A portable system for producing a formulation comprising lipid nanoparticle (LNP)-encapsulated RNA includes: a first sub-system comprising multiple drug substance formulation modules, the first sub-system comprising: a transcription module for forming an RNA solution via in vitro transcription; and a second sub-system operatively downstream of the first sub-system comprising multiple drug product formation modules, the second sub-system comprising: an LNP formulation module for producing a first RNA-LNP preparation from the RNA solution, wherein each of the transcription module and the LNP formulation module is contained within a separate standard shipping container.

A flow reactor has a module having a process fluid passage with an interior surface, a portion of the passage including a cross section along the portion having a cross-sectional shape, and a cross-sectional area with multiple minima along the passage. The cross-sectional shape varies continually along the portion and the interior surface of the portion includes either no pairs of opposing flat parallel sides or only pairs of opposing flat parallel sides which extend for a length of no more than 4 times a distance between said opposing flat parallel sides along the portion and the portion contains a plurality of obstacles distributed along the portion.

A decomposition tube for an exhaust treatment system includes a housing with a housing wall that defines an exhaust flow path for exhaust; a reductant delivery mechanism coupled to the housing and having a nozzle configured to deliver a spray of reductant into the exhaust flow path; and a mesh device with a mounting element mounted on the housing wall and a mesh basket secured to the mounting element proximate to the nozzle to enclose and intercept the spray such that effectively all of the reductant passes through the mesh basket and into the exhaust flow path prior to impinging on the housing wall.

The mixing nozzle has a throat section, a diffuser section, a gas nozzle section, a first liquid suction port, a liquid nozzle section, a second liquid suction port, a baffle plate, and a jetting port. The first liquid suction port liquidly absorbs the solution in the water storage pool from a side of the gas nozzle section toward the gas nozzle tip. The liquid nozzle section extends to the downstream side of the gas nozzle section with intervening the first liquid suction port. The second liquid suction port liquidly absorbs the solution in the water storage pool from a side of the liquid nozzle section toward the liquid nozzle tip. The baffle plate is provided such that the mixed flow mixed in the diffuser section collides in front of a downstream end of the diffuser section, and divides and reverses the mixed flow.

The invention relates to a carbonized water dispensing device (1) provided with a carbonized water conditioning chamber (2), which conditioning chamber (2) is provided downstream of the carbonator (7) and upstream of the carbonized water dispensing outlet (5), for receiving a mixture of carbonized water mixed with unresolved CO2, which conditioning chamber (2) is dimensioned to hold a single serve of carbonized water with a headspace, and which carbonized water conditioning chamber (2) is provided with an outlet valve (17) and a gas outlet (18). According to the invention, the carbonized water dispensing device (1) is configured to, upon receiving a beverage dispensing order, provide the empty carbonized water conditioning chamber (2) with a single serve volume of carbonized water, and hold the single serve of carbonized water prior to dispensing the single serve volume of carbonized water.

Systems and methods to obtain a desired rheology of drilling mud are described herein. Embodiments generally include a hollow tubular body coupled to, and including, numerous shearing elements configured to facilitate achievement of such desired rheology.

A flow reactor has a module having a process fluid passage with an interior surface, a portion of the passage including a cross section along the portion having a cross-sectional shape, and a cross-sectional area with multiple minima along the passage. The cross-sectional shape varies continually along the portion and the interior surface of the portion includes either no pairs of opposing flat parallel sides or only pairs of opposing flat parallel sides which extend for a length of no more than 4 times a distance between said opposing flat parallel sides along the portion and the portion contains a plurality of obstacles distributed along the portion.

An exhaust system for a diesel engine, includes an exhaust passage adapted to be attached to the diesel engine. A diesel oxidation catalyst is provided in the exhaust passage along with a selective catalyst reduction device disposed downstream from the diesel oxidation catalyst. A diesel exhaust fluid mixing system includes a diesel exhaust fluid injection nozzle and a mixing device defining a single inlet opening and a single outlet opening connected to one another by a partial spiral flow passage. The diesel exhaust fluid injection nozzle injects diesel exhaust fluid directly into the inlet opening of the partial spiral flow passage.

The invention relates to an apparatus (2) for mixing powdery baking ingredients with water. The apparatus (2) comprises a mixing chamber (4) which is inclined at a gradient and is preferably vertical, which has in an upper head region (6) at least one opening (8) for powdery baking ingredients falling into the mixing chamber (4) and in which there is arranged at least one nozzle (10) from which water (12) is ejected at a pressure of at least 30 bar from at least one nozzle opening (14). The nozzle opening (14) is directed at a mechanical obstruction (16) within the mixing chamber (4). Water (12) spraying out of the nozzle opening (14), together with the supplied baking ingredients, impacts the obstruction (16) in an impact region (20). Below the mixing chamber (4) there is arranged a container (24) which is provided with a cover (22) and which is connected, in a dough-conveying manner, to a discharge opening (26) of the mixing chamber (4). The apparatus has a suction device (32) for baking ingredient dust from the container (24), which has a suction opening (34) on the container (24), an inlet opening (36) into the mixing chamber (4) and a recycling duct (38) that connects the suction opening (34) to the inlet opening (36). Thus, the suction opening (34) is arranged in the head region (40) of the container (24) and the inlet opening (36) is arranged above the impact region (20) in the mixing chamber (4).

A burner includes a first tube portion formed with an ejection port; a second tube portion that extends in the first tube portion toward the ejection port and to which gaseous mixture flows in from a side opposite to the ejection port; a third tube portion arranged in the first tube portion and including an open end positioned on the ejection port side; a closing portion that closes the open end; a coupling wall portion that closes a gap between the first tube portion and the second tube portion; a partition wall that is coupled to the first tube portion and the third tube portion, the partition wall being formed with a communication path; and an igniting portion that is arranged on the ejection port side with respect to the partition wall.