A method for manufacturing beverage or other liquid containing bubbles uses a system for manufacturing bubble-containing liquid that includes: a bubble generating unit that generates fine bubbles in a liquid; a bubble collapsing unit that is connected to the bubble generating unit to collapse the fine bubbles contained in the bubble-containing liquid supplied from the bubble generating unit by making the bubble-containing liquid pass through the bubble collapsing unit and irradiating the bubble-containing liquid with ultrasonic wave; and a storage unit that is connected to the bubble collapsing unit to store the bubble-containing liquid supplied from the bubble collapsing unit. The method includes: a bubble generating step of generating the fine bubbles in the liquid by the bubble generating unit; a bubble collapsing step of generating superfine bubbles by forming an ultrasonic field by the bubble collapsing unit to collapse the fine bubbles contained in the liquid; and a storage step of storing the bubble-containing liquid containing the superfine bubbles by the storage unit. Consequently, beverage or other liquid containing the superfine bubbles can be manufactured.

A method is provided for producing fine-bubble water by resonance foaming and vacuum cavitation, and a device for manufacturing each of ultra-fine-bubble water of hydrogen gas having a reducing radical function, ultra-fine-bubble water of air and oxygen gas having an oxidizing radical function, ozone ultra-fine-bubble water having a sterilization function enabled by ozone, and fine-bubble water of nitrogen/carbon dioxide gas for increasing the ability to preserve the freshness of raw agricultural products, livestock products, and marine products.

A bubble generation device includes: a metallic narrow tube (10) through which water passes; and a pump that pressure-feeds the water containing a gas component into the metallic narrow tube (10). A drawer (11) in which a path through which the water passes is narrower than the front and the rear thereof in the flow direction of the water is disposed on the inside of the metallic narrow tube (10). The drawer (11) has the rectangular cross section orthogonal to the flow direction. The gas component contained in the water is dissolved in the water by pressure-feeding the water to the drawer (11), bubbles are evolved due to a decrease in pressure in the drawer (11), turbulent flow is generated in the water in the drawer (11) to crush bubbles in the water by the shearing force thereof, and bubbles are crushed by a shock wave caused by transonic flow occurring in the water that has exited from the drawer (11).

Devices, systems and methods including a sonicator for sample preparation are provided. A sonicator may be used to mix, resuspend, aerosolize, disperse, disintegrate, or de-gas a solution. A sonicator may be used to disrupt a cell, such as a pathogen cell in a sample. Sample preparation may include exposing pathogen-identifying material by sonication to detect, identify, or measure pathogens. A sonicator may transfer ultrasonic energy to the sample solution by contacting its tip to an exterior wall of a vessel containing the sample. Multipurpose devices including a sonicator also include further components for additional actions and assays. Devices, and systems comprising such devices, may communicate with a laboratory or other devices in a system for sample assay and analysis. Methods utilizing such devices and systems are provided. The improved sample preparation devices, systems and methods are useful for analyzing samples, e.g. for diagnosing patients suffering from infection by pathogens.

The invention relates to a device for the fragmentation of DNA samples that are in solution in a container, said device comprising: a vessel for receiving a liquid, the vessel being provided with means for producing ultrasonic waves so as to spread ultrasonic waves through the liquid; and a first support element resting on the vessel, the device being characterized in that it further comprises a second support element having a passage designed to receive the container, the second support element being suspended by at least one suspension element forming at least one swivel joint, such that a lower portion of the container can be immersed in the liquid.

The present invention provides a liquid treatment apparatus with ring vortex processor for treating a liquid medium and, more particularly, to an apparatus and method for enhancing chemical reactions occurring in processes utilizing hydrodynamic cavitation. The liquid treatment apparatus with ring vortex processor efficiently utilizes fluid energy for cavitation bubble formation, maximizes the temperatures and pressures generated during bubble collapse, and minimizes damage caused by erosion.

Devices, systems and methods including a sonicator for sample preparation are provided. A sonicator may be used to mix, resuspend, aerosolize, disperse, disintegrate, or de-gas a solution. A sonicator may be used to disrupt a cell, such as a pathogen cell in a sample. Sample preparation may include exposing pathogen-identifying material by sonication to detect, identify, or measure pathogens. A sonicator may transfer ultrasonic energy to the sample solution by contacting its tip to an exterior wall of a vessel containing the sample. Multipurpose devices including a sonicator also include further components for additional actions and assays. Devices, and systems comprising such devices, may communicate with a laboratory or other devices in a system for sample assay and analysis. Methods utilizing such devices and systems are provided. The improved sample preparation devices, systems and methods are useful for analyzing samples, e.g. for diagnosing patients suffering from infection by pathogens.

Devices, systems and methods including a sonicator for sample preparation are provided. A sonicator may be used to mix, resuspend, aerosolize, disperse, disintegrate, or de-gas a solution. A sonicator may be used to disrupt a cell, such as a pathogen cell in a sample. Sample preparation may include exposing pathogen-identifying material by sonication to detect, identify, or measure pathogens. A sonicator may transfer ultrasonic energy to the sample solution by contacting its tip to an exterior wall of a vessel containing the sample. Multipurpose devices including a sonicator also include further components for additional actions and assays. Devices, and systems comprising such devices, may communicate with a laboratory or other devices in a system for sample assay and analysis. Methods utilizing such devices and systems are provided. The improved sample preparation devices, systems and methods are useful for analyzing samples, e.g. for diagnosing patients suffering from infection by pathogens.

An automatic chemical analyzer, maintenance kit, and maintenance method capable of, even in a case where a problem of the automatic chemical analyzer occurs, clarifying a cause of the problem in a user site and coping with the problem without collecting a device or a component. The automatic chemical analyzer maintenance kit is connectable to an automatic chemical analyzer including a reaction vessel for accommodating at least a pipetted specimen and a reagent, and a stirring mechanism including a piezoelectric element that irradiates the reaction vessel with ultrasonic waves. The piezoelectric element includes a plurality of divided electrodes. The automatic chemical analyzer maintenance kit measures, for each of the divided electrodes, an absolute value of an impedance of the piezoelectric element and a phase difference between a voltage applied to the divided electrode and a current, and determines if there is an abnormality an electrode based on a measurement result.

Method and apparatus for controlling acoustic treatment of a sample to mediate a tagmentation process used on double stranded DNA.