The disclosure herein relates to a microfluidic emulsification device capable of being injection molded. The device may be used for digital droplet polymerase chain reaction (ddPCR). The emulsification device comprises: (a) a cylindrical outer part (4) with two open ends; (b) a cylindrical inner part (1) with a solid bottom and having a circumference sufficient to allow the inner part to be nested within the outer part of the emulsification device, wherein the inner part and the outer part are capable of sliding freely; (c) at least one groove on an interior surface of the outer part or on an exterior surface of the inner part, the groove having a height greater than a gap between the outer part and the inner part when nested; (d) at least one hole (3) in the inner part adjacent to the solid bottom; (e) a radial distribution channel (2) on the interior surface of the outer part or on the exterior surface of the inner part; and (f) a radial nozzle channel at the base of the interior surface of the outer part or at the base of the exterior surface of the inner part.

The disclosure herein relates to a microfluidic emulsification device capable of being injection molded. The device may be used for digital droplet polymerase chain reaction (ddPCR). The emulsification device comprises: (a) a cylindrical outer part (4) with two open ends; (b) a cylindrical inner part (1) with a solid bottom and having a circumference sufficient to allow the inner part to be nested within the outer part of the emulsification device, wherein the inner part and the outer part are capable of sliding freely; (c) at least one groove on an interior surface of the outer part or on an exterior surface of the inner part, the groove having a height greater than a gap between the outer part and the inner part when nested; (d) at least one hole (3) in the inner part adjacent to the solid bottom; (e) a radial distribution channel (2) on the interior surface of the outer part or on the exterior surface of the inner part; and (f) a radial nozzle channel at the base of the interior surface of the outer part or at the base of the exterior surface of the inner part.

A stirrer is provided that can more efficiently achieve shearing applied, by an action of an intermittent jet flow, to a fluid to be processed. The stirrer concentrically includes a rotor including a blade, a partition wall, and a screen, wherein: the screen includes a plurality of slits in a circumferential direction thereof and screen members located between the adjacent slit; by rotating at least the rotor of the two components, the fluid to be processed is discharged from the inside to the outside of the screen as the intermittent jet flow through the slit of the screen; the screen has a cylindrical shape having a circular cross section; an opening of the slit provided on the inner wall surface of the screen is used as an inflow opening; openings of the plurality of slits provided on the outer wall surface of the screen are used as outflow openings; and the width of the outflow openings in the circumferential direction is set to be smaller than the width of the inflow opening in the circumferential direction.

Methods and systems for sorting particles are provided. Methods and systems for sorting cell beads are provided. In some cases, cell beads may be sorted from particles unoccupied with cell derivatives. In some cases, singularly occupied cell beads may be sorted from unoccupied particles and multiply occupied cell beads.

A molded body is produced from a molding material including a continuous phase and a dispersed phase by a three-dimensionalization step, a curing step, and a peeling step. The continuous phase of the molding material is a water phase containing a curable compound. In the three-dimensionalization step, the molding material is placed in a container. In the curing step, the curable compound is cured to form a cured product after the three-dimensionalization step. In the peeling step, the container and the cured product are separated after the curing step. In the dispersed phase removal step, the dispersed phase of the cured product is removed after the curing step.

The invention relates to a mixing system for producing a cosmetic product. The invention also relates to a capsule (7, 8) containing a cosmetic compound. The mixing system allows the production of a cosmetic product from capsules (7, 8) comprising the raw materials required for the composition of such a cosmetic product, that is the cosmetic texturising agent, the cosmetic active substance and, as required, a cosmetic perfume. The invention is applicable in the cosmetic industry.

The invention relates to a mixing system for producing a cosmetic product. The invention also relates to a capsule (7, 8) containing a cosmetic compound. The mixing system allows the production of a cosmetic product from capsules (7, 8) comprising the raw materials required for the composition of such a cosmetic product, that is the cosmetic texturising agent, the cosmetic active substance and, as required, a cosmetic perfume. The invention is applicable in the cosmetic industry.

A method of producing a pharmaceutical gel emulsion, wherein the emulsion is an oil-in-water gel emulsion, comprising the steps of forming an oil-in-water emulsion comprising at least one pharmaceutically acceptable oil, at least one aqueous phase, at least one osmotic agent, at least one emulsifying agent, mixing a gelling polysaccharide with the oil-in-water emulsion and allowing the resulting mixture to form the pharmaceutical gel emulsion, optionally mixing an bioactive agent into the pharmaceutical gel emulsion.

The invention provides a method for validating the functioning of an apparatus with a static mixing device for mixing two liquid streams for producing nanoparticles. The static mixing device may be a jet impingement reactor. The method is based on the use of PLA, PLG or PLGA for producing polymeric nanoparticles with highly reproducible particle sizes. The invention further provides kits and liquid compositions for carrying out the method.

A method for producing a synthetic rubber, the method including: an emulsification step of continuously feeding a solution or a dispersion of a synthetic rubber obtained by dissolving or dispersing the synthetic rubber in an organic solvent and an aqueous solution of an emulsifier to a mixer and mixing to continuously obtain an emulsion; a first removal step of removing the organic solvent from the emulsion continuously obtained in the emulsification step in a container while the emulsion is continuously transferred to the container regulated to a pressure condition of 700 to 760 mmHg; and a second removal step of removing the organic solvent from the emulsion that has undergone the first removal step under a pressure of less than 700 mmHg.