Provided is a generating method for generating an ultra-fine bubble-containing liquid in which multiple types of UFB s of different gas components are mixed at a desired concentration ratio, and a manufacturing apparatus for a liquid containing ultra-fine bubbles. Multiple types of UFB-containing liquids are generated for each gas contained by the UFBs, and the UFB-containing liquids are mixed with each other based on a mix proportion of a desired UFB concentration.

An object of the present disclosure is to provide a manufacturing apparatus of an ultra fine bubble-contained liquid that can be utilized effectively because high concentration ultra fine bubbles are maintained for a long time at the time of manufacturing of the ultra fine bubble-contained liquid. One embodiment of the present invention is a manufacturing apparatus of an ultra fine bubble-contained liquid, which includes: a container having a gas supply port through which gas is introduced and a liquid supply port through which a liquid is introduced; and a generation unit inside the container, which is configured to cause an ultra fine bubble to occur in the liquid in which the gas is dissolved.

A generating method for generating a UFB at a desired component ratio, and a manufacturing apparatus and a manufacturing method for a liquid containing a UFB at a desired component ratio are provided. To this end, a mixed solution in which multiple types of gases are dissolved at a predetermined ratio is generated, and a UFB is generated by heating the mixed solution with a heating element.

Provided is an UFB generating apparatus and an UFB generating method capable of efficiently generating an UFB-containing liquid with high purity. To this end, the ultrafine bubble generating apparatus includes a pre-processing unit that performs predetermined pre-processing on a liquid W and a generating unit that generates ultrafine bubbles in the liquid on which the pre-processing is performed. The generating unit generates the ultrafine bubbles by causing a heating element, which is provided in the liquid on which the pre-processing is performed, to generate heat to generate film boiling on an interface between the liquid and the heating element.

The present invention relates to a method and an apparatus for a fast thermo-optical characterisation of particles. In particular, the present invention relates to a method and a device to measure the stability of (bio)molecules, the interaction of molecules, in particular biomolecules, with, e.g. further (bio)molecules, particularly modified (bio)molecules, particles, beads, and/or the determination of the length/size (e.g. hydrodynamic radius) of individual (bio)molecules, particles, beads and/or the determination of length/size (e.g. hydrodynamic radius).

Provided is a UFB generating apparatus that can achieve compactness, power saving, and low cost. To this end, a liquid containing unit for supplying a liquid to a UFB generating head is fluidly linked to the UFB generating head at a position higher than the UFB generating head in a direction of gravitational force.

Provided is a UFB generating apparatus capable of manufacturing an ozone UFB-contained liquid with high purity and quality. To this end, in the UFB generating apparatus capable of generating UFBs containing ozone by causing film boiling in ozone water, a liquid contact portion to come into contact with the ozone water is made of a material with corrosion resistance to ozone water.

Provided is an ultrafine bubble generating method and an ultrafine bubble generating apparatus capable of efficiently generating a UFB-containing liquid with high purity. To this end, a flow passage inner volume is varied by using a flow passage inner volume varying element, the liquid is pressurized such that the liquid passes through a narrow portion at high speed and flows into a depressurizing area.

Provided is a UFB-containing liquid production apparatus that can efficiently produce a UFB-containing liquid with a UFB generation unit. The UFB-containing liquid production apparatus includes: a gas dissolution unit that produces a gas-dissolved liquid by dissolving a gas into a liquid supplied from a liquid supply unit; a UFB generation unit that generates UFBs in the flowing-in gas-dissolved liquid; and a circulation path that supplies the gas-dissolved liquid to the UFB generation unit and supplies a UFB-containing liquid produced by the UFB generation unit to the liquid supply unit. In the circulation path, there is provided a micro-bubble reduction unit that reduces an amount of micro-bubbles contained in the gas-dissolved liquid to flow into the UFB generation unit.

An object of the present disclosure is to improve the generation efficiency of a UFB-contained liquid in a generation apparatus having a circulation mechanism. One embodiment of the present invention is an ultra fine bubble generation apparatus including: a first tank that stores a liquid; a generation unit configured to generate an ultra fine bubble in the liquid output from the first tank; a second tank that stores the liquid output from the generation unit; and a liquid passage that inputs again the liquid stored in the second tank to the first tank, and the ultra fine bubble generation apparatus includes a blocking configuration that blocks an ultra fine bubble included in the stored liquid from being input again to the first tank.