B01F31/22

Sample processing apparatus with integrated heater, shaker and magnet

Samples in an array of containers are processed by mounting the containers on a sample stage, moving magnets into proximity with bottoms of the containers of a first column of containers to apply a magnetic field, moving the magnets into proximity with bottoms of the containers of a second column, and moving heater elements into proximity with the container bottoms of the first column. While the magnetic field is applied to the containers of the second column, heat energy may be applied to the containers of the first column. The process may be repeated for additional columns. The containers may also be shaken to agitate the samples. A single apparatus may perform heating, shaking, and magnetic field application, without needing to transport the containers to different stations.

Disposable bioreactor systems and related methods
11986787 · 2024-05-21 · ·

A method for enhancing mixing and aeration of a liquid reaction medium in a toroidal bioreactor vessel includes dispensing a liquid reaction medium into an interior of a toroidal bioreactor vessel, the interior being bounded by an inner surface, a textured surface being arranged on at least a portion of the inner surface, the textured surface having a plurality of upstanding protuberances. The toroidal bioreactor vessel is rotated in an orbital motion such that there is a resonant frequency traveling wave of the fluid orbiting in one direction in the interior of the toroidal bioreactor vessel when a particular orbital speed is imparted to the toroidal bioreactor vessel.

Disposable bioreactor systems and related methods
11986787 · 2024-05-21 · ·

A method for enhancing mixing and aeration of a liquid reaction medium in a toroidal bioreactor vessel includes dispensing a liquid reaction medium into an interior of a toroidal bioreactor vessel, the interior being bounded by an inner surface, a textured surface being arranged on at least a portion of the inner surface, the textured surface having a plurality of upstanding protuberances. The toroidal bioreactor vessel is rotated in an orbital motion such that there is a resonant frequency traveling wave of the fluid orbiting in one direction in the interior of the toroidal bioreactor vessel when a particular orbital speed is imparted to the toroidal bioreactor vessel.

METHOD AND DEVICE FOR MEASURING PROCESS PARAMETERS IN LIQUID CULTURES

A method for measuring process parameters in liquid cultures in a plurality of microreactors of at least one microtiter plate includes continuously agitating the liquid cultures using an orbital agitator at least until the reaction is completed in all the microreactors. In order to allow process parameters also of such substances which themselves do not have any fluorescence activity to be measured with relatively low complexity and within a short time, 2D fluorescence spectra are recorded in a plurality of in particular different liquid cultures in the microreactors of agitated microplates. A device for carrying out the method is also disclosed.

Evaporation-controlling container inserts
10343127 · 2019-07-09 · ·

An apparatus configured for mixing the contents of one or more fluid containers includes a fluid container support platform configured to hold one or more fluid containers. The fluid container support platform is configured to index the container to one or more specified locations and to be moved in an orbital path about an orbital center independently of the rotation about the central axis of rotation. The apparatus further includes an indexing drive system configured to effect indexing movement of the container support platform and a vortex drive system configured to effect powered orbital movement of the container support platform about the orbital center. An evaporation limiting insert placed within containers reduces exposure of the fluid contents of the container to atmospheric air, thereby reducing susceptibility of the fluid contents to evaporation.

PRETREATMENT DEVICE AND PRETREATMENT METHOD FOR FOOD SAFETY DETECTION

A pretreatment device for food safety detection, including: a base; a vortex oscillator disposed on the base; and a container holding mechanism disposed on the base and configured to hold a container such that the container is positioned above the vortex oscillator, wherein the vortex oscillator is configured to cooperate with the container holding mechanism to treat materials contained in the container. The present disclosure further provides a pretreatment method for food safety detection. By means of the pretreatment device and the pretreatment method according to the present disclosure, it can perform pretreatment work of food safety detection efficiently and simply, and save labor costs.

Vibration device for petri dishes
10323224 · 2019-06-18 ·

A vibration generator causes a carrier to oscillate, rather than the housing of the vibration generator. The vibration generator is placed within the housing, which itself is not induced to oscillate, thus reducing or eliminating undesired noises due to excessive oscillations of the housing. The vibration generator transfers vibrations to the carrier for Petri dishes using at least one connecting element that is arranged between the carrier and the vibration generator. The connecting element protrudes through the wall of the housing and is sealed by a sealing element with respect to the wall.

SHAKING SYSTEM OF CELL CULTURE AND METHOD FOR SHAKING THE SAME

A shaking system of cell culture includes a shaking unit, a side visual unit, a top visual unit and a control unit. The side visual unit is located at one side of the shaking unit. The top visual unit is located above the shaking unit. The control unit is coupled signally with the shaking unit, the side visual and the top visual unit. In addition, a shaking method of cell culture is provided as well.

Apparatus, method and system for recording at least one variable during a biological/chemical process

An apparatus, a method and a system for the parallelized recording of at least one variable during a biological/chemical process are disclosed. A matrix, which has at least one container and which can be positioned on a measurement carrier, is provided to accommodate the liquid samples. A measuring unit, which comprises a controllable radiation source for electromagnetic radiation and at least one sensor for detecting electromagnetic radiation, is fixedly disposed in or on the measurement carrier. When at least one matrix with the containers is placed onto the measurement carrier, the respective measuring unit is assigned to the base of each container from the outside. During the measurement by the measuring unit, a movement device is used to move the measurement carrier with a defined radial movement about a fixed axis orthogonal to the gravitational force.

Orbital shaker with balancing device

An orbital shaker with a balancing device that automatically and passively compensates, without supply of external energy, forces and moments which are caused by imbalance and arise during operation, in particular as a result of a possible variable loading (mass, geometry of the containers, properties of the contents) and variable operating parameters (speed of rotation and shaking radius). The balancing device can be designed such that only the unbalance forces (static balancing) and/or the unbalance moments (dynamic balancing) are compensated.