B01F31/22

Method and device for measuring process parameters in liquid cultures

A method for measuring process parameters in liquid cultures in a plurality of microreactors of at least one microtiter plate includes continuously agitating the liquid cultures using an orbital agitator at least until the reaction is completed in all the microreactors. In order to allow process parameters also of such substances which themselves do not have any fluorescence activity to be measured with relatively low complexity and within a short time, 2D fluorescence spectra are recorded in a plurality of in particular different liquid cultures in the microreactors of agitated microplates. A device for carrying out the method is also disclosed.

Method and device for measuring process parameters in liquid cultures

A method for measuring process parameters in liquid cultures in a plurality of microreactors of at least one microtiter plate includes continuously agitating the liquid cultures using an orbital agitator at least until the reaction is completed in all the microreactors. In order to allow process parameters also of such substances which themselves do not have any fluorescence activity to be measured with relatively low complexity and within a short time, 2D fluorescence spectra are recorded in a plurality of in particular different liquid cultures in the microreactors of agitated microplates. A device for carrying out the method is also disclosed.

GRINDING SAMPLES USING ROTATIONAL AND LINEAR MOTION
20230116439 · 2023-04-13 ·

The disclosure is directed to a sample preparation apparatus for grinding or homogenizing test samples. More specifically, the disclosure relates to grinding samples using rotational and linear motion. Grinding samples can be accomplished with an apparatus with a slider-crank mechanism that is attached to an oscillating connecting linkage. The amplitude of oscillatory motion can be greater than or equal to a length of a sample processing chamber.

GRINDING SAMPLES USING ROTATIONAL AND LINEAR MOTION
20230116439 · 2023-04-13 ·

The disclosure is directed to a sample preparation apparatus for grinding or homogenizing test samples. More specifically, the disclosure relates to grinding samples using rotational and linear motion. Grinding samples can be accomplished with an apparatus with a slider-crank mechanism that is attached to an oscillating connecting linkage. The amplitude of oscillatory motion can be greater than or equal to a length of a sample processing chamber.

SHAKING PLATFORM HAVING AN ADJUSTABLE HOLDING DEVICE FOR CONTAINER FASTENING, HOLDING DEVICE AND LABORATORY SHAKING DEVICE
20220331760 · 2022-10-20 ·

The present invention relates to a shaking platform for a laboratory shaking device having an adjustable holding device for fastening at least one container, the shaking platform having a length and a width, and the holding device comprising: a base plate having a fastening device for fastening the holding device on the shaking platform, at least two supports that protrude from the base plate and that form a container-receiving space arranged between the supports, and at least two holding rods carried by the supports and running substantially parallel to the shaking platform, which holding rods delimit the container-receiving space and whose distance from one another can be adjusted via an adjusting rail, the length and the width being greater than a length of the holding rods. The present invention also relates to an adjustable holding device and a laboratory shaking device.

SHAKING PLATFORM HAVING AN ADJUSTABLE HOLDING DEVICE FOR CONTAINER FASTENING, HOLDING DEVICE AND LABORATORY SHAKING DEVICE
20220331760 · 2022-10-20 ·

The present invention relates to a shaking platform for a laboratory shaking device having an adjustable holding device for fastening at least one container, the shaking platform having a length and a width, and the holding device comprising: a base plate having a fastening device for fastening the holding device on the shaking platform, at least two supports that protrude from the base plate and that form a container-receiving space arranged between the supports, and at least two holding rods carried by the supports and running substantially parallel to the shaking platform, which holding rods delimit the container-receiving space and whose distance from one another can be adjusted via an adjusting rail, the length and the width being greater than a length of the holding rods. The present invention also relates to an adjustable holding device and a laboratory shaking device.

VORTEX APPARATUS HAVING SLOPED PLATFORM
20170326513 · 2017-11-16 ·

An apparatus includes a motor configured to move a platform on a predetermined orbit. The platform is connected to the motor, and the platform is configured to receive one or more vessels. Material included in each of the one or more vessels is mixed when the platform is moved on the predetermined orbit. The platform is sloped down, with respect to a horizontal axis, in a direction from any point along the predetermined orbit toward the center of the orbit.

Bioreaction container

A bioreaction container including a culture chamber configured to contain a culture solution and a life form in an inner space, the culture chamber having an open upper end; a chamber cover portion coupled to the upper end of the culture chamber, the chamber cover portion having a protruding tube provided on one side thereof so as to communicate with the inner space; a filter cap coupled to the protruding tube in an attachable/detachable manner so as to open/close the protruding tube; a gas introduction portion configured to penetrate the chamber cover portion and to communicate with the inner space so as to supply a predetermined gas into the inner space; and an acidity/basicity adjustment portion installed on the chamber cover portion while containing an adjustment solution that adjusts pH of the culture solution such that the adjustment solution is discharged into the inner space by pneumatic pressure.

ORBITAL SHAKER
20170312709 · 2017-11-02 ·

An orbital shaker device (1) for biotechnological and/or biomedical applications comprises a frame (10), a platform (15) for receiving biotechnological and/or biomedical containers (50), eccentric couplings (13, 14) for allowing an orbital movement of the platform (15) relative to the frame (10), counterweight units (17, 18) for balancing the orbital movement, and at least one motor (19) for driving the eccentric couplings (13, 14). The device comprises two eccentric couplings (13, 14) arranged near respective opposite edges (27, 28) of the platform (15), while each counterweight unit (17, 18) is arranged approximately in the plane of the combined center of gravity of the platform (15) and the containers (50). Furthermore, both eccentric couplings (13, 14) are driven by the motor (19) or motors, either directly or indirectly. In this way, an optimal vibration compensation is achieved while allowing an imaging unit (40) to be mounted underneath the platform (15).

Method for powdered drug reconstitution

Method of robot control is disclosed that includes the steps of: providing a user interface for introducing data indicative of a drug to be subjected to a reconstitution process; accessing an internal data base for outputting, for a selected drug, a list of primitive movements P1, P2, . . . Pi, . . . Pn to be used in the reconstructing process; operating the robot for executing sequentially the primitives and moving a container according to the instructions of the primitives; measuring, during the movement of the container under robot action, physical positions in the space and dynamic parameters of the container creating a list of registered data; comparing the measured positions in the space and the dynamic parameter with the corresponding ones of the primitive movements for selecting a list of eligible primitives if a sufficient approximation level is reached; elaborating selected eligible primitives together to generate instructions for the robot allowing a complex movement encompassing the simple movements; and using the robot for shaking the container according to the complex movement.