The present invention relates to a method and an apparatus for a fast thermo-optical characterisation of particles. In particular, the present invention relates to a method and a device to measure the stability of (bio)molecules, the interaction of molecules, in particular biomolecules, with, e.g. further (bio)molecules, particularly modified (bio)molecules, particles, beads, and/or the determination of the length/size (e.g. hydrodynamic radius) of individual (bio)molecules, particles, beads and/or the determination of length/size (e.g. hydrodynamic radius).

An electronic-sensing & magnetic-modulation (ESMM) biosensor device and methods of using the same, where the device incorporates electrical, microfluidic, and magnetic subsystems. The device and methods of using such a device can be applied to high throughput point-of-care screening for the quantification and evaluation of a subject's immune response to pathogenic infections, which can be useful for: early diagnosis, stratifying high-risk subjects infected with a pathogen; and determining the status or effectiveness of a therapeutic response.

Provided are methods and materials for assaying known and candidate therapeutics for inotropic cardiac effects in one or more in vitro assay formats comprising preloaded cardiac tissues and/or organoids.

A microfluidic system includes a chip holder that holds a microchip including a plurality of reservoirs, a chip cover, a sealing member; a dispensing probe, a suction mechanism, a first storage where a first cleaning solution is stored, a second storage where a second cleaning solution is stored, a pump, a channel switch, and a controller. The channel switch is configured to switch between a channel through which the first cleaning solution is suctioned from the first storage and a channel through which the second cleaning solution is suctioned from the second storage. The controller controls operations of the channel switch and the pump.

Devices and methods for performing pre-analysis sample processing of biological and chemical samples using robotic liquid handlers are disclosed. Methods for solid phase extraction, protein precipitation and filtration of biological and chemical samples using automation and the devices in a rapid and convenient way are described.

The present disclosure relates to an organ-on-a-chip, and according to the present disclosure, the organ-on-a-chip includes a first layer having a first microfluidic channel to culture a first organ cell, a second layer having a second microfluidic channel, a third layer having a third microfluidic channel to culture a second organ cell, a first membrane to spatially separate the first microfluidic channel from the second microfluidic channel, and a second membrane to spatially separate the second microfluidic channel from the third microfluidic channel, thereby measuring the rate of absorption of a test drug into the first organ cell and the second organ cell at the same time.

A method for performing a lateral flow assay is provided. The method includes inserting a sample cartridge (201) in a dark chamber (220) and activating a light emitter (251) in the dark chamber (220). The method includes focusing an optical coupling mechanism (115a, 115b) in an image-capturing device (100a, 100b) to optimize an image of a sensitive area (202) in the sample cartridge (201) and capturing, with an image capturing device (100a, 100b), an image of a sensitive area (202) in the sample cartridge (201) after a selected period of time. The method also includes providing the image of the sensitive area (202) to a processor, wherein the processor comprises an image-capturing application (122). A system and a computer-implemented method to perform at least partially the above method are also provided.

The present invention relates to a standard material composition for verifying a bio-analysis equipment, comprising quantum dot-containing nanoparticles. Through a standard strip and/or a standard tray, which are made of the standard material composition, the present invention may increase the analysis accuracy of a bio-analysis equipment.

A method and system for determining the presence or absence of cancerous cells within subject tissue. The method includes: providing a material that includes a peptide component configurable in a non-binding form when disposed in a neutral pH environment, and in a binding form when disposed in an acidic pH environment, wherein the peptide component is configured to produce a first Raman spectrum when subjected to one or more predetermined wavelengths of light; administering the material to a subject tissue; interrogating the subject tissue with light; sensing the subject tissue for light emitted from the subject tissue, and producing signals representative of the sensed emitted light; analyzing the signals to determine a presence or absence of the first Raman spectrum; and determining the presence or absence of cancerous cells based on the presence or absence of the first Raman spectrum within the sensed light emitted from the subject tissue.

A multi-sample container disposal module is provided with a discharging mechanism comprising a storage box, the storage box being internally provided with a storage space, wherein the storage space is divided into a first storage cavity and a second storage cavity via a partition plate in the storage space; a transition mechanism, two ends of which are respectively a receiving end and a discharging end, wherein the receiving end is provided with a receiving rack and the discharging end is provided with a rotating structure and a discharging plate, and a driving structure is arranged between the receiving rack and the rotating structure; and a printing mechanism located above the transition mechanism, wherein the printing mechanism comprises a laser head, and a position of an emission light source of the laser source corresponds to a position of the rotating structure up and down.