The present set of embodiments relate to a bioproduction system, method, and apparatus for creating a scalable bioreactor system. Specifically, the present set of embodiments enable the determination of bioreaction performance characteristics of a commercial scale by matching operational parameters between a small test scale bioreaction to that of a commercial scale bioreaction. The system and methods do not rely on simply making bioreactor apparatuses across scales the same dimensionally which would not account for differences in fluid dynamic properties between very small to very large volumes, but requires tuning of a variety of systems (mixing assembly, sparger system, and headspace airflow system) in conjunction with one another to achieve predictive outcomes.

A fluid heating system includes a tank assembly having an interior surface bounding a chamber, the tank assembly including a sidewall encircling the chamber and extending between a first end and an opposing second end, the first end bounding an opening to the chamber, and a lid movable between a first position wherein the opening to the chamber is exposed and a second position wherein the lid is disposed over the opening. A collapsible bag is removably disposed within the chamber of the tank assembly, the collapsible bag bounding a compartment adapted to hold a fluid. A mechanism is provided for controlling the temperature of fluid within the collapsible bag when the collapsible bag is positioned within chamber of the tank assembly.

A method for mixing a fluid includes: dispensing a first volume of a fluid into a flexible container, the flexible container being at least partially disposed within the chamber of a support housing; repeatedly moving the support housing and the flexible container contained therein so as to mix the first volume of fluid within the flexible container; adding further fluid into the flexible container after moving the support housing to form a second volume of fluid; and manipulating a mixing element within the flexible container so as to mix the second volume of fluid.

A method for mixing a fluid includes: dispensing a first volume of a fluid into a flexible container, the flexible container being at least partially disposed within the chamber of a support housing; repeatedly moving the support housing and the flexible container contained therein so as to mix the first volume of fluid within the flexible container; adding further fluid into the flexible container after moving the support housing to form a second volume of fluid; and manipulating a mixing element within the flexible container so as to mix the second volume of fluid.

A fluid mixing system includes a support housing having an interior surface bounding a chamber. A flexible bag is disposed within the chamber of the support housing, the flexible bag having an interior surface bounding a compartment. An impeller is disposed within the chamber of the flexible bag. A drive shaft is coupled with the impeller such that rotation of the drive shaft facilitates rotation of the impeller. A drive motor assembly is coupled with the draft shaft and is adapted to rotate the drive shaft. An adjustable arm assembly is coupled with the drive motor assembly and is adapted to move the drive motor assembly which in turn moves the position of the drive shaft and impeller. An electrical controller can control movement of the adjustable arm.

A fluid mixing system includes a support housing having an interior surface bounding a chamber. A flexible bag is disposed within the chamber of the support housing, the flexible bag having an interior surface bounding a compartment. An impeller is disposed within the chamber of the flexible bag. A drive shaft is coupled with the impeller such that rotation of the drive shaft facilitates rotation of the impeller. A drive motor assembly is coupled with the draft shaft and is adapted to rotate the drive shaft. An adjustable arm assembly is coupled with the drive motor assembly and is adapted to move the drive motor assembly which in turn moves the position of the drive shaft and impeller. An electrical controller can control movement of the adjustable arm.

A microwavable container for use in a microwave oven that includes provisions to stir or mix food during microwave cooking. This mixing action is achieved by utilizing the motor of the microwave oven. Such mixing provides more even heating of food, and reduces the need to stop the microwave oven to manually stir food.

A pan, including: a first cogwheel, being annular for surrounding the container of the pan, and for being rotational in relation to the container; a motor, for rotating the first cogwheel; and a stirring element extending from the first cogwheel into the container, thereby the stirring element stirs the contents of the container.

An agitator mounting assembly is provided for hanging an agitator relative to a container for enabling rotation of the agitator to agitate fluid in a container. The agitator mounting assembly is configured to align the agitator both radially relative to and longitudinally along a central longitudinal container axis of the container. The agitator mounting assembly includes an annular base member and a coupling member that cooperatively engage one another to hang the agitator in the container. The annular base member is removably couplable to the container and provides for access to a shaft of the agitator disposed in the container. The coupling member is removably couplable to the shaft and is supported by the annular base member when coupled to the shaft to thereby support the hanging of the agitator from the agitator mounting assembly.

An agitator for being disposed in a container and rotated to agitate fluid in the container includes a shaft and an impeller attached thereto. The shaft, being supported relative to the container, provides an input for attachment of a rotation mechanism for causing rotation of the impeller and shaft. The impeller includes an impeller body defined by a hub portion for receiving and being mounted to the shaft, and a plurality of blades extending radially outwardly from a longitudinal axis of the hub portion. The impeller body is a single piece of unitary construction, such as where the plurality of blades are formed in a manner that the blades are integral with the hub portion at the formation of the blades.