A shaker includes a base, a holder and a drive assembly. The holder is movably disposed on the base. The drive assembly includes a first eccentric shaft, a second eccentric shaft, a drive shaft, plural magnetic members and a power source. The first eccentric shaft includes a first part and a second part which are non-coaxial. The first part is pivoted on the holder. The second eccentric shaft includes a third part and a fourth part which are non-coaxial. The third part is pivoted on the holder. Two ends of the drive shaft respectively correspond to the second and the fourth parts. The magnetic members are respectively disposed on the second, the fourth parts and the two ends of the drive shaft. The power source is used for rotating the first eccentric shaft, and rotating the second eccentric shaft through the magnetic members and the drive shaft.

The present invention relates to a system for performing assays on a solid phase to measure the level of analyte in a sample. Such a system may perform immunoassays using electrochemiluminescence (ECL) including a counterbalanced orbital shaking apparatus for assay consumables.

The present invention relates to a system for performing assays on a solid phase to measure the level of analyte in a sample. Such a system may perform immunoassays using electrochemiluminescence (ECL) including a counterbalanced orbital shaking apparatus for assay consumables.

An apparatus for substantially horizontally oscillating one or more vessels containing a liquid, a solid, or a mixture thereof that operates to thoroughly disrupt and mix solid and liquid substances in vessels, like test tubes. The apparatus provides superior mixing through oscillation of the vessels both horizontal and vertical directions through the use of one or more springs and rotating mechanical components. The apparatus includes a circular rotating ring having a toothed circumference that rotates horizontally, at least one vessel support having a compartment configured to hold the one or more vessel vessels and a spring attached to the housing and in constant contact with each of the one or more vessel supports.

An apparatus for substantially horizontally oscillating one or more vessels containing a liquid, a solid, or a mixture thereof that operates to thoroughly disrupt and mix solid and liquid substances in vessels, like test tubes. The apparatus provides superior mixing through oscillation of the vessels both horizontal and vertical directions through the use of one or more springs and rotating mechanical components. The apparatus includes a circular rotating ring having a toothed circumference that rotates horizontally, at least one vessel support having a compartment configured to hold the one or more vessel vessels and a spring attached to the housing and in constant contact with each of the one or more vessel supports.

An apparatus configured for mixing the contents of one or more fluid containers includes a fluid container support platform configured to hold one or more fluid containers. The fluid container support platform is configured to index the container to one or more specified locations and to be moved in an orbital path about an orbital center independently of the rotation about the central axis of rotation. The apparatus further includes an indexing drive system configured to effect indexing movement of the container support platform and a vortex drive system configured to effect powered orbital movement of the container support platform about the orbital center. An evaporation limiting insert placed within containers reduces exposure of the fluid contents of the container to atmospheric air, thereby reducing susceptibility of the fluid contents to evaporation.

The present disclosure provides materials and methods for producing droplet libraries with thousands of distinct reagents. The monodispersed libraries prepared according to the methods provided herein use multiwall plates and are compatible with microfluidic processing.

An insert for a liquid-holding container may include a body comprising a wall, an open top end and a bottom end, and a generally tubular lumen extending from the open top end to the open bottom end. The insert may include a plurality of first openings formed in the wall, the first openings being situated between the top and bottom ends, wherein each of the plurality of first openings defines an area, and wherein the plurality of first openings have substantially the same dimensions. The insert may include one or more second openings formed in the wall, the one or more second openings being situated between the top and bottom ends, wherein each of the one or more second openings defines an area that is greater than the area defined by any of the first openings, wherein the one or more second openings have substantially the same dimensions.

An insert for a liquid-holding container may include a body comprising a wall, an open top end and a bottom end, and a generally tubular lumen extending from the open top end to the open bottom end. The insert may include a plurality of first openings formed in the wall, the first openings being situated between the top and bottom ends, wherein each of the plurality of first openings defines an area, and wherein the plurality of first openings have substantially the same dimensions. The insert may include one or more second openings formed in the wall, the one or more second openings being situated between the top and bottom ends, wherein each of the one or more second openings defines an area that is greater than the area defined by any of the first openings, wherein the one or more second openings have substantially the same dimensions.

An insert for a liquid-holding container includes a body comprising a wall, open first and second ends, and a lumen extending from the open first end to the open second end. A plurality of first openings are formed in the wall, each of the first openings defining an area, and one or more second openings are formed in the wall, each of the one or more second openings defining an area that is greater than the area defined by any of the first openings. The first openings are arranged in a first row of at least three first openings in axial alignment and a second row of at least three first openings in axial alignment. At least one of the one or more second openings is situated closer to the first end than any of the first openings, and each of the first and second openings is sized to permit the passage of a liquid.