other surface to be on a side of a liquid to be filtered, wherein a surface pore diameter index of the one surface is 2.5 or more, the surface pore diameter index being determined by dividing a pore diameter in a top surface by a pore diameter in a second top surface.

The problem addressed by the present invention is to provide a separation membrane with superior permeation performance and separation performance and having few occurrences of defects. The present invention relates to a separation membrane wherein: the separation membrane has a layer (I) with a thickness of 0.5-100 m; letting, in a cross-section in the direction of thickness of the layer (I), region a be a region with a depth of 50-150 nm from a surface (surface A), region b a region with a depth of 50-150 nm from the other surface (surface B), and region c a region with a thickness of 100 nm where the depth from both surfaces is the same, the average pore diameter Pa for region a and the average pore diameter Pb for region b are both 0.3-3.0 nm and the average pore diameter Pc for region c is 3.0 nm or less; and the percentage of open area Ha for region a, the percentage of open area Hb for region b, and the percentage of open area Hc for region c satisfy the following equations. 2Hc<Ha 2Hc<Hb

The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.

Grafted, asymmetric, porous, ultra high molecular weight polyethylene membranes having a bubble point between about 5.38 bar (78 psi) and 11.03 bar (160 psi) are disclosed. Monomers are grafted to the porous polymeric membrane surfaces, the monomers having one or more of neutral groups or ion exchange groups grafted to one or more surfaces of the membrane. A combination of two photoinitiators can be used to graft the monomers to the asymmetric, porous, ultra high molecular weight membrane resulting in grafted microporous membranes that have water flow rates that are at least 50% of the water flow rate of an ungrafted, asymmetric, porous ultra high molecular weight polyethylene membrane. The grafted membrane also wets in water.

A virus removal membrane includes cellulose, and a primary-side surface through which the protein-containing solution is to be applied and a secondary-side surface from which a permeate that has permeated the virus removal membrane is to be flowed, wherein a bubble point is 0.5 MPa or more and 1.0 MPa or less; and when a solution containing gold colloids having a diameter of 30 nm is applied through the primary-side surface to the virus removal membrane to allow the virus removal membrane to capture the gold colloids for measurement of brightness in a cross section of the virus removal membrane, a value obtained by dividing a standard deviation of a value of an area of a spectrum of variation in the brightness by an average of the value of the area of the spectrum of variation in the brightness is 0.01 or more and 0.30 or less.