A negative pressure protection system has a cover enclosing an inner space, a ventilation duct fluidly communicating with an air outlet port of the cover, a filter having an inlet end communicating with the ventilation duct, and an air exhausting device connected to an outlet end of the filter. The air exhausting device draws air out from the inner space of the cover via the ventilation duct. The air is filtered and purified by the filter and then is exhausted away by the exhausting device.

A medial isolette is provided. A foldable box-type enclosure and base rail type enclosure are provided which supplies an economical and easily assembled isolation chamber. A flexible drape is provided to further isolate the patient and effectively control a negative pressure environment within the isolette. Access sports with integrated or removable gloves are provided to access the patient when the isolette is in use. A component access panel is provided for ducted connection of patient gas circuits and leads.

A medial isolette is provided. A foldable box-type enclosure and base rail type enclosure are provided which supplies an economical and easily assembled isolation chamber. A flexible drape is provided to further isolate the patient and effectively control a negative pressure environment within the isolette. Access sports with integrated or removable gloves are provided to access the patient when the isolette is in use. A component access panel is provided for ducted connection of patient gas circuits and leads.

A collapsible air isolation apparatus is disclosed. The apparatus may include a collapsible frame including a base and a set of rigid panel elements at least partially enclosing a volume of space, where the set of rigid panel elements is foldably hinged to at least one of the base or another of the rigid panel elements, and where at least one panel of the set of rigid panel elements comprises an open space for mounting a motor for moving air. The apparatus may include the motor for moving air configured to create a negative pressure within the volume of space of the collapsible frame.

Systems and methods for a hyperbaric chamber are disclosed herein. A hyperbaric chamber includes a chamber that is configured to seal a volume of air. The chamber includes one or more ports that are configured to connect to an air supply and one or more platforms inside the chamber. The chamber includes one or more sensors that monitor an environment inside the chamber.

The present disclosure is directed to methods of treating subject patients (such as humans, animals, plants) suffering from a pathogenic disease such as COVID-19 in humans, via the administration of pressure changes in the patient sufficient to cause a pressure differential to be created between the inside and outside of the outer membrane or envelope of the pathogen thereby destroying or disabling the pathogen. In one embodiment, a hyperbaric chamber is used to administer pressure increases and/or pressure decreases to create such pressure differential. The hyperbaric chamber could comprise a single user or multi-user unit, a pressurized body suit, or the pressurizable fuselage of an aircraft. In another embodiment, patients are placed in an aircraft, and the cabin pressure, while on the ground, or in flight, is adjusted upwardly or downwardly to create such pressure differential. The pressure differential methods can also include the use of external gases to enter the patient's body and/or lungs to facilitate disruption of the pathogen outer membrane as well as application of variations in temperature and/or humidity. A mobile treatment unit is also disclosed. Also disclosed are methods of using ultrasonic cavitation or MRI (or other sonic or magnetic field forces sufficient to disrupt the functionality of the pathogen), or a combination of ultrasound and MRI on the exterior of a patient in a desired anatomical region of the patient to assist with the destruction or disabling of a pathogen infecting that anatomical region of the patient, e.g., the patient's lungs, said method being employed at ambient pressures or in an increased or decreased pressure environment created within a hyperbaric chamber. The ultrasound and/or MRI methodologies could also be used to treat other pathogenically afflicted areas of the patient's body. Additionally, a pressure-differential method of sterilization of medical equipment is disclosed employing a hyperbaric or other pressure or vacuum chamber. Also disclosed is an enhanced method of nonsurgical fat reduction in humans by employing ultrasonic cavitation within a hyperbaric chamber, including the use of HBOT therapies. Furthermore, the use of these methodologies and systems have application in treatment of patients post-infection and in other areas of medicine and health, such as for example, treating wounds, the effects of aging, inflammation, and the effects of other maladies.

A disposable, isolating intubation device is described, the device comprising a flexible, spherical compartment inflatable from a collapsible state, the flexible, spherical compartment being substantially transparent and having a closed end and an open end distal from the closed end defining an inside volume for receiving a head, shoulders and a portion of a torso of a patient and methods of using.

Various systems and devices are provided for determining a weaning readiness for weaning a patient from a thermoregulated microenvironment. In one example, a method includes receiving a plurality of current patient parameters of a patient housed in a thermoregulated microenvironment, applying a weaning model to the plurality of current patient parameters to generate a weaning index representing a likelihood that the patient will be successfully weaned from the microenvironment if weaned at that time, the weaning model trained to correlate the current patient parameters with the likelihood based on historical data of prior patients and known outcomes for those prior patients, and outputting the weaning index for display on a display device and/or for storage in a medical record of the patient.

Various systems and devices are provided for determining a weaning readiness for weaning a patient from a thermoregulated microenvironment. In one example, a method includes receiving a plurality of current patient parameters of a patient housed in a thermoregulated microenvironment, applying a weaning model to the plurality of current patient parameters to generate a weaning index representing a likelihood that the patient will be successfully weaned from the microenvironment if weaned at that time, the weaning model trained to correlate the current patient parameters with the likelihood based on historical data of prior patients and known outcomes for those prior patients, and outputting the weaning index for display on a display device and/or for storage in a medical record of the patient.

The present invention relates to a means of reducing exposure to aerosolized particulate pathogens thereby (1) safely increasing throughput, (2) increasing surgical flow rates and (3) improving surgical suite turnover times (i.e., limiting non-productive facility space utilization) through air quality monitoring, generally. Further, the present invention couples air quality sensors with real-time processing technology by combining algorithmic enabled and mechanical means of lowering risk levels of both patients, medical professionals and ancillary staff alike.