This disclosure relates to equipment utilized to manufacture chemical agents, particularly biopharmaceuticals, using Disposable Containers (DCs).

Method and apparatus for continuous processing to perform chemical or physical reactions comprises a tube in which internal axial stirrer blades mounted at the periphery of the tube are driven by a drive system. This generates tangential flow of material at the perimeter. Stationary axial baffles mounted inside the swept path of the stirrer blades convert tangential flow into turbulence and radial mixing.

Method and apparatus for continuous processing to perform chemical or physical reactions comprises a tube in which internal axial stirrer blades mounted at the periphery of the tube are driven by a drive system. This generates tangential flow of material at the perimeter. Stationary axial baffles mounted inside the swept path of the stirrer blades convert tangential flow into turbulence and radial mixing.

Disclosed is direct ink write (DIW) print extrusion head for 3D printing of viscous elastomers. The disclosed print extrusion head comprises a mixer assembly, comprising a fluid distribution cap coupled to a carrier, an in-line mixer coupled to the fluid distribution cap. A cooling jacket surrounds the in-line mixer. A nozzle is coupled to the in-line mixer and protrudes below the cooling jacket over a work surface. The position of the nozzle relative to the work surface is changeable. At least one heat source is on the chassis and disposed adjacent to the fluid distribution cap. The at least one heat source comprises a heat guiding element to direct heat to a region onto the work surface below the nozzle.

A device made of a temperature control device (1) and a stirring head (2), wherein the temperature control device (1) comprises an adapter (3), and the adapter (3) comprises an outer adapter surface (7), an adapter interior (8) with an inner adapter surface (9), and a temperature control element (10) for heating the adapter (3) to an operating temperature, and wherein the adapter (3) is open on a face side toward the adapter interior (8), and the stirring head (2) has a bearing hub (4) with an outer bearing hub surface (5), an inner bearing hub surface (6) and a bearing bush, and the bearing bush is positively fitted into the bearing hub (4), while abutting the inner bearing hub surface (6), and wherein the adapter interior (8) is designed for accommodating the bearing hub (4), with the outer bearing hub surface (5) abutting the inner adapter surface (9) essentially completely.

The present disclosure is directed to a blending system including a blending mechanism, wherein said blending mechanism comprises a mixing chamber including at least a submersible motor, at least a high shear mixer, at least an impeller and at least a multistage retention time cup.

An apparatus for agitation of fluids is described that comprises an agitation chamber, an impeller configured to have a motor, a shaft, and blades, and a plurality of baffles. Further, the plurality of baffles have a predetermined shape and configuration. Further, the plurality of baffles are placed on a side wall of the agitation chamber.

A mixing apparatus for mixing particles in a liquid and its use are disclosed. The mixing apparatus comprises a tank having a bottom and a substantially vertical side wall, an agitation means comprising a rotation shaft located vertically and centrally in the tank, and an impeller arranged at a height above the bottom at the end of the rotation shaft and the impeller being a downward pumping axial or mixed flow impeller. The bottom is equipped with a corrugated formation comprising alternate consecutive ridges and valleys, the ridges and valleys extending radially in relation to a center of the bottom, whereby the valleys concentrate and channel the mixing power near to the bottom to direct the flow of the liquid and to increase the velocity of the flow near to the bottom.

A reactor system includes a support housing having an interior surface bounding a chamber, the chamber having a vertically extending central longitudinal axis. A flexible bag is disposed within the chamber of the support housing and has an interior surface bounding a compartment. A mixing element is disposed within the compartment of the flexible bag. A drive element, such as a drive shaft, is secured the mixing element, wherein the mixing element is laterally offset from and/or is angled relative to the vertically extending central longitudinal axis of the support housing.

A vertical low-pressure reactor with stirred tank for leaching polymetal minerals and concentrates of lead, copper, zinc, iron and/or the mixtures thereof, in a solid-gas-liquid three-phase suspension system. The low-pressure vertical reactor with stirred tank consists of: a cylindrical vertical container with three or four deflectors evenly distributed across the 360; a stirring system made up of two impellers coupled to a rotary shaft, that provides adequate reaction and interaction of the metal species of interest; a space of the volume of the reactor, corresponding to 20% to 35% of the total volume of the container, located at the top of the reactor and which acts as a gas chamber that provides a continuous feed of oxygen; and a system of coils placed on the outside or inside surface of the reactor to ensure efficient heat-transfer reactions and controlled kinetics.