An analysis system may perform operations on an analyte that may be combined with multiple regents prior to being introduced into a flow cell. The instrument may include a volume into which the reagents to be combined with the analyte are aspirated one-by-one. The volume may be formed as a serpentine channel in a valve manifold associated with sippers for aspirating the reagents. The reagents may then be mixed by cycling a pump to move the reagents within the mixing volume or channel. For this, the reagents may be aspirated from a recipient into the volume or channel, ejected back into the recipient, and this process may be performed repeatedly to enhance mixing.

A positive displacement mixer and method for mixing a product that mixes at least two materials into a homogenous product. The positive displacement mixer has at least one positive displacement element having a length, a primary compartment, and a moving element, and two or more minor positive displacement elements each having a length, a minor compartment, and a moving element. The primary compartment and the minor compartments are fluidly connected and during mixing the primary compartment and minor compartments are closed to the atmosphere.

Mixing device (1) and fluid mixing method, by means of successive transfers between syringes. The mixing method comprises placing a pair of syringes (2, 3) in the mixing device (1), adjusting a variable fixing element adaptable to the pair of syringes (2, 3) and selecting and running a mixing programme, being the mixing force, the speed and the range and the number of transfers adjustable. The mixing device comprises a mobile carriage (7) longitudinally movable and fixing elements (8, 9) with an adjustable distance between them. The invention allows for the mixing or emulsifying of blood fluids with different viscosity, particularly a protein gel and a platelet-rich plasma, for the preparation of dermatological formulations, in a versatile, hygienic and effective manner.

What is disclosed in the present invention is to provide a quantitative transfer pipette structure, wherein an anti-backflow compartment is configured in the first bulb. The dimensions and locations of the first bulb, the second bulb and the third bulb are specifically configured to aspirate and transfer a specific volume of the liquid to a container, mix the liquid with the substance in the container by pressing and releasing the specific bulbs, so as to achieve the effects of precise quantification and sufficient mixing.

It is necessary to efficiently agitate a small amount of sample (such as blood) and reagent (such as diluted solution) in a short time with a dispensing probe having a constant tube inner diameter. An automatic analysis device, by a dispensing probe, executes an aspiration step of aspirating a reagent from a reagent vessel; a first dispensing and aspiration step of dispensing a first liquid amount of the aspirated reagent to a reaction vessel and aspirating, from the reaction vessel, a second liquid amount of a mixed liquid obtained by mixing the reagent and the sample in the reaction vessel; and a final dispensing step of dispensing the aspirated mixed liquid and the reagent in a predetermined dispensing amount. A first liquid amount Va is less than a predetermined dispensing amount Vdil.

Devices and methods for preparing a slurry for coating onto a substrate. The devices and methods of the present disclosure relate to providing a slurry in a closed volume with at least one passage. The slurry includes a solvent, a powder, and a binder. The slurry can also include a dispersion agent. The slurry is forced repeatedly under high pressure through the at least one passage in a first flow direction and then back through the at least one passage in a second flow direction, opposite the first flow direction. The forcing homogenously disperses the powder and the binder within the solvent. Both sides of the substrate are then coated simultaneously with the slurry extruded from the closed volume after the forcing. Curing of the coated slurry includes freeze drying to preserve the porosity of the slurry on the substrate.

A tattoo ink mixing apparatus has a housing having a cavity, a plunger movable between a first position and a second position, and a dynamic member disposed in the cavity and adapted to engage with the plunger distal end. The dynamic member moves in response to movement of the plunger and alternatively creates a suction force and an expulsion force in the opening of the distal end of the housing as the plunger moves between its first and second positions.

Example fluidic channels for microfluidic devices are disclosed. In examples disclosed herein, an example microfluidic device includes a body having a microfluidic network. The microfluidic network includes a main fluid channel to transport a biological fluid from a first cavity of the microfluidic network to a second cavity of the microfluidic network. An auxiliary fluid channel is in fluid communication with to the main fluid channel. The auxiliary fluid channel has a first end and a second end. The first end is in fluid communication with the main fluid channel and the second end is spaced from the main fluid channel. A fluid actuator is positioned in the auxiliary fluid channel to induce fluid flow in the main fluid channel.

An apparatus having a spectrometer and techniques for use thereof for efficient and effective point-of-care diagnostics are provided. In one aspect, a device is provided. The device includes: an intake port; fluidic channels connecting the intake port to a detecting chamber(s), wherein the detecting chamber(s) is configured to permit optical measurements of a fluid sample; a vent leading away from the detecting chamber(s); and a liquid blocker between the detecting chamber(s) and an opening of the vent, wherein the liquid blocker permits air to pass therethrough while at the same time restricting liquid flow. A method for analyzing a fluid sample is also provided. The method includes: introducing the fluid sample to the device; contacting the fluid sample with a reagent(s) prior to the fluid sample entering the detecting chamber(s); and making optical measurements of the fluid sample in the detecting chamber(s).

Provided in one implementation is a method that includes introducing a volume of raw material into a chamber of a cavitation machine. The raw material can include a mixture comprising a powder and a solvent. The powder can have a first average particle size in the raw material. The method includes applying a hydrodynamic cavitation process to the raw material to produce a product material. The powder can have a second average particle size, smaller than the first average particle size, in the product material. The method includes causing the product material to exit the cavitation chamber and drying the product material to remove the solvent. Apparatus employed to apply the method are also provided.