The present set of embodiments relate to a bioproduction system, method, and apparatus for creating a scalable bioreactor system. Specifically, the present set of embodiments enable the determination of bioreaction performance characteristics of a commercial scale by matching operational parameters between a small test scale bioreaction to that of a commercial scale bioreaction. The system and methods do not rely on simply making bioreactor apparatuses across scales the same dimensionally which would not account for differences in fluid dynamic properties between very small to very large volumes, but requires tuning of a variety of systems (mixing assembly, sparger system, and headspace airflow system) in conjunction with one another to achieve predictive outcomes.

The present set of embodiments relate to a bioproduction system, method, and apparatus for creating a scalable bioreactor system. Specifically, the present set of embodiments enable the determination of bioreaction performance characteristics of a commercial scale by matching operational parameters between a small test scale bioreaction to that of a commercial scale bioreaction. The system and methods do not rely on simply making bioreactor apparatuses across scales the same dimensionally which would not account for differences in fluid dynamic properties between very small to very large volumes, but requires tuning of a variety of systems (mixing assembly, sparger system, and headspace airflow system) in conjunction with one another to achieve predictive outcomes.

A stirrer is provided that can more efficiently achieve shearing applied, by an action of an intermittent jet flow, to a fluid to be processed. The stirrer concentrically includes a rotor including a blade, a partition wall, and a screen, wherein: the screen includes a plurality of slits in a circumferential direction thereof and screen members located between the adjacent slit; by rotating at least the rotor of the two components, the fluid to be processed is discharged from the inside to the outside of the screen as the intermittent jet flow through the slit of the screen; the screen has a cylindrical shape having a circular cross section; an opening of the slit provided on the inner wall surface of the screen is used as an inflow opening; openings of the plurality of slits provided on the outer wall surface of the screen are used as outflow openings; and the width of the outflow openings in the circumferential direction is set to be smaller than the width of the inflow opening in the circumferential direction.

A stirrer is provided that can more efficiently achieve shearing applied, by an action of an intermittent jet flow, to a fluid to be processed. The stirrer concentrically includes a rotor including a blade, a partition wall, and a screen, wherein: the screen includes a plurality of slits in a circumferential direction thereof and screen members located between the adjacent slit; by rotating at least the rotor of the two components, the fluid to be processed is discharged from the inside to the outside of the screen as the intermittent jet flow through the slit of the screen; the screen has a cylindrical shape having a circular cross section; an opening of the slit provided on the inner wall surface of the screen is used as an inflow opening; openings of the plurality of slits provided on the outer wall surface of the screen are used as outflow openings; and the width of the outflow openings in the circumferential direction is set to be smaller than the width of the inflow opening in the circumferential direction.

A mixing arrangement for mixing two solutions, a mixer settler unit and a use. The mixing arrangement includes a mixing device arranged in the mixing space for rotating therein, the mixing device comprising at least two helical bars supported around a shaft and rising upwards from the bottom section of the mixing space. The helical bars are fixed to the shaft with support spokes. The ratio of the diameter (D) of the mixing device to the average diameter (T) of the mixing space, that is D/T, is 0.47 at most.

A mixing-extruding head apparatus for a three-dimensional (3D) printer for building residential houses and other objects, which enables printing of right-angled corners, the apparatus comprising a container for mixing mortar, the container comprising a funnel (1), a two-part helix (6) inside the container for mixing the mortar for building said objects, wherein the two-part helix (6) is installed on a main axis (2) inside the funnel (1) and the helix (6) comprises an inner metal part (6a) and an outer rubber part (6b), and wherein the helix (6) has at least one thread (turn), and an exit nozzle (14). The bottom part of the exit nozzle (14) is on each of its sides equipped with one of four blades (17), which are controlled by a servo-pneumatic system with computer-controlled commands for building the objects, wherein each of the blades is connected to a piston moved by a pneumatic cylinder; wherein all four pneumatic cylinders are connected with four electromagnetic valves, which generate pneumatic signals.

A mixing assembly includes a main flow conduit having an inlet end and an opposite outlet, a source of pressurized air at the inlet end, a container of stucco in fluid communication with the flow conduit, and a source of water in fluid communication with the flow conduit between the outlet and the container. The pressurized air draws stucco from the container into the flow conduit, and also draws water into the flow conduit to form an atomized slurry.

A stirrer is provided such that a fluid being processed can be more efficiently shown by way of the action of an intermittent jet flow and processing capacity can be improved. The stirrer concentrically includes a rotor that includes a plurality of flat vanes and that rotates, and a screen that is place around the rotor. The screen includes a plurality of slits in the circumferential direction thereof, and screen members that are positioned between adjacent slits. The fluid being processed is discharged by rotation of the rotor from the inside of the screen to the outside as an intermittent jet flow through the slits. The width of the distal working face on the distal end of the vane in the rotational direction is smaller than the width of the basal end of the vane in the rotational direction.

An integrated production system for a ternary material includes an agitating device, a water washing tank, an agitated nutsche filter and a dryer arranged in sequence along a travel path of a ternary material, where the agitating device is used to agitate a material; the water washing tank is used to carry out even pulping and provide a reaction space; the agitated nutsche filter is used to realize an agitating and filtering operation on the material; the dryer is used to dry the material. The integrated production system can meet the high requirements of the large-scale ternary material production for the water content, washing effect, particle crystal form, purity and closed operation. The integrated production system can also effectively ensure the production capacity and production efficiency of the system while satisfying the requirements of green manufacturing for efficiency enhancement, energy saving, consumption reduction and emission reduction.

An integrated production system for a ternary material includes an agitating device, a water washing tank, an agitated nutsche filter and a dryer arranged in sequence along a travel path of a ternary material, where the agitating device is used to agitate a material; the water washing tank is used to carry out even pulping and provide a reaction space; the agitated nutsche filter is used to realize an agitating and filtering operation on the material; the dryer is used to dry the material. The integrated production system can meet the high requirements of the large-scale ternary material production for the water content, washing effect, particle crystal form, purity and closed operation. The integrated production system can also effectively ensure the production capacity and production efficiency of the system while satisfying the requirements of green manufacturing for efficiency enhancement, energy saving, consumption reduction and emission reduction.